Study of Drugs and Other Biologically-Active Substances Perspective in Prevention and Treatment of Important Lifestyle Diseases

Charles University research centre  (UNCE 204026/2012)

Principal investigator: Prof. RNDr. Petr Solich, CSc.

Project duration: 1. 1. 2012 – 31. 12. 2017

Financial support: 22,257,750 Kč   (about 900,000 EUR)

Strategic objectives of the project

The aim of the project is to study newly used drugs in clinical medicine as well as biologically-active substances of natural origin from the perspective of the prevention and treatment of important lifestyle diseases, especially cardiovascular and oncologic diseases and degenerative diseases associated with human ageing. The project involves studying the influence of significant biological markers in the early diagnosis of these diseases along with the identification of new potential biomarkers and the isolation and identification of new enzymes as a potential targets for the inhibition associated with the therapy of these diseases. An integral part of the project is the isolation and identification of new substances of natural origin, especially those with anti-oxidation activity in relation to the prevention of cardiovascular and oncologic diseases. This multi-discipline project directly follows and significantly extends the collaboration of perspective researchers (juniors) and connects their work with that of experienced, extensively published researchers (seniors) from several departments at the Faculty of Pharmacy, Charles University in Hradec Králové who have dealt with the prevention and treatment of lifestyle diseases.

© 2017 Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic

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