Laboratory of respiratory pharmacology

The laboratory studies substances acting on the respiratory using both in vitro and in vivo methods.

Current research topics

  • In vitro evaluation od quinazoline alkaloids derivatives by the method of isolated trachea
  • In vivo study of promising compounds under physiological conditions and in experimentally induced allergic asthma (determination of lung resistance and compliance)
  • Determination of acute toxicity potential of antiasthmatics

Current staff  

Faculty employees

Recent publications

Collaboration

at the faculty

international

  • prof. Julio Cortijo and prof. Esteban Morcillo (Facultad de Medicina, Universidad de Valencia, Spain)

Grants

Succesfully finished grants

  •  2002 Charles University in Prague: EFFECTS OF ORAL ANTIOXIDANTS  IN RAT MODEL OF ALLERGIC ASTHMA. Principal investigator: Jana Suchánková - Pourová, Pharm.D., Ph.D.
  • 2006 Ministry of Education, Youth and Sports: EXTENSION OF PRACTICAL TEACHING IN TOXICOLOGY, MONITORING CHANGES IN AIRWAY REACTIVITY.  Principal investigator: Marie Vopršalová, Pharm.D., Ph.D.
  • 2007 Ministry of Education, Youth and Sports: INNOVATION OF PRACTICAL EDUCATION  IN  TOXICOLOGY. Principal investigator: Marie Vopršalová, Pharm.D., Ph.D.
  • 2012 - 2014 Charles University in Prague, in collaboration with Department of anorganic and organic chemistry: Novel Types of Chiral Organocatalysts Derived from the Alcaloid Vasicinone

ongoing grants

  • 2015 - 2017 Czech grant agency, in collaboration with Department of anorganic and organic chemistry: Natural Lactones and Lactams: Towards Diverse Biological Activities through Purposeful Synthetic Manipulations


 

 

 

© 2017 Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
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