Publications

ED -Exclusive dedication
EGD -Exclusive grand dedication
GD- Grant dedication
 

2016

All with exclusive dedication

  1. Bartonkova I., Novotna A., Dvorak Z.Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity. PLoS ONE (2015), 10(3): e0121316

  2. Brtko J., Dvorak Z. Triorganotin compounds - ligands for "rexinoid" inducible transcription factors: Biologicaleffects. Toxicol Lett (2015), 234:50-58

  3. Srovnalova A., Vanduchova A., Svecarova M., Anzenbacherova E., Tomankova V.,Anzenbacher P., Dvorak Z. Effects of sulforaphane and its S- and R- enantiomers on the expression and activities of human drug-metabolizing cytochromes P450. J Funct Foods (2015), 14:487-501

  4. Sedlacek J., Svecarova M.METODY STANOVENÍ AKTIVITY PROTEASOMU A JEJICH APLIKACE. Chem Listy (2015), 109:198-203

  5. Bialesova L., Novotna A., Macejova D., Brtko J., Dvorak Z. Agonistic effect of selected isoflavones on arylhydrocarbon receptor in a novel AZ-AhR transgenic gene reporter human cell line. Gen Physiol Biophys (2015), 34(3):331-334

  6. Najmanová I., Doseděl M., Hrdina R., Anzenbacher P, Filipský T., Říha M., Mladěnka P. Cardiovascular Effects of Coumarins Besides their Antioxidant Activity. Curr Top Med Chem, (2015), 15(9): 830-849

  7. Filipsky T, Riha M, Macakova K, Anzenbacherova E, Karlickova J, Mladenka P. Antioxidant Effects of Coumarins Include Direct Radical Scavenging, Metal Chelation and Inhibition of ROS-Producing Enzymes. Curr Top Med Chem, (2015), 15(5):415-431

  8. Tomankova V., Liskova B., Skalova L., Bartikova H., Bousova I., Jourova L., Anzenbacher P., Ulrichova J., Anzenbacherova E. Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity. Life Sci, (2015), 133:15-20

  9. Imran S., Ferretti P., Vrzal R. Different regulation of aryl hydrocarbon receptor-regulated genes in response to dioxin in undifferentiated and neuronally differentiated human neuroblastoma SH-SY5Y cells. Toxicol Mech Method, (2015), 25(9):689-697

  10. Illes P., Brtko J., Dvorak Z. Development and Characterization of a Human Reporter Cell Line for the Assessment of Thyroid Receptor Transcriptional Activity: A Case of Organotin Endocrine Disruptors. J Agric Food Chem, (2015), 63:7074-7083

  11. Grycova A., Doricakova A., Dvorak Z. Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor. Toxicol Lett, (2015), 239:67-72

  12. Bousova I., Bartikova H., Matouskova P., Lnenickova K., Zappe L., Valentova K., Szotakova B., Martin J., Skalova L. Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice. Nutrition Research, (2015), 35:901-909

  13. Boušová I., Matoušková P., Bártíková H., Szotáková B., Hanušová V., Tománková V., Anzenbacherová E., Lišková B., Anzenbacher P., Skálová L. Influence of diet supplementation with green tea extract on drugmetabolizing enzymes in a mouse model of monosodium glutamateinduced obesity. Eur J Nutr, (2016), 55:361-371

  14. Dvorak Z. Opportunities and challenges in using human hepatocytes in cytochrome P450 induction assays. Expert Opin Drug Metab Toxicol, (2015), 12(2):169-174

  15. Vrzal R. Anthocyanidins but not anthocyanins inhibit P-glycoprotein-mediated calcein extrusion – possible implication for orally administered drugs. Fundamental & Clinical Pharmacology, (2016), 30(3):248-252.

  16. Matalová P., Urbánek K., Anzenbacher P.Specific features of pharmacokinetics in children. Drug Metab Rev, (2016), 48(1):70-79

  17. Dvořák Z. Pivotal role of the aryl hydrocarbon receptor in modulations caused by benzo[a]pyrene and ketoconazole in the estrogenic responses induced by 17-estradiol in male goldfish. Environ Sci Pollut Res, (2016), 23(9):9247-9248

  18. Kubešová K., Dořičáková A., Trávníček Z., Dvořák Z. Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines. Toxicol Lett, (2016), 255:24-35

  19. Spicakova A., Anzenbacher P., Liskova B., Kuca K., Fusek J., Anzenbacherova E. Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators. Food Chem Toxicol, (2016), 88:100-104

  20. Scott E.E., C. Wolf C.R., Otyepka M., Humphreys S.C., Reed J.R., Henderson C.J., McLaughlin L.A., Paloncýová M., Navrátilová V., Berka K., Anzenbacher P., Dahal U.P., Barnaba C., Brozik J.A., Jones J.P., Estrada D.F., Laurence J.S., Park J.W., Backes W.L.The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function. Drug Metab Dispos, (2016), 44:576–590

  21. Kubešová K., Trávníček Z., Dvořák Z. Pleiotropic effects of gold(I) mixed-ligand complexes of 9-deazahypoxanthine on transcriptional activity of receptors for steroid hormones, nuclear receptors and xenoreceptors in human hepatocytes and cell lines. Eur J Mech Chem, (2016), 121:530-540

  22. Vrzal R., Illes P., Dvorak Z. Transplant drugs affect the expression of phase II and antioxidant enzymes in human carcinoma cells HepG2 but not in primary cultures of human hepatocytes: In vitro comparative study. Pharmacol Rep, (2016), 68:1008-1014

  23. Cibíček N., Roubalová L., Vrba J., Zatloukalová M., Ehrmann J., Zapletalová J., Večeřa R., Křen V., Ulrichová J. Protective effect of isoquercitrin against acute dextran sulfate sodium-induced rat colitis depends on the severity of tissue damage. Pharmacol Rep, (2016), 68:1197-1204

  24. Bartonkova I., Grycova A., Dvorak Z. Profiling of vitamin D metabolic intermediates towards VDR using novel stable gene reporter cell lines IZ-VDRE and IZ-CYP24. Chem Res Toxicol, (2016), 29:1211-1222

  25. Vanduchová A., Tománková V., Anzenbacher P., Anzenbacherova E. Influence of Sulforaphane Metabolites on Activities of Human Drug-Metabolizing Cytochrome P450 and Determination of Sulforaphane in Human Liver Cells. J Med Food, (2016), 19(12):1141-1146

  26. Kopečná-Zapletalová M, Krasulová K, Anzenbacher P, Hodek P, Anzenbacherová E. Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities. Xenobiotica, (2016), in press

  27. Kosina P., Dokoupilová A., Janda K., Sládková K., Silberová P., Pivodová V., Ulrichová J. Effect of Silybum marianum fruit constituents on the health status of rabbits in repeated 42day fattening experiment. Anim Feed Sci Technol, (2017), 223:128-140

  28. Soucek P, Hlavac V, Elsnerova K, Vaclavikova R, Kozevnikovova R, Raus K. Whole Exome Sequencing Analysis of ABCC8 and ABCD2 Genes Associating With Clinical Course of Breast Carcinoma. Physiol. Res. 2015; 64 (Suppl. 4): S549-S557

  29. Václavíková R, Hughes DJ, Souček P. Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease. Gene. 2015;571(1):1-8.

  30. Hlaváč V, Souček P. Role of family D ATP-binding cassette transporters (ABCD) in cancer. Biochem Soc Trans. 2015;43(5):937-942

  31. Petr Hodek , Johana Hrdinova, Iva Macova, Pavel Soucek, Iveta Mrizova, Kamila Burdova , Rene Kizek , Jiri Hudecek , Marie Stiborova. Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450. Neuroendocrinology Letters 2015, 36, 101-108

  32. Marie Stiborova, František Barta · Katerřina Levova, Petr Hodek, Eva Frei, Volker M, Heinz H. Schmeiser.The infuence of ochratoxin A on DNA adduct for mation by the carcinogen ar istolochic acid in rats. Arch Toxicol 2015; 89:2141–2158

  33. Zdislava Bostikova, Michaela Moserova, Petr Pavek, Marie Stiborova, Petr Hodek. Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen Activation. Neuroendocrinology Letters 2015; 36, 101-107

  34. Frantisek Barta, Katerina Levova , Petr Hodek ,Heinz H. Schmeiser , Volker M. Arlt , Marie Stiborova. The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy. Neuroendocrinology Letters 2015; 36 suppl 101-109

  35. Martin Ambrož, Iva Boušová , Adam Skarka , Veronika Hanušová 2, Věra Králová, Petra Matoušková , Barbora Szotáková and Lenka Skálová. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin.and Its Accumulation in Cancer Cells. Molecules 2015, 20, 15343-15358

  36. Hana Bártíková, Lenka Skálová, Kateřina Valentová, Petra Matoušková, Barbora Szotáková, Jan Martin, Vojtěch Kvita, Iva Boušová. Eff ect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo. Acta Pharm. 65 (2015) 65-73 DOI: 10.1515/acph-2015-0007

  37. Petra Matousková, Hana Bártíková, Iva Bousová, Lucie Levorová, Barbora Szotáková, and Lenka Skálová. Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice. Drug Metab Dispos, 2015; 43:258–265

  38. Alejandro Carazo and Petr Pávek. The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists. Sensors 2015;, 15, 9265-9276

  39. Tomas Smutny , Jurjen Duintjer Tebbens , Petr Pavek. Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 ‘‘missing heritability’’ enigma. Journal of Applied Biomedicine 2015, 13, 181-188

  40. Alejandro Carazo Fernández , Tomas Smutny , Lucie Hyrsová, Karel Berka, Petr Pavek. Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR). Toxicology Letters 2015; 233, 68–77

  41. Karlíčková J, Říha M, Filipský T, Macáková K, Hrdina R, Mladěnka P. Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway. Planta Med. 2015; 82(1-2):76-83.

  42. Krizkova V, Dubova M, Susova S, Vycital O, Bruha J, Skala M, Liska V, Daum O, Soucek P. Protein expression of ATP binding cassette transporters ABCC10 and ABCC11 associates with survival of colorectal cancer patients. Cancer Chemother Pharmacol. 2016; 78(3):595-603.

  43. Boušová, I., Skálová, L., Souček, P., Matoušková, P. The modulation of carbonyl reductase 1 by polyphenols. Drug Metabolism Reviews 47 (2015) 520-533

  44. Ambrož, M., Hanušová, V., Skarka, A., Boušová, I., Králová, V., Langhasová, L., Skálová, L. Essential oil from Myrica rubra leaves potentiated antiproliferative and pro-oxidative effect of doxorubicin and its accumulation in intestinal cancer cells. Planta Medica 82 (2016) 89-96

  45. Lněničková, K.; Procházková, E.; Skálová, L.; Matoušková, P.; Bártíková, H.; Souček, P.; Szotáková, B. Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells. Molecules 21 (2016) 1186-1197

  46. Karlíčková J, Říha M, Filipský T, Macáková K, Hrdina R, Mladěnka P. Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway. Planta Med. 2016 Jan;82(1-2):76-83.

  47. Iveta Najmanová´, Jana Pourová´, Marie Vopršalová´, Veronika Pilarova´, Vladimír Semecký´, Lucie Novákova´ and Přemysl Mladěnka. Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human mikroflóra decreases arterial blood pressure in rats. Mol. Nutr. Food Res. 2016, 60, 981–991

  48. Přemysl Mladěnka, Michal Říha, Jan Martin, Barbora Gorová, Aleš Matějíček, Jiřina Spilková. Fruit extracts of 10 varieties of elderberry (Sambucus nigra L.) interact differently with iron and copper. Phytochemistry Letters 18 (2016) 232–238

  49. Pavek P. Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions. Front Pharmacol. 2016 Nov 25;7:456

  50. Hyrsova L, Smutny T, Trejtnar F, Pavek P. Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation. by nuclear receptors and hepatospecific gene regulation. Drug Metab Rev. 2016 May;48(2):139-58.

  51. Lucie Hyrsova, Tomas Smutny, Alejandro Carazo, Stefan Moravcik, Jana Mandikova, Frantisek Trejtnar,Sabine Gerbal-Chaloin, Petr Pavek. Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation. Br J Pharmacol 173(10):1703-15

  52. Stiborová M, Arlt VM, Schmeiser HH. Balkan endemic nephropathy: an update on its aetiology. Arch Toxicol. 2016, 90: 2595-2615.

  53. Tomankova V., Vlckova A., Anzenbacher P., Bachleda P., Anzenbacherova E. Užívání přípravků ze zlatobýlu obecného (Solidago virgaurea) neovlivňuje metabolizmus současně podávaných léčiv. Klin Farmakol Farm, (2016), 30(1): 5-10

  54. Hanušová, V., Skálová, L., Ambrož, M., Králová, V., Langhasová, L., Matoušková, P. The effect of Myrica rubra essential oil and its components α-humulene and trans-nerolidol on adhesion and apoptosis. Cancer Cell & Microenvironment 2 (2015) e1058

  55. Chapters in books:

    Pavek, P a Smutny, T. Human Placental Trophoblasts Impact of Maternal Nutrition, Edited by by Asim K. Duttaroy, University of Oslo, Norway, Sanjay Basak National Institute of Nutrition (ICMR) Hyderabad, India.  The Aryl Hydrocarbon Receptor in the Human Placental Trophoblast The Impact of Nutraceuticals and Natural Products. CRC Press, Boca Raton, FL, USA, 2016

 

2015

 

  1. Bartonkova I., Novotna A., Dvorak Z. Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity.PLoS ONE, 2015, 10(3): e0
    exclusive dedication

  2. Brtko J., Dvorak Z. Triorganotin compounds - ligands for "rexinoid" inducible transcription factors: Biological effects.Toxicology Letters, 2015, 234:50-58

    Codedication for dr. Brtka (APVV-0160-11, APVV-0290-10,

    VEGA 2/0171/14, CEMAN grants). Prof. Dvorak   exclusive dedication.

  3. Srovnalova A., Vanduchova A., Svecarova M., Anzenbacherova E., Tomankova V.,

    Anzenbacher P., Dvorak Z. Effects of sulforaphane and its S- and R- enantiomers on the expression and activities of human drug-metabolizing cytochromes P450.  Journal of Functional Foods, 2015, 14:487-501

      exclusive dedication

  4. Sedlacek J., Svecarova M.METODY STANOVENÍ AKTIVITY PROTEASOMU A JEJICH APLIKACE.Chemické Listy, 2015, 109:198-203

      exclusive dedication

  5. Bialesova L., Novotna A., Macejova D., Brtko J., Dvorak Z. Agonistic effect of selected isoflavones on arylhydrocarbon receptor in a novel AZ-AhR transgenic gene reporter human cell line.General Physiology and Biophysics, 2015, 34(3):331-334

      exclusive dedication, Co-dedication dr. Brtka (APVV-0160-11, VEGA, 2/0171/14, CEMAN grants). ForProf. Dvorak   exclusive dedication.

  6. Najmanová I., Doseděl M., Hrdina R., Anzenbacher P, Filipský T., Říha M., Mladěnka P.Cardiovascular Effects of Coumarins Besides their Antioxidant ActivityCurrent Topics in Medicinal Chemistry, 2015, 15(9): 830-849.

      exclusive dedication (+SVV 260 064)

  7. Bousova I., Bartikova H., Matouskova P., Lnenickova K., Zappe L., Valentova K.,

    Szotakova B., Martin J., Skalova L. Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice.  Nutrition Research, 2015, 35:901-909

      exclusive dedication (+SVV 260 065)

  8. Filipsky T, Riha M, Macakova K, Anzenbacherova E, Karlickova J, Mladenka P. Antioxidant Effects of Coumarins Include Direct Radical Scavenging, Metal Chelation and Inhibition of ROS-Producing Enzymes. Current Topics in Medicinal Chemistry, 2015, 15(5):415-431

      exclusive dedication (+SVV 260 064)

  9. Imran S., Ferretti P., Vrzal R. Different regulation of aryl hydrocarbon receptor-regulated genes in response to dioxin in undifferentiated and neuronally differentiated human neuroblastoma SH-SY5Y cells.Toxicological Mechanisms and Methods, 2015, 25(9):689-697

    Codedication to ESF CZ.1.07/2.3.00/30.0041

  10. Illes P., Brtko J., Dvorak Z. Development and Characterization of a Human Reporter Cell Line for the Assessment of Thyroid Receptor Transcriptional Activity: A Case of Organotin Endocrine Disruptors.Journal of Agricultural and Food Chemistry, 2015, 63:7074-7083.

    Codedication to ESF CZ.1.07/2.3.00/30.0004 a

  11. Grycova A., Doricakova A., Dvorak Z. Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor. Toxicology Letters, 2015, 239:67-72

    Codedication SVV (studentský projekt UP IGA UP PrF-2015-003)

  12. Tomankova V., Liskova B., Skalova L., Bartikova H., Bousova I., Jourova L., Anzenbacher, P., Ulrichova J., Anzenbacherova E. Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity. Life Sciences, 2015, 133:15-20.

    Codedication to students projects UP (IGA UP LF-2015-004+IGA UP LF-2015-007) and

    ESF (CZ.1.07/2.3.00/30.0004).

  13. Boušová I., Matoušková P., Bártíková H., Szotáková B., Hanušová V., Tománková V.,

    Anzenbacherová E., Lišková B., Anzenbacher P., Skálová L. Influence of diet supplementation with green tea extract on drugmetabolizing enzymes in a mouse model of monosodium glutamateinduced obesity.   European Journal of Nutrition (in press)

    Codedication to  ESF CZ.1.07/2.3.00/30.0022 a CZ.1.07/2.3.00/30.0004

  14. Dvorak Z. Opportunities and challenges in using human hepatocytes in cytochrome P450 induction assays. Expert Opinions in Drug Metabolism and Toxicology (in press)

    Codedication to IGA MZd NT/13591.

  15. Soucek P, Hlavac V, Elsnerova K, Vaclavikova R, Kozevnikovova R, Raus K. Whole Exome Sequencing Analysis of ABCC8 and ABCD2 Genes Associating With Clinical Course of Breast Carcinoma.Physiol. Res. 2015; 64 (Suppl. 4): S549-S557

    Codedikation to IGA14055-3, MŠMT, LO1503 and SZU NIPH, 75010330)

  16. Václavíková R, Hughes DJ, Souček P. Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease. Gene. 2015;571(1):1-8.

    codedicationto EU RDF CZ.1.05/2.1.00/03.

    0076)

  17. Hlaváč V, Souček P. Role of family D ATP-binding cassette transporters (ABCD) in cancer. Biochem Soc Trans. 2015;43(5):937-942.

    Codedication to IGA13679-4 and SZU (NIPH, 75010330)

  18. Petr Hodek, Johana Hrdinova, Iva Macova, Pavel Soucek 2, Iveta Mrizova, Kamila Burdova , Rene Kizek , Jiri Hudecek , Marie Stiborova. Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450. Neuroendocrinology Letters 2015, 36, 101-108

    codedication grant MH CZ - DRO (NIPH, 75010330)

  19. Marie Stiborova, František Barta · Katerina Levova, Petr Hodek, Eva Frei, Volker M.

    Arlt , Heinz H. Schmeiser. The infuence of ochratoxin A on DNA adduct for mation

    by the carcinogen ar istolochic acid in rats.   Arch Toxicol 2015; 89:2141–2158

    co-dedication to GAUK

  20. Zdislava Bostikova, Michaela Moserova, Petr Pavek, Marie Stiborova, Petr Hodek. Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation. Neuroendocrinology Letters 2015; 36, 101-107 exclusive dedication

  21. Frantisek Barta, Katerina Levova , Petr Hodek ,Heinz H. Schmeiser , Volker M. Arlt , Marie Stiborova. The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy. Neuroendocrinology Letters 2015; 36 suppl 101-109

    Codedication to GAUK

  22. Martin Ambrož, Iva Boušová , Adam Skarka , Veronika Hanušová 2, Věra Králová ,

    Petra Matoušková , Barbora Szotáková and Lenka Skálová. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells. Molecules 2015, 20, 15343-15358  codedication to GAUK and SVV

  23. Hana Bartikova, Lenka Skalova, Katerina Valentova, Petra Matouskova, Barbora Szotakova, Jan Martin, Vojtech Kvita, Iva Bousova. Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo. Acta Pharm. 65 (2015) DOI: 10.1515/acph-2015-0007

    Codedication to European Social Fund

  24. Petra Matousková, Hana Bártíková, Iva Bousová, Lucie Levorová, Barbora Szotáková,

    and Lenka Skálová. Drug-Metabolizing and Antioxidant Enzymes in Monosodium

    L-Glutamate Obese Mice.  Drug Metab Dispos, 2015; 43:258–265,

    Codedication to Europiean Social Fund

  25. Alejandro Carazo and Petr Pávek. The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists. Sensors 2015;, 15, 9265-9276

    Codedication to SVV

  26. Tomas Smutny , Jurjen Duintjer Tebbens , Petr Pavek. Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 ‘‘missing heritability’’ enigma. Journal of Applied Biomedicine 2015, 13, 181-188.

    Codedication to student project

  27. Alejandro Carazo Fernández , Tomas Smutny , Lucie Hyrsová, Karel Berka, Petr Pavek. Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR). Toxicology Letters 2015; 233, 68–77

      exclusive dedication

2014

 

  1. Matoušková P., Bártíková H., Boušová I., Szotáková B., Martin J., Skorkovská J., Hanušová V., Tománková V., Anzenbacherová E., Lišková B., Anzenbacher P., Skálová L. Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo. Journal of Functional Foods 2014, 10:327–335. (IF 4,480) ED

 

  1. Vrba J., Papouskova B., Pyszkova M., Zatloukalova M., Lemr K., Ulrichova J., Vacek J. Metabolism of palmatine by human hepatocytes and recombinantcytochromes P450. Journal of Pharmaceutical and Biomedical Analysis 2015, 102:193-198. (IF 2,829) ED

 

  1. Vanco J., Sindelar Z., Dvorak Z. Travnicek Z. Iron-salophen complexes involving azole-derived ligands: A new group of compounds with high-level and broad-spectrum in vitro antitumor activity. J Inorg Biochem 2015, 142:92-100. (IF 3,274) ED

 

  1. Anzenbacher P, Marchal S, Palacký J, Anzenbacherová E, Domaschke T, Lange R, Shimizu T, Kitanishi K, Stranava M, Stiborová M, Martinkova M. Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibility. FEBS J 2014, 281(23):5208-5219. (IF 3,986) ED

 

  1. Říha M, Karlíčková J, Filipský T, Macáková K, Rocha L ,Bovicelli P, Proietti Silvestri I, Saso L, Jahodář L, Hrdina R&Mladěnka P. In vitro evaluation of copper-chelating properties of flavonoids. RSC Adv 2014; 4(62):32628-32638 (IF 3.7) ED

 

  1. Mladěnka P, Hrdina R, Filipský T, Říha M & Palicka V. Highly Linear Relationship Betweenthe Dose of Quercetin and the Pharmacological Effect Possible?—A Comment on Liu,et al. Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-TreatedRats. Molecules 2012,17,4281–4291. Molecules 2014,19(7),9606-9609 (IF 2.4) ED

 

  1. Říha M, Vopršalová M, Pilařová V, Semecký V, Holečková M, Vávrová J, Palicka V, Filipský T, Hrdina R, Nováková L&Mladěnka P. Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity. Naunyn Schmiedebergs Arch Pharmacol 2014;387:823-35 (IF 2.1) ED

 

  1. Matoušková P., Bártíková H., HanušováV., Boušová I., Szotáková B., Skálová L. Reference genes for Real-Time PCR quantification of messenger RNAs and microRNAs in mouse model of obesity. PLOS One 2014, 9: e86033 (IF 3.73) ED

 

  1. Langhasová, L., Hanušová, V., Rezek, J., Štohanslová, B., Ambrož M., Králová, V., Vaněk T., DongLoud, J., Yang, J., Skálová L. Essential oil from Myricarubra (Sieb. et Zucc) leaves inhibits cancer cell proliferation and induces apoptosis in several human intestinal lines. Industrial Crops and Products, 2014, 59: 20-26 (IF 3.21) ED

 

  1. Rudolfová, P., Hanušová, V., Skálová, L., Bártíková, H., Matoušková, P., Boušová, I. Effect of selected catechinson doxorubicin antiproliferative efficacy and hepatotoxicity in vitro. Acta Pharmaceutica  2014, 64: 199-209 (IF1.03) ED

 

  1. Bártíková H., Boušová, I., Jedličková, P., Lněničková, K., Skálová, L., Szotáková, B. Effect of Standardized Cranberry Extracton the Activityand Expression of Selected Biotransformation Enzymes in RatLiver and Intestine. Molecules 2014, 19 :14948-14960 (IF 2.1) ED

 

  1. Landa, P., Skálová, L., Boušová, I., Kutil, Z., Langhasová, L., Lou, J.D., Vaněk, T. In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb. Pak. J. Pharm. Sci., 2014, 27: 103-106 (IF 0.95) ED

 

  1. Srovnalova A., Svecarova M., Kopecna-Zapletalova M., Anzenbacher P., Bachleda P., Anzenbacherova E., Dvorak Z. Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9 and CYP3A4 in primary human hepatocytes and human liver microsomes. Journal of Agricultural and Food Chemistry, 2014, ;62(3):789-97  (IF 3,107) ED

 

  1. Stiborová M, Bárta F, Levová K, Hodek P, Frei E, Arlt VM, Schmeiser HH.: The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats. Arch Toxicol. 2014 (DOI: 10.1007/s00204-014-1360-1). IF2013 = 5.078 ED

 

  1. Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M.: Effect of dihydromyricetin on benzo[a]pyrene activation in rats. Neuro Endocrinol Lett. 2014 (in press). IF2013 = 0.935 ED

 

  1. Stiborová M, Schmeiser HH, Frei E, Hodek P, Martínek V.: Enzymes oxidizing the non-aminoazo dye 1-phenylazo-2-naphthol (Sudan I) and their contribution to its genotoxicity and carcinogenicity. Curr Drug Metab. 2014 (in press). IF2013 = 3.487 ED

 

  1. Dvorak Z. Anthocyanidins pelargonidin and cyanidin reduce genotoxic stress in mice - possible involvement of aryl hydrocarbon receptor in the process. Environ Toxicol Pharmacol 2014, 37:1129-1130. (IF 1,862) ED

 

  1. Vavříková E., Vacek J, Valentová K., Marhol P., Ulrichová J., Kuzma M., Křen V. Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers. Molecules 2014 19:4115-4134. (IF 2,095) ED

 

  1. Valentová K., Vrba J., Banciřová M., Ulrichová J., Křen V. Isoquercetrin: Pharmacology, toxicology and metabolism. Food Chem Toxicol 2014 68:267-282. (IF 2,610) ED

 

  1. Matuskova Z, Anzenbacherova E, Vecera R, Tlaskalova-Hogenova H, Kolar M, Anzenbacher P. Administration of a probiotic can change drug pharmacokinetics: effect of E. coli Nissle 1917 on amidarone absorption in rats. PLoS One 2014 9(2):e87150 (IF 3,534) více dedikací

  

  1. Dvorak Z., Srovnalova A., Svecarova M., Vrzal R. (2014) The effect of anthocyans on the expression of selected phase II xenobiotic-metabolizing enzymes in primary cultures of human hepatocytes. Food & Function 5:2145-2151 (IF 2,907) ED

 

  1. Michal Bitman, Radim Vrzal, Zdenek Dvorak, Petr Pavek. Valproate activates ERK signaling pathway in primary human hepatocytes. Biomed Pap Med. 2014; 158(1):39-43.(IF 1,661) ED

 

  1. Riha J., Brenner S., Srovnalova A., Klameth L., Dvorak Z., Jager W., Thalhammer T. (2015) Effects of anthocyans on the expression of organic anion transporting polypeptides (OATPs) in primary human hepatocytes.  Food & Function (in press) (IF2013 2,907) ED

 

  1. Valentova, Katerina; Vrba, Jiri; Bancirova, Martina; et al. Isoquercitrin: Pharmacology, toxicology, and metabolism. Food and Chemical Toxicology,  Vol. 68, 267-282, 2014 (IF 2,61) 2 dedikace GAČR

 

  1. Vavříková E., Vacek J, Valentová K., Marhol P., Ulrichová J., Kuzma M., Křen V. Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers. Molecules  2014 19: 4,  4115-4134 (IF 2,095) ED

 

  1. Kunická T, Souček P. Importance of ABCC1 for cancer therapy and prognosis. Drug Metab Rev. 2014; 46(3):325-342. (IF 6,286) ED

 

  1. Kunická T, Václavíková R, Hlaváč V, Vrána D, Pecha V, Rauš K, Trnková M, Kubáčková K, Ambruš M, Vodičková L, Vodička P, Souček P. Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer. Plos One 2014;9(7):e101740. (IF 3,534) ED

 

  1. Kosztyu P, Dolezel P, Vaclavikova R, Mlejnek P. Can the assessment of ABCB1 gene expression predict its function in vitro? Eur J Haematol. 2014 Oct 16. doi: 10.1111/ejh.12470. (IF 2,414) ED

 

  1. Matoulková P, Pávek P, Malý J, Vlček J. Expert Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction. Opin Drug Metab Toxicol. 2014 10(3):425-35. (IF 2,934) ED

 

  1. Bártíková H., Skálová L., Valentová K., Matoušková P., Szotáková B., Martin J., Kvita V., Boušová  I. Effect of defined green tea extract in various dosage schemes on antioxidant status of mice in vivo. Acta Pharmaceutica - in press (IF 1,025)

 

2013

 

  1. Szotáková, B., Bártíková, H., Hlaváčová, J., Boušová, I., Skálová, L. Inhibitory effect of anthocyanidins on hepatic glutathione S-transferases, UDP-glucuronosyltransferases and carbonyl reductases activities in rat and human. Xenobiotica 43 (2013) 445-452  ED

 

  1. Vyskočilová, E., Szotáková, B., Skálová, L., Bártíková, H., Hlaváčová, J., Boušová, I. Age-related changes in hepatic activity and expression of detoxification enzymes in male rats. BioMed Research International (2013), art. no. 408573 ED

 

  1. Volková, M., Forstová-Křížová, V., Skálová, L., Trejtnar, F. Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 intestinal HCT-8 Cells. Phytotherap. Res 27 (2013) 1889-1893 ED

 

  1. Bártíková, H., Skálová, L., Dršata, J., Boušová, I.: Interaction of anthocyanins with drug-metabolizing enzymes and antioxidant enzymes. Curr. Med. Chem. 20 (2013) 4665-4679  ED

 

  1. Hodek P., Trefil P., Simunek J., Hudecek J., Stiborova M.: Optimized Protocol of Chicken Antibody (IgY) Purification Providing Electrophoretically Homogenous Preparations. Int. J. Electrochem. Sci., 8, 113-124 (2013). IF2011 = 3.729 ED

 

  1. Hodek P., Koblihová J., Kizek R., Frei E., Arlt V.M., Stiborová M.: The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat: Environ. Toxicol. Pharmacol., 36, 989-996 (2013). IF2012 = 2.005 ED

 

  1. Stiborová M., Dračínská H., Martínek V., Svášková D., Hodek P., Milichovský J., Hejduková Ž., Brotánek J., Schmeiser H.H., Frei E.: Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I). Chem. Res. Toxicol., 26, 290-299 (2013). IF2012 = 3.667 ED

 

  1. Macova I., Krizkova J., Frankova J., Stiborova M., Hodek P.: Keratin Cross-reactivity in Electro-transfer (Western blot): How to Suppress It. Int. J. Electrochem. Sci., 8, 1551-1558 (2013). IF2011 = 3.729 ED

 

  1. Smutny T, Mani S, Pavek P. Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily. Curr Drug Metab. 2013 14(10):1059-69. ED

 

  1. Stejskalova, L., Rulcova, A.,Vrzal, R., Dvorak, Z., Pavek, P*.  Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line. Toxicology Letters. 2013, akceptováno IF 3,145 2012   D

 

  1. Rulcova, A.,   Krausova, L., Smutny, T., Vrzal, R., Dvorak, Z., Jover, R., Pavek, P*. Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α up-regulation in primary human hepatocytes.  Pharmacology Reports akceptováno 2013 IF 1,965 2012 D

 

  1. Kamenickova, A., Anzenbacherova, E., Pavek, P., Soshilov, A.A., Denison, M.S., Zapletalova, M., Anzenbacher, P., Dvorak, Z. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicology Letters. 2013, Vol. 221, p. 1-8. IF 3,145 2012  ED
  2. Stejskalova, L., Vrzal, R., Rulcova, A., Dvorak, Z., Pavek, P*. Effects of glucocorticoids on cytochrome P450 1A1 (CYP1A1) expression in isolated human placental trophoblast Journal of Applied Biomedicine. 2013, Vol. 11, p. 163-172 IF0,978 2012  ED

 

  1. Kamenickova A., Anzenbacherova E., Pavek P., Soshilov A.A., Denison M.S., Anzenbacher P., Dvorak Z. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicology Letters. 2013, vol. 218(3), p. 253-259. IF 3,145 2012 ED

 

  1. Hirsova, P., Karlasova, G., Dolezelova, E., Cermanova, J., Zagorova, M., Kadova, Z., Hroch, M., Sispera, L., Tomsik, P., Lenicek, M., Vitek, L., Pavek P., Kucera, O., Cervinkova, Z., Micuda, S. Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2. Toxicology. 2013;303:9-15. IF 4,017 2012 D

 

  1. Belic A., Toth K., Vrzal R., Temesvari M., Porrogi P., Orban E., Rozman D., Dvorak Z., Monostory K. Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor. Chemico-Biological Interactions, 2013, 203(3), 597-603    ED

 

  1. Vrzal R., Frauenstein K., Proksch P., Abel J., Dvorak Z., Haarmann-Stemmann T. Khellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cells. PLoS ONE, 2013, 8(9), e74917  ED

 

  1. Dvorak Z., Novotna A., Vanco J., Travnicek Z. Influence of gold(I) complexes involving adenine derivatives on major drug-drug interaction pathway. Toxicology In Vitro, 2013, 27, 2331-2334   ED

 

  1. Valentová K, Vidlář A, Zatloukalová M, Stuchlík M, Vacek J, Simánek V, Ulrichová J. Biosafety and antioxidant effects of abeverage containing silymarin and arginine. A pilot, human intervention cross-over trial. Food and Chemical Toxicology, 2013, 56C, 178-183  ED

 

  1. Heinrich J, Valentová K, Vacek J, Palíková I, Zatloukalova M, Kosina P, Ulrichová J, Vrbková J, Simánek V. Metabolic Profiling of Phenolic Acids and Oxidative Stress Markers after Consumption of Lonicera caerulea L. Fruit. Journal of Agricultural and Food Chemistry, 2013, 26, 4526-4532  ED

 

  1. Zapletalova M., Vanduchova A., Spicakova A., Anzenbacherova E., Anzenbacher P. Interaction of anthocyanins with human liver microsomal cytochromes P450. Biomedical Papers, 2013, 157(Suppl 1), S56-S59 ED

 

  1. Hlaváč V, Brynychová V, Václavíková R, Ehrlichová M, Vrána D, Pecha V, Koževnikovová R, Trnková M, Gatěk J, Kopperová D, Gut I, Souček P. The expression profile of ABC transporter genes in breast carcinoma. Pharmacogenomics 2013; 14(5):515-29. IF2012 = 3.857 ED

 

  1. Doricakova A, Novotna A, Vrzal R, Pavek P, Dvorak Z. The role of residues T248, Y249 and T422 in the function of human pregnane X receptor. Arch Toxicol. 2013 87:291–301.ED

 

  1. Kamenickova A, Pecova M, Bachleda P, Dvorak Z. Effects of artificial sweeteners on the AhR- and GR-dependent CYP1A1expression in primary human hepatocytes and human cancer cells. Toxicology in Vitro 27 (2013) 2283–2288 IF2013=3,207 ED

 

2012

 
(EGD) Dvorak Z. A paradigm for AhR-mediated alleviation of type 1 diabetes mellitus pathology by isoquinoline alkaloid Berberce. Food Chemistry, 2012; 133 1671–2.
 
(EGD) Boušova I and Skalova L. Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological
consequences Drug Metabolism Reviews, 2012;44(4):267-86.
 
(EGD) Naiman K, Dracínský M, Hodek P, Martínková M, Schmeiser HH, Frei E, Stiborová M. Formation, persistence, and identification of DNA adducts formed by the carcinogenic environmental pollutant o-anisidine in rats. Toxicol Sci. 2012;127(2):348-59.
 
(EGD) Dvořák Z, Starha P, Sindelář Z, Trávníček Z. Evaluation of in vitro cytotoxicity of one-dimensional chain [Fe(salen)(L)](n) complexes against human cancer cell lines. Toxicol In Vitro. 2012;26(3):480-4

(EGD) Macáková K, Mladěnka P, Filipský T, Říha M, Jahodář L, Trejtnar F, Bovicelli P, Proietti Silvestri I, Hrdina R, Saso L. Iron reduction potentiates hydroxyl radical formation only in flavonols. Food Chem. 2012;135(4):2584-92.

(EGD) Macáková K, Řeháková Z, Mladěnka P, Karlíčková J, Filipský T, Říha M, Prasad AK, Parmar VS, Jahodář L, Pávek P, Hrdina R, Saso L. In vitro platelet antiaggregatory properties of 4-methylcoumarins. Biochimie. 2012 ;94(12):2681-6.

(GD) Boušova I, Hajek J, Dršata J, and Skalova L. Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase Xenobiotica, 2012; 2012;42(9):872-9.
 
(GD) Kamenickova A, Dvorak Z. Effects of flavored mineral waters on AhR-CYP1A1 signaling pathway in primary human hepatocytes and in human hepatic and intestinal cancer cells. Food Chem Toxicol. 2012; 50(6):1933-9
 
(GD) Jakubec P, Bancirova M, Halouzka V, Lojek A, Ciz M, Denev P, Cibicek N, Vacek J, Vostalova J, Ulrichova J, Hrbac J. Electrochemical sensing of total antioxidant capacity and polyphenol content in wine samples using amperometry online-coupled with microdialysis. J Agric Food Chem. 2012;60(32):7836-43.

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