Mgr. Andrej Kováčik

Born: March 28, 1989

Address: Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové,
Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic

Phone: +420 495 067 283
E-mail: kovacika@faf.cuni.cz

Research Gate

Current Job

  • member of Skin Barrier Research Group

  • PhD student at the Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University

  • researcher assistant of Czech Science Foundation projects

  • principal researcher in Charles University project (GAUK)

Education

  • since 2013: PhD study in Bioorganic Chemistry, Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University; research project: “Synthesis and study of ceramides in model lipid membranes” (supervisor: Assoc. Prof Dr Kateřina Vávrová, PhD)

  • 2008 – 2013: Master of Pharmacy (Mgr., equiv. MPharm.) at Faculty of Pharmacy in Hradec Králové, Charles University in Prague; diploma thesis: “Synthesis and study of ceramides based on 6-hydroxysphingosine” at the Department of Inorganic and Organic Chemistry (supervisor: Assoc. Prof Dr Kateřina Vávrová, PhD)

Research Interests

  • skin, skin barrier, stratum corneum, skin lipids, ceramides

  • sphingolipid chemistry – synthesis, NMR evaluation

  • model lipid membranes – multi-lamellar membrane systems, permeability studies (HPLC), TEWL measuring

  • model membrane biophysics – infrared spectroscopy, X-ray powder diffraction

Teaching Activities

  • teaching of “Chemical Laboratory Technique” (practical exercises) and “Organic Chemistry” (practical exercises) at the Faculty of Pharmacy in Hradec Králové, Charles University

  • co-supervisor of MPharm. students at the Faculty of Pharmacy in Hradec Králové, Charles University (diploma thesis - 5x + 1x Erasmus)

Grants

  • since 2016: Czech Science Foundation and German Science Foundation joint project 16-25687J "Interdependencies between Inflammatory Processes and Barrier Lipids in Diseased Skin" (with Prof. Sarah Hedrich, Freie Universität Berlin) – co-worker

  • since 2014: Grant of Charles University in Prague (GAUK 1868214) – principal researcher

  • since 2013: Czech Science Foundation: „Lipid membrane models – a new tool for studying pathophysiology of skin diseases at a molecular level“ (13-23891S) – researcher

  • 2011 - 2013: Czech Science Foundation: Synthesis and structure-activity relationships of skin ceramides and compounds targeting them (207/11/0365) – co-worker

Awards

  • 2017: 3rd place in competition at trainee course "Interpretation of vibrational spectra”(Prague, Czech Republic)

  • 2012: 1st Prize at The International Student Research Conference (Zentiva Company, Prague)

Publications

  1. Kováčik A, Pullmannová P, Maixner J, Vávrová K. manuscript in preparation

  2. Čuříková BA, Procházková K, Filková B, Diblíková P, Svoboda J, Kováčik A, Vávrová K, Zbytovská J. submitted 

  3. Svoboda M, Hlobilová M, Marešová M, Sochorová M, Kováčik A, Vávrová K, Dolečková I. submitted

  4. Stahlberg S, Eichner A, Sonnenberger S, Kováčik A, Lange S, Schmitt T, Demé B, Hauss T, Dobner B, Neubert RHH, Huster D. submitted

  5. Sochorová M, Staňková K, Pullmannová P, Kováčik A, Zbytovská J, Vávrová K. Sci. Rep. 2017, (IF2016 = 4.3) in press

  6. Vávrová K, Kováčik A, Opálka L. Eur. Pharm. J. 2017, 64 (1):1-8

  7. Pullmannová P, Pavlíková L, Kováčik A, Sochorová M, Školová B, Slepička P, Maixner J, Zbytovská J, Vávrová K. Biophys. Chem. 2017, 224, 20-31 (IF2015 = 2.4)

  8. Kováčik A, Šilarová M, Pullmannová P, Maixner J, Vávrová K. Langmuir2017, 33, 2890-2899 (IF2015 = 4.0)

  9. Školová B, Kováčik A, Tesař O, Opálka L, Vávrová K. Biochim. Biophys. Acta - Biomembranes2017, 1859(5), 824-834 (IF2015 = 3.7)

  10. Opálka L, Kováčik A, Maixner J, Vávrová K. Langmuir. 2016, 32(48), 12894-12904 (IF2015 = 4.0)

  11. Kováčik A, Opálka L, Šilarová M, Roh J, Vávrová K. RSC Adv. 2016, 6(77), 73343-73350 (IF2015 = 3.3)

  12. Opálka L, Kováčik A, Sochorová M, Roh J, Kuneš J, Lenčo J, Vávrová K. Org. Lett. 2015, 17(21):5456-59 (IF2015 = 6.7)

  13. Wallmeyer L, Lehnen D, Eger N, Sochorová M, Opálka L, Kováčik A, Vávrová K, Hedtrich S. J. Dermatol. Sci. 2015, 80(2):102–10 (IF2015 = 3.7)

  14. Kováčik A, Roh J, Vávrová K. ChemBioChem. 2014, 15(11):1555-62 (IF2015 = 2.8)

  15. Školová B, Hudská K, Pullmannová P, Kováčik A, Palát K, Roh J, Fleddermann J, Estrela-Lopis I, Vávrová K. J. Phys. Chem. B. 2014, 18(35):10460-70 (IF2015 = 3.2)

Professional Memberships

  • since 2015: Czech Chemical Society

  • since 2014: Czech Pharmaceutical Society (sections: Chemical Drugs, Clinical Pharmacy, History of Pharmacy)

Work Experience and Fellowships

  • 2017 (6 months): Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät der Universität Leipzig (prof. Huster, Leipzig, Germany)

  • 2017 (1 week): Training Course “Interpretation of vibrational spectra” (Prague, Czech Republic)

  • 2015: Frank Laboratory of Neutron Physics (JINR, Dubna, Russian Federation)

  • 2012 (3 months): Thomayer Hospital (Pharmacy, Prague, Czech Republic)

  • 2012/2013 (3 months): Homolka Hospital (Pharmacy, Prague, Czech Republic)

Presentations at Conferences

2017:

  • XVII. Interdisciplinary Meeting of Young Biologists, Biochemists and Chemists, Milovy, Czech Republic (poster) 

2016:

  • 6th Postgraduate and 4th Postdoc Conference, Hradec Králové, Czech Republic (oral presentation)
  • Perspectives in Percutaneous Penetration, La Grande Motte, France (poster)
  • The 5th Czech Lipidomics Conference, Prague, Czech Republic (poster)
  • The 45th Conference Drug Synthesis and Analysis, Hradec Králové, Czech Republic (oral presentation)
  • 4th European Joint Theoretical/Experimental Meeting on Membranes, Bratislava, Slovakia (poster)

2015:

  • 5th Postgraduate and 3rd Postdoc Conference, Hradec Králové, Czech Republic (oral presentation)
  • Gordon Research Conference: Barrier Function of Mammalian Skin, Waterville, New Hampshire, USA (poster)
  • 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Olomouc, Czech Republic (poster)

2014:

  • 4th Postgraduate and 2nd Postdoc Conference, Hradec Králové, Czech Republic (oral presentation)
  • Perspectives in Percutaneous Penetration, La Grande Motte, France (poster)
  • Skin Forum (Percutaneous Penetration – Measurement, Modulation and Modelling), Prague, Czech Republic (poster)
  • 49th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Lázně Bělohrad, Czech Republic (poster)

2013:

  • 48th Advances in Organic, Bioorganic and Pharmaceutical Chemistry, Špindlerův Mlýn, Czech Republic (poster)

2012:

  • International Student Research Conference, Prague, Czech Republic (oral presentation; 1st Price)

Additional Skills

  • languages: English, German, Russian (basics)

  • computer skills: OS Windows, MS Office, MestreNova, ChemDraw, GraphPad, OPUS, X'Pert Data Viewer

  • driving licence “B”

Other Activities

  • 2016: co-author of the exposition of Department of Inorganic and Organic Chemistry at OpenDay of Faculty of Pharmacy

  • 2016: colaboration in “SCIO” tests (chemistry) for grammar students

  • 2015: main author of the exposition of Faculty of Pharmacy in Hradec Králové at “Nábřeží vysokých škol” exhibition (Hradec Králové)

  • 2014: main author and coordinator of the exposition of Faculty of Pharmacy in Hradec Králové at “Nábřeží vysokých škol” exhibition (Hradec Králové)
    Kováčik A. Čas. čes. lék. 2014, 86(10): 29 (article in Czech)

  • 2013: co-author of the exposition of Faculty of Pharmacy in Hradec Králové at “The Day of Science” exhibition (Prague)
    Kováčik A, Pilařová V. Čas. čes. lék. 2013, 85(12): 26 (article in Czech)

  • since 2011: guide and worker in the Czech Pharmaceutical Museum in Kuks

Interests and Hobbies

  • sports: swimming, running, fitness

  • music: alternative rock and alternative pop

 

© 2017 Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
Website information | Powered by Kentico