Assoc. Prof. PharmDr. Zdeňka Šklubalová, Ph.D.

Acting Head of Department of Pharmaceutical Technology,
Charles University in Prague, Faculty of Pharmacy in Hradec Králové

Tel. +420 495067390
Email: zdenka.sklubalova@faf.cuni.cz

Education

2011 Assoc. Prof. in Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové

1999 Ph.D. degree in Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové

1985 PharmDr. degree at Charles University in Prague, Faculty of Pharmacy in Hradec Králové

1984 Master degree at Charles University in Prague, Faculty of Pharmacy in Hradec Králové

Professional Memberships

Chair of Board for Postgraduate Study on Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové

Member of Board for Postgraduate Study on Pharmaceutical Technology-Galenic Pharmacy, Veterinary and Pharmaceutical University in Brno, Faculty of Pharmacy

European Pharmacopoeial Committee, Strasbourg, Member of Group 12 (Dosage forms)

Czech Pharmacopoeial Committee of the Ministry of Health, Head of the Section of Pharmaceutical Technology

Czech Pharmacopoeial Committee of the Ministry of Health, Member of group for Stability of extemporaneous dosage forms, the Section of Pharmacy

Czech Pharmaceutical Association, Member of the Section of Pharmaceutical Technology

Teaching activities

Guarantor of the subjects: Pharmaceutical Technology, Technology of homeopathic preparations, Development of drugs, Industrial Pharmacy, Manufacturing of pharmaceutical preparations, Extemporaneous preparation in hospital pharmacy

Lecturer in Pharmaceutical Technology (Dosage Forms, Sterile dosage forms)

Lecturer in Extemporaneous preparation in hospital pharmacy

Tutor of Master Thesis (more than 50 defended) and Doctoral Thesis (15 defended) on Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové

Tutor of postgraduate students on Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy in Hradec Králové (currently four students)

Co-author of the textbook: ŘEHULA, M. a kol.: Návody k základním praktickým cvičením z farmaceutické technologie. Praha, Karolinum 2013, s.103, ISBN 978-80-246-2378-8.

Research focus

  • Flow behaviour of particulate matter in pharmaceutical technology
  • Formulation aspects of liquid dosage forms
  • Formulation aspects of sterile dosage forms

Publications

KLOVRZOVÁ, S., ZAHÁLKA, L., KŘÍŽ, T., ZAHÁLKOVÁ, O., MATYSOVÁ, L., ŠKLUBALOVÁ, Z., HORÁK, P.: Extemporaneous sotalol hydrochloride oral solutions for use in paediatric cardiology: Formulation and stability study. Eur. J. Hosp. Pharm. 2016, 23, 33-37. ISSN 2047-9956. IF 0,471. doi: 10.1136/ejhpharm-2015-000711.

MATYSOVÁ, L., ZAHALKOVÁ, O., KLOVRZOVÁ, S., ŠKLUBALOVÁ, Z., SOLICH, P., ZAHÁLKA, L.: Development of a gradient HPLC method for the simultaneous determination of sotalol and sorbate in oral luqiud preparations using solid core stationary phase. J. Anal. Methods Chem. 2015, Article ID 806736, 6 p. http://dx.doi.org/10.1155/2015/806736. ISSN 2090-8865. IF = 0,948

ČUPERA, J., LÁNSKÝ, P., ŠKLUBALOVÁ, Z.: Sampling times influence the estimate of parameters in the Weibull dissolution model. Eur. J. Pharm. Sci. 2015, 78, 171-176. ISSN 0928-0987. IF 3,350. doi: http://dx.doi.org/10.1016/j.ejps.2015.07.015

ŠKLUBALOVÁ, Z., HURYCHOVÁ, H.: The effect of the size of a conical hopper aperture on the parameters of the flow equation of sorbitol and its size fractions. Čes. Slov. Farm., 2015, 64 (1-2), 14-18. ISSN 1210-7816.

ŠKLUBALOVÁ, Z., ZATLOUKAL, Z.: Flow rate and flow equation of pharmaceutical free-flowable powder excipients. Pharm. Dev. Technol., 2013, 18 (1), 106-111. DOI:10.3109/10837450.2011.640686.

ZAHÁLKA, L., MATYSOVÁ, L., ŠKLUBALOVÁ, Z., KLOVRZOVÁ, S., SOLICH, P.: Simultaneous determination of propranolol hydrochloride and sodium benzoate in oral liquid preparations by HPLC. Chromatographia. 2013, 76:1553–1558. DOI 10.1007/s10337-013-2457-z.

KLOVRZOVÁ, S., ZAHÁLKA, L., MATYSOVÁ, L., HORÁK, P., ŠKLUBALOVÁ, Z.: Pediatric oral solutions with propranolol hydrochloride for extemporaneous compounding: the formulation and stability study. Čes. Slov. Farm., 2013, 62 (1), s. 35-39.

KLOVRZOVÁ, S., MALIŠ, J., ČAPKOVÁ, Š., HOSTAŠA, J., HORÁK, P., ŠKLUBALOVÁ, Z.: Magistraliter receptury s propranololem v pediatrii, Farm. obzor 2013, 4-5, 84-88.

ZATLOUKAL, Z., ŠKLUBALOVÁ, Z.: The effect of orifice geometry on particle discharge rate for a flat-bottomed, cylindrical hopper. Particul. Sci. Technol., 2012, 30, s.316-328. DOI:10.1080/02726351.2011.573839.

KLOVRZOVÁ, S., ŠKLUBALOVÁ, Z.: Pediatrické lékové formy v magistraliter přípravě II. Perorální roztoky a suspenze. Prakt. Lékáren. 2012, 8 (2), s. 80-84.

ŠKLUBALOVÁ, Z.: Odhad osmolarity infuzních roztoků pomocí metod USP. Prakt. Lékáren. 2012, 8 (4), s. 175-176.

ZATLOUKAL, Z., ŠKLUBALOVÁ, Z.: The influence of orifice height on flow rate of powder excipients. Pharmazie, 2011, 64 (12), s. 953-955. DOI: http://dx.doi.org/10.1691/ph.2011.1074

ŠKLUBALOVÁ, Z., ZATLOUKAL, Z.: Area under rheogram as multi-point viscosity characteristic of the sterilized hydrogels of hypromellose. Acta Pol. Pharm. Drug Res., 68 (4), 2011, s. 565-569.

ŠKLUBALOVÁ, Z., ZATLOUKAL, Z.: The relationship between osmolarity and osmolality of infusion solutions of monosaccharides. J. Pharm. Sci. Res., 2010, 2 (9), s. 545-548.

ŠKLUBALOVÁ, Z., ZATLOUKAL, Z.: Optimization of regression equation for prediction of viscosity of aqueous solutions of the cellulose derivatives. Pharm. Dev. Technol., 13 (5), 2008, s. 359-365

Grants and projects

2015-2018 Project No. 322315/2015 of Grant Agency of Charles University. HURYCHOVÁ, H., ŠKLUBALOVÁ, Z., et al: The study of fractal aspects of flowability of particulate matter in pharmaceutical technology.

2011-2015 Technology Institute TAČR TA01010128: Research of lyophilized tablets for allergen vaccines. (Coordinator A. Jabo, SevaPharma)

2015 Charles University ŠKLUBALOVÁ, Z., KLOVRZOVÁ, S. Development of new subject " Extemporaneous preparation in hospital pharmacy" for students in study programm Pharmacy at Faculty of Pharmacy of Charles University (Coordinator)

2013 Ministry of Education, Youth and Sports 1414/2013/A/a: ŠKLUBALOVÁ, Z. et al: Modernization of laboratory for practical training in subject Pharmaceutical Technology. (Coordinator)

2012-2014 Ministry of Education, Youth and Sports: MSMT OPVK CZ.1.07./2.2.00/28.0194 Inovation of study programm Pharmacy at Faculty of Pharmacy of Charles University (Coordinator prof. Wsol)

2005-2011 Ministry of Education, Youth and Sports: Institutional research plan MSM0021620822 “Research of novel drug structures” (Coordinator Prof. Karlíček)

© 2017 Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic

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