Selected Papers of the Research Team Members

2016

  • Adamcova M, Popelova-Lencova O, Jirkovsky E, Simko F, Gersl V and Sterba M (2016) Cardiac troponins--Translational biomarkers in cardiology: Theory and practice of cardiac troponin high-sensitivity assays. BioFactors (Oxford, England) 42:133-148. IF (2015) = 4.504

  • Cidlina A, Svec J, Ludvova L, Kunes J, Zimcik P and Novakova V (2016) Predominant effect of connecting atom and position of substituents on azomethine nitrogens' basicity in phthalocyanines. J Porphyr Phthalocya 20:1122-1133. IF (2015) = 1.087

  • Donzello MP, Ercolani C, Novakova V, Zimcik P and Stuzhin PA (2016) Tetrapyrazinoporphyrazines and their metal derivatives. Part I: Synthesis and basic structural information. Coordination Chemistry Reviews 309:107-179. IF (2015) = 12.994

  • Haskova P, Jansova H, Bures J, Machacek M, Jirkovska A, Franz KJ, Kovarikova P and Simunek T (2016) Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. Toxicology 371:17-28. IF (2015) = 3.817

  • Hruskova K, Potuckova E, Hergeselova T, Liptakova L, Haskova P, Mingas P, Kovarikova P, Simunek T and Vavrova K (2016) Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications. Eur J Med Chem 120:97-110. IF (2015) = 3.902

  • Jansova H, Bures J, Machacek M, Haskova P, Jirkovska A, Roh J, Wang Q, Franz KJ, Kovarikova P and Simunek T (2016) Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. Toxicology 350-352:15-24. IF (2015) = 3.817

  • Jezkova K, Rathouska J, Nemeckova I, Fikrova P, Dolezelova E, Varejckova M, Vitverova B, Tysonova K, Serwadczak A, Buczek E, Bernabeu C, Lopez-Novoa JM, Chlopicki S and Nachtigal P (2016) High Levels of Soluble Endoglin Induce a Proinflammatory and Oxidative-Stress Phenotype Associated with Preserved NO-Dependent Vasodilatation in Aortas from Mice Fed a High-Fat Diet. Journal of vascular research 53:149-162. IF (2015) = 2.186

  • Karabanovich G, Zemanová J, Smutný T, Székely R, Šarkan M, Centárová I, Vocat A, Pávková I, Čonka P, Němeček J, Stolaříková J, Vejsová M, Vávrová K, Klimešová V, Hrabálek A, Pávek P, Cole ST, Mikušová K and Roh J (2016) Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-Oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. J Med Chem 59:2362−2380. IF (2015) = 5.589

  • Karlickova J, Riha M, Filipsky T, Macakova K, Hrdina R and Mladenka P (2016) Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway. Planta Med 82:76-83. IF (2015) = 1.990

  • Kováčik A, Opálka L, Šilarová M, Roh J and Vávrová K (2016) Synthesis of 6-hydroxyceramide using ruthenium-catalyzed hydrosilylation–protodesilylation. Unexpected formation of a long periodicity lamellar phase in skin lipid membranes. RSC Adv 6:73343-73350. IF (2015) = 3.289

  • Lenco J, Lencova-Popelova O, Link M, Jirkovska A, Tambor V, Potuckova E, Stulik J, Simunek T and Sterba M (2016) Corrigendum to: "Proteomic investigation of embryonic rat heart-derived H9c2 cell line sheds new light on the molecular phenotype of the popular cell model" [Exp. Cell Res. 339 2 (2015) 174-186]. Experimental cell research 343:267. IF (2015) = 3.378

  • Lencova-Popelova O, Jansova H, Jirkovsky E, Bures J, Jirkovska-Vavrova A, Mazurova Y, Reimerova P, Vostatkova L, Adamcova M, Hroch M, Pokorna Z, Kovarikova P, Simunek T and Sterba M (2016) Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings? Toxicology 372:52-63. IF (2015) = 3.817

  • Lencova-Popelova O, Jirkovsky E, Jansova H, Jirkovska-Vavrova A, Vostatkova-Tichotova L, Mazurova Y, Adamcova M, Chladek J, Hroch M, Pokorna Z, Gersl V, Simunek T and Sterba M (2016) Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane. Journal of molecular and cellular cardiology 91:92-103. IF (2015) = 4.874

  • Lochman L, Svec J, Roh J, Kirakci K, Lang K, Zimcik P and Novakova V (2016) Metal-Cation Recognition in Water by a Tetrapyrazinoporphyrazine-Based Tweezer Receptor. Chemistry-a European Journal 22:2417-2426. IF (2015) = 5.771

  • Machacek M, Demuth J, Cermak P, Vavreckova M, Hruba L, Jedlickova A, Kubat P, Simunek T, Novakova V and Zimcik P (2016) Tetra(3,4-pyrido)porphyrazines Caught in the Cationic Cage: Toward Nanomolar Active Photosensitizers. Journal of Medicinal Chemistry 59:9443-9456. IF (2015) = 5.589

  • Machacek M, Kollar J, Miletin M, Kucera R, Kubat P, Simunek T, Novakova V and Zimcik P (2016) Anionic hexadeca-carboxylate tetrapyrazinoporphyrazine: synthesis and in vitro photodynamic studies of a water-soluble, non-aggregating photosensitizer. RSC Advances 6:10064-10077. IF (2015) = 3.289

  • Martin J, Mladenka P, Saso L and Kostova I (2016) Lanthanide(III) complexes are more active inhibitors of the Fenton reaction than pure ligands. Redox Rep 21:84-89. IF (2015) = 2.606

  • Mladenka P, Riha M, Martin J, Gorova B, Matejicek A and Spilkova J (2016) Fruit extracts of 10 varieties of elderberry (Sambucus nigra L.) interact differently with iron and copper. Phytochem Lett 18:232-238. IF (2015) = 1.353

  • Najmanova I, Pourova J, Voprsalova M, Pilarova V, Semecky V, Novakova L and Mladenka P (2016) Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats. Mol Nutr Food Res 60:981-991. IF (2015) = 4.551

  • Opalka L, Kovacik A, Maixner J and Vavrova K (2016) Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability. Langmuir 32:12894-12904. IF (2015) = 3.993

  • Riha M, Haskova P, Martin J, Filipsky T, Vanova K, Vavrova J, Holeckova M, Homola P, Vitek L, Palicka V, Simunek T and Mladenka P (2016) Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury. Oxid Med Cell Longev 2016:5213532. IF (2015) = 4.492

  • Roh J, Karabanovich G, Novakova V, Simunek T and Vavrova K (2016) Large-Scale Synthesis of Piperazine-2,6-dione and Its Use in the Synthesis of Dexrazoxane Analogues. Synthesis 48:4580-4588. IF (2015) = 2.652

  • Sestak V, Roh J, Klepalova L and Kovarikova P (2016) A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor. J Pharm Biomed Anal 124:365-373. IF (2015) = 3.169

  • Skolova B, Janusova B and Vavrova K (2016) Ceramides with a pentadecasphingosine chain and short acyls have strong permeabilization effects on skin and model lipid membranes. Biochim Biophys Acta 1858:220-232. IF (2015) = 3.687

  • Tycova A, Vido M, Kovarikova P and Foret F (2016) Interface-free capillary electrophoresis-mass spectrometry system with nanospray ionization-Analysis of dexrazoxane in blood plasma. J Chromatogr A 1466:173-179. IF (2015) = 3.926

  • Vavrova K (2016) Emerging small-molecule compounds for treatment of atopic dermatitis: a review. Expert Opin Ther Pat 26:21-34. IF (2015) = 4.626

  • Zoschke C, Ulrich M, Sochorova M, Wolff C, Vavrova K, Ma N, Ulrich C, Brandner JM and Schafer-Korting M (2016) The barrier function of organotypic non-melanoma skin cancer models. J Control Release 233:10-18. IF (2015) = 7.441

     

 

2015

  • Adamcova M, Lencova-Popelova O, Jirkovsky E, Mazurova Y, Palicka V, Simko F, Gersl V and Sterba M (2015) Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value. International journal of cardiology 201:358-367. IF (2015) = 4.638

  • Bures J, Jansova H, Stariat J, Filipsky T, Mladenka P, Simunek T, Kucera R, Klimes J, Wang Q, Franz KJ and Kovarikova P (2015) LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). J Pharm Biomed Anal 105:55-63. IF (2015) = 2.979

  • Cidlina A, Novakova V, Miletin M and Zimcik P (2015) Peripheral substitution as a tool for tuning electron-accepting properties of phthalocyanine analogs in intramolecular charge transfer. Dalton T 44:6961-6971. IF (2015) = 4.177

  • Cidlina A, Pausimova Z, Miletin M, Zimcik P and Novakova V (2015) The effect of substitutents at alkylsulfanyl/arylsulfanyl non-peripherally substituted phthalocyanines: Spectral and photophysical properties, basicity and photostability. J Porphyr Phthalocya 19:1095-1106. IF (2015) = 1.087

  • Filipsky T, Riha M, Macakova K, Anzenbacherova E, Karlickova J and Mladenka P (2015) Antioxidant effects of coumarins include direct radical scavenging, metal chelation and inhibition of ROS-producing enzymes. Curr Top Med Chem 15:415-431. IF (2015) = 2.900

  • Jirkovská-Vávrová A, Roh J, Lenčová-Popelová O, Jirkovský E, Hrušková K, Potůčková-Macková E, Jansová H, Hašková P, Martinková P and Eisner T (2015) Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo. Toxicol Res 4:1098-1114. IF (2015) = 2.161

  • Karabanovich G, Roh J, Soukup O, Pávková I, Pasdiorová M, Tambor V, Stolaříková J, Vejsová M, Vávrová K, Klimešová V and Hrabálek A (2015) Tetrazole Regioisomers in the Development of Nitro Group-Containing Antitubercular Agents. Med Chem Commun 6:174-181. IF (2015) = 2.319

  • Karlickova J, Macakova K, Riha M, Pinheiro LM, Filipsky T, Hornasova V, Hrdina R and Mladenka P (2015) Isoflavones Reduce Copper with Minimal Impact on Iron In Vitro. Oxid Med Cell Longev 2015:437381. IF (2015) = 4.492

  • Lenco J, Lencova-Popelova O, Link M, Jirkovska A, Tambor V, Potuckova E, Stulik J, Simunek T and Sterba M (2015) Proteomic investigation of embryonic rat heart-derived H9c2 cell line sheds new light on the molecular phenotype of the popular cell model. Experimental cell research 339:174-186. IF (2015) = 3.378

  • Lochman L, Svec J, Roh J and Novakova V (2015) The role of the size of aza-crown recognition moiety in azaphthalocyanine fluorescence sensors for alkali and alkaline earth metal cations. Dyes and Pigments 121:178-187. IF (2015) = 4.055

  • Machacek M, Cidlina A, Novakova V, Svec J, Rudof E, Miletin M, Kucera R, Simunek T and Zimcik P (2015) Far-Red-Absorbing Cationic Phthalocyanine Photosensitizers: Synthesis and Evaluation of the Photodynamic Anticancer Activity and the Mode of Cell Death Induction. Journal of Medicinal Chemistry 58:1736-1749. IF (2015) = 5.589

  • Makhseed S, Ghazal B, Abdelmoniem AM, Novakova V and Zimcik P (2015) Photophysical and theoretical studies of peripherally halogenated octaphenoxyphthalocyanines. RSC Advances 5:58854-58864. IF (2015) = 3.289

  • Najmanova I, Dosedel M, Hrdina R, Anzenbacher P, Filipsky T, Riha M and Mladenka P (2015) Cardiovascular effects of coumarins besides their antioxidant activity. Curr Top Med Chem 15:830-849. IF (2015) = 2.900

  • Necedova M, Magdolen P, Novakova V, Cigan M, Vlckova S, Zahradnik P and Fulopova A (2015) Synthesis and Photophysical, Electrochemical and Theoretical Study of Thiazole-Annelated Phthalocyanines. Eur J Org Chem:7053-7068. IF (2015) = 3.068

  • Nemeckova I, Serwadczak A, Oujo B, Jezkova K, Rathouska J, Fikrova P, Varejckova M, Bernabeu C, Lopez-Novoa JM, Chlopicki S and Nachtigal P (2015) High soluble endoglin levels do not induce endothelial dysfunction in mouse aorta. PLoS One 10:e0119665. IF (2015) = 3.057

  • Novakova V, Laskova M, Vavrickova H and Zimcik P (2015) Phenol-Substituted Tetrapyrazinoporphyrazines: pH-Dependent Fluorescence in Basic Media. Chemistry-A European Journal 21:14382-14392. IF (2015) = 5.771

  • Novakova V, Reimerova P, Svec J, Suchan D, Miletin M, Rhoda HM, Nemykin VN and Zimcik P (2015) Systematic investigation of phthalocyanines, naphthalocyanines, and their aza-analogues. Effect of the isosteric aza-replacement in the core. Dalton T 44:13220-13233. IF (2015) = 4.177

  • Opalka L, Kovacik A, Sochorova M, Roh J, Kunes J, Lenco J and Vavrova K (2015) Scalable Synthesis of Human Ultralong Chain Ceramides. Org Lett 17:5456-5459. IF (2015) = 6.732

  • Paloncyova M, Vavrova K, Sovova Z, DeVane R, Otyepka M and Berka K (2015) Structural Changes in Ceramide Bilayers Rationalize Increased Permeation through Stratum Corneum Models with Shorter Acyl Tails. J Phys Chem B 119:9811-9819. IF (2015) = 3.187

  • Potuckova E, Roh J, Machacek M, Sahni S, Stariat J, Sestak V, Jansova H, Haskova P, Jirkovska A, Vavrova K, Kovarikova P, Kalinowski DS, Richardson DR and Simunek T (2015) In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites. PLoS One 10:e0139929. IF (2015) = 3.057

  • Rathouska J, Jezkova K, Nemeckova I and Nachtigal P (2015) Soluble endoglin, hypercholesterolemia and endothelial dysfunction. Atherosclerosis 243:383-388. IF (2015) = 3.942

  • Rathouska J, Jezkova K, Nemeckova I, Zemankova L, Varejckova M and Nachtigal P (2015) Endoglin is not expressed with cell adhesion molecules in aorta during atherogenesis in apoE-deficient mice. Histology and histopathology 30:233-244. IF (2015) = 1.875

  • Rathouska J, Nemeckova I, Zemankova L, Strasky Z, Jezkova K, Varejckova M and Nachtigal P (2015) Cell adhesion molecules and eNOS expression in aorta of normocholesterolemic mice with different predispositions to atherosclerosis. Heart and vessels 30:241-248. IF (2015) = 2.293

  • Sestak V, Stariat J, Cermanova J, Potuckova E, Chladek J, Roh J, Bures J, Jansova H, Prusa P, Sterba M, Micuda S, Simunek T, Kalinowski DS, Richardson DR and Kovarikova P (2015) Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents. Oncotarget 6:42411-42428. IF (2015) = 5.008

  • Stahlberg S, Skolova B, Madhu PK, Vogel A, Vavrova K and Huster D (2015) Probing the role of the ceramide acyl chain length and sphingosine unsaturation in model skin barrier lipid mixtures by (2)H solid-state NMR spectroscopy. Langmuir 31:4906-4915. IF (2015) = 3.993

  • Svec J, Zimcik P, Novakova L, Rakitin OA, Amelichev SA, Stuzhin PA and Novakova V (2015) 1,2,5-Chalcogenadiazole-Annulated Tripyrazinoporphyrazines: Synthesis, Spectral Characteristics, and Influence of the Heavy Atom Effect on Their Photophysical Properties. Eur J Org Chem:596-604. IF (2015) = 3.068

  • Vachova L, Machacek M, Kucera R, Demuth J, Cermak P, Kopecky K, Miletin M, Jedlickova A, Simunek T, Novakova V and Zimcik P (2015) Heteroatom-substituted tetra(3,4-pyrido)porphyrazines: a stride toward near-infrared-absorbing macrocycles. Org Biomol Chem 13:5608-5612. IF (2015) = 3.559

  • Wallmeyer L, Lehnen D, Eger N, Sochorova M, Opalka L, Kovacik A, Vavrova K and Hedtrich S (2015) Stimulation of PPARalpha normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin. J Dermatol Sci 80:102-110. IF (2015) = 3.739

  • Witting M, Boreham A, Brodwolf R, Vavrova K, Alexiev U, Friess W and Hedtrich S (2015) Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules. Mol Pharm 12:1391-1401. IF (2015) = 4.342

  • Zemankova L, Varejckova M, Dolezalova E, Fikrova P, Jezkova K, Rathouska J, Cerveny L, Botella LM, Bernabeu C, Nemeckova I and Nachtigal P (2015) Atorvastatin-induced endothelial nitric oxide synthase expression in endothelial cells is mediated by endoglin. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 66:403-413. IF (2015) = 2.804

 

2014

  • Cermanova J, Kadova Z, Dolezelova E, Zagorova M, Safka V, Hroch M, Laho T, Holeckova M, Mokry J, Kovarikova P, Bures J, Sterba M and Micuda S (2014) Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats. Shock 42:372-379. IF (2014) = 3.045

  • Diblikova D, Kopecna M, Skolova B, Krecmerova M, Roh J, Hrabalek A and Vavrova K (2014) Transdermal delivery and cutaneous targeting of antivirals using a penetration enhancer and lysolipid prodrugs. Pharm Res 31:1071-1081. IF (2014) = 3.420

  • Jansova H, Machacek M, Wang Q, Haskova P, Jirkovska A, Potuckova E, Kielar F, Franz KJ and Simunek T (2014) Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. Free Radic Biol Med 74:210-221. IF (2014) = 5.736

  • Karabanovich G, Roh J, Smutny T, Nemecek J, Vicherek P, Stolarikova J, Vejsova M, Dufkova I, Vavrova K, Pavek P, Klimesova V and Hrabalek A (2014) 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. Eur J Med Chem 82:324-340. IF (2014) = 3.447

  • Kovacik A, Roh J and Vavrova K (2014) The Chemistry and Biology of 6-Hydroxyceramide, the Youngest Member of the Human Sphingolipid Family. ChemBioChem 15:1555-1562. IF (2014) = 3.088

  • Kucera R, Kovarikova P, Pasakova-Vrbatova I, Slaninova J and Klimes J (2014) Zirconia--a stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography. J Sep Sci 37:1089-1093. IF (2014) = 2.737

  • Lencova-Popelova O, Jirkovsky E, Mazurova Y, Lenco J, Adamcova M, Simunek T, Gersl V and Sterba M (2014) Molecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up. PLoS One 9:e96055. IF (2014) = 3.234

  • Mladenka P, Hrdina R, Filipsky T, Riha M and Palicka V (2014) Is a highly linear relationship between the dose of quercetin and the pharmacological effect possible? - a comment on Liu, et al. Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats. Molecules 2012, 17, 4281-4291. Molecules 19:9606-9609. IF (2014) = 2.416

  • Novakova V, Hladik P, Filandrova T, Zajicova I, Krepsova V, Miletin M, Lenco J and Zimcik P (2014) Structural factors influencing the intramolecular charge transfer and photoinduced electron transfer in tetrapyrazinoporphyrazines. Physical Chemistry Chemical Physics 16:5440-5446. IF (2014) = 4.493

  • Novakova V, Miletin M, Filandrová T, Lenčo J, Růžička A and Zimcik P (2014) Role of Steric Hindrance in the Newman-Kwart Rearrangement and in the Synthesis and Photophysical Properties of Arylsulfanyl Tetrapyrazinoporphyrazines. The Journal of Organic Chemistry 79:2082-2093.  IF (2014) = 4.721

  • Potuckova E, Hruskova K, Bures J, Kovarikova P, Spirkova IA, Pravdikova K, Kolbabova L, Hergeselova T, Haskova P, Jansova H, Machacek M, Jirkovska A, Richardson V, Lane DJ, Kalinowski DS, Richardson DR, Vavrova K and Simunek T (2014) Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties. PLoS One 9:e112059. IF (2014) = 3.234

  • Potuckova E, Jansova H, Machacek M, Vavrova A, Haskova P, Tichotova L, Richardson V, Kalinowski DS, Richardson DR and Simunek T (2014) Quantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugs. PLoS One 9:e88754. IF (2014) = 3.234

  • Pullmannova P, Stankova K, Pospisilova M, Skolova B, Zbytovska J and Vavrova K (2014) Effects of sphingomyelin/ceramide ratio on the permeability and microstructure of model stratum corneum lipid membranes. Biochim Biophys Acta 1838:2115-2126. IF (2014) = 3.836

  • Riha M, Karlickova J, Filipsky T, Jahodar L, Hrdina R and Mladenka P (2014) In vitro copper-chelating properties of flavonoids. Free Radic Biol Med 75 Suppl 1:S46. IF (2014) = 5.736

  • Riha M, Voprsalova M, Pilarova V, Semecky V, Holeckova M, Vavrova J, Palicka V, Filipsky T, Hrdina R, Novakova L and Mladenka P (2014) Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity. Naunyn Schmiedebergs Arch Pharmacol 387:823-835. IF (2014) = 2.471

  • Serda M, Kalinowski DS, Rasko N, Potuckova E, Mrozek-Wilczkiewicz A, Musiol R, Malecki JG, Sajewicz M, Ratuszna A, Muchowicz A, Golab J, Simunek T, Richardson DR and Polanski J (2014) Exploring the anti-cancer activity of novel thiosemicarbazones generated through the combination of retro-fragments: dissection of critical structure-activity relationships. PLoS One 9:e110291. IF (2014) = 3.234

  • Skolova B, Hudska K, Pullmannova P, Kovacik A, Palat K, Roh J, Fleddermann J, Estrela-Lopis I and Vavrova K (2014) Different phase behavior and packing of ceramides with long (C16) and very long (C24) acyls in model membranes: infrared spectroscopy using deuterated lipids. J Phys Chem B 118:10460-10470. IF (2014) = 3.302

  • Skolova B, Jandovska K, Pullmannova P, Tesar O, Roh J, Hrabalek A and Vavrova K (2014) The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes. Langmuir 30:5527-5535. IF (2014) = 4.457

  • Stariat J, Suprunova V, Roh J, Sestak V, Eisner T, Filipsky T, Mladenka P, Nobilis M, Simunek T, Klimes J, Kalinowski DS, Richardson DR and Kovarikova P (2014) Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats. Biomedical chromatography : BMC 28:621-629. IF (2014) = 1.723

  • Vavrova K, Henkes D, Struver K, Sochorova M, Skolova B, Witting MY, Friess W, Schreml S, Meier RJ, Schafer-Korting M, Fluhr JW and Kuchler S (2014) Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct. J Invest Dermatol 134:746-753. IF (2014) = 7.216

 

2013

  • Karabanovich G., Roh J., Padělková Z., Novák Z., Vávrová K., Hrabálek A. (2013): One-pot synthesis of 1-substituted-5-alkylselanyl-1H-tetrazoles from isoselenocyanates: Unexpected formation of N-alkyl-N-arylcyanamides and (Z)-Se-alkyl-N-cyano-N,N’-diarylisoselenoureas. Tetrahedron 69: 8798-8808. DOI: 10.1016/j.tet.2013.07.103; IF2012 = 2.803

  • Vavrová (Jirkovská) A, Jansová H, Macková E, Macháček M, Hašková P, Tichotová L, Štěrba M, Šimůnek T (2013). Catalytic Inhibitors of Topoisomerase II Differently Modulate the Toxicity of Anthracyclines in Cardiac and Cancer Cells. PLoS ONE 8:e76676. doi: 10.1371/journal.pone.0076676. IF2012=3.730

  • Jirkovský E, Lenčová (Popelová) O, Hroch M, Adamcová M, Mazurová Y, Vávrová J, Mičuda S, Šimůnek T, Geršl V, Štěrba M (2013). Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits. Toxicology 311:191-204. doi: 10.1016/j.tox.2013.06.012. IF2012=4.017

  • Štěrba M, Popelová O, Vávrová (Jirkovská) A, Jirkovský E, Kovaříková P, Geršl V, Šimůnek T (2013). Oxidative stress, redox signaling, and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection. Antioxid Redox Signal. 18:899-929. doi: 10.1089/ars.2012.4795. IF2012=7.189

  • Filipský T., Říha M., Hrdina R., Vávrová K., Mladěnka P (2013): Mathematical calculations of iron complex stoichiometry by direct UV-Vis spectrophotometry. Bioorganic Chemistry 49: 1-8. DOI: 10.1016/j.bioorg.2013.06.002 IF2012=1.732

  • Mladěnka P., Zatloukalova L., Filipsky T., Vavrova J., Holeckova M., Palicka V., Hrdina R. (2013): Common biomarkers of oxidative stress do not reflect cardiovascular dysfunction in rats. Biomedical Papers-Olomouc 157:146-152. DOI: 10.5507/bp.2013.033  IF2012=0.990

  • Říha M., Karlíčková J., Filipský T., Macáková K.,  Hrdina R., Mladěnka P. (2013): Novel method for rapid copper chelation assessment confirmed low affinity of D-penicillamine for copper in comparison with trientine and 8-hydroxyquinolines. Journal of Inorganic Biochemistry 123: 80-7. DOI:10.1016/j.jinorgbio.2013.02.011  IF2012= 3.197

  • Suchanek J., Lang K., Novakova V., Zimcik P., Zelinger Z., Kubat P. (2013): Photophysical properties of CdSe quantum dot self-assemblies with zinc phthalocyanines and azaphthalocyanines. Photochemical & Photobiological Sciences 12: 743-750. DOI: 10.1039/C2PP25348H, IF2012 = 2.923

  • Novakova V., Lochman L., Zajícová I., Kopecky K., Miletin M., Lang K., Kirakci K., Zimcik P. (2013): Azaphthalocyanines: Red Fluorescent Probes for Cations. Chemistry – A European Journal 19: 5025-5028. DOI: 10.1002/chem.201300079, IF2012 = 5.831

  • Makhseed S., Machacek M., Alfadly W., Tuhl A., Vinodh M., Simunek T., Novakova V., Kubat P., Rudolf E., Zimcik P. (2013): Water-soluble non-aggregating zinc phthalocyanine and in vitro studies for photodynamic therapy. Chemical Communications 49: 11149-11151. DOI: 10.1039/C3CC44609C, IF2012 = 6.378

  • Stariat J., Kovarikova P., Kucera R., Klimes J., Kalinowski D. S., Richardson D. R., Ketola R. A. (2013): Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry 405: 1651-1661. DOI 10.1007/s00216-012-6562-x, IF2012 = 3.659

  • Strasky Z., Zemankova L., Nemeckova I., Rathouska J., Wong R. J., Muchova L., Subhanova I., Vanikova J., Vanova K., Vitek L., Nachtigal P. (2013): Spirulina platensis and phycocyanobilin activate atheroprotective heme oxygenase-1: a possible implication for atherogenesis. Food & Function 4: 1586-1594. DOI: 10.1039/c3fo60230c, IF2012 = 2.694

  • Stariat J., Suprunova V., Roh J., Sestak V., Eisner T., Filipsky T., Mladenka P., Nobilis M., Simunek T., Klimes J., Kalinowski D. S., Richardson D. R., Kovarikova P. (2013): Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats. Biomedical Chromatography in press: DOI 10.1002/bmc.3080, IF2012 = 1.945

  • Kovarikova P., Pasakova-Vrbatova I., Vavrova A., Stariat J., Klimes J., Simunek T. (2013): Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium. Journal of Pharmaceutical and Biomedical Analysis 76: 243-251. DOI 10.1016/j.jpba.2012.12.024, IF2012=2,947

 

2012

  • Roh J., Vavrova K., Hrabalek A. (2012): Synthesis and Functionalization of 5-Substituted Tetrazoles. European Journal of Organic Chemistry: 6101–6118. DOI: 10.1002/ejoc.201200469; IF2012 = 3.344

  • Stariat J., Sestak V., Vavrova K., Nobilis M., Kollarova Z., Klimes J., Kalinowski D. S., Richardson D. R., Kovarikova P. (2012): LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT. Analytical Bioanalytical Chemistry 403: 309-321. DOI 10.1007/s00216-012-5766-4, IF2012 = 3.659

  • Macková E., Hrušková K., Bendová P., Vávrová A., Jansová H., Hašková P., Kovaříková P., VávrováK., Simunek T. (2012): Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: novel iron chelators with selective antiproliferative action. Chemico-Biological Interactions 197: 69-79. doi: 10.1016/j.cbi.2012.03.010 IF2012 = 2.967

  • Jirkovský E, Lenčová (Popelová) O, Křiváková-Stanková P, Vávrová A, Hroch M, Hašková P, Brčáková-Doleželová E, Mičuda S, Adamcová M, Šimůnek T, Červinková Z, Geršl V, Štěrba M (2012). J Pharmacol Exp Ther. 343:468-78. doi: 10.1124/jpet.112.198358. IF2012=3,891

  • Neckář J, Boudíková A, Mandíková P, Štěrba M, Lenčová (Popelová) O, Mikšík I, Dabrowská L, Mráz J, Geršl V, Kolář F (2012). Protective effects of dexrazoxane against acute ischaemia/reperfusion injury of rat hearts. Can J Physiol Pharmacol. 90:1303-10. doi: 10.1139/y2012-096. IF2012=1,556

  • Macáková K., Řeháková Z., Mladěnka P., Karlíčková J., Filipský T., Říha M., Prasad A.K., Parmar V.S., Jahodář L., Pávek P., Hrdina R., Saso L. (2012): In vitro platelet antiaggregatory properties of 4-methylcoumarins. Biochimie 94: 2681-6. DOI: 10.1016/j.biochi.2012.09.006 IF2012= 3.142

  • Macáková K., Mladěnka P., Filipský T.,  Říha M.,  Jahodář L.,   Trejtnar F.,  Bovicelli P.,  Proietti Silvestri I., Hrdina R.,  Saso L. (2012): Iron reduction potentiates hydroxyl radical formation only in flavonols. Food Chemistry 135: 2584–92. DOI: 10.1016/j.foodchem.2012.06.107  IF2012= 3.334

  • Zatloukalová L., Filipský T., Mladěnka P., Semecký V., Macáková K., Holečková M., Vávrová J., Palicka V. and Hrdina R. (2012): Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity. Canadian Journal of Physiology and Pharmacology 90(4):473-84. DOI: 10.1139/Y2012-009 IF2012= 1.556

  • Filipský T., Zatloukalová L., Mladěnka P., Hrdina R. (2012): Acute initial hemodynamic changes in a rat isoprenaline model of cardiotoxicity. Human & Experimental Toxicology 31: 830–43.  DOI: 10.1177/0960327112438927 IF2012= 1.453

  • Filipský T., Mladěnka P., Macáková K., Hrdina R., Saso L., Marchetti F., Pettinari C. (2012): In vitro characteristics of 1-phenyl-3-methyl-4-acylpyrazol-5-ones iron chelators. Biochimie 94(1):125-31. DOI: 10.1016/j.biochi.2011.09.024 IF2012= 3.142

  • Zimčík P. (2012): Azaftalocyaniny - od syntéz přes fotochemické a fotofyzikální vlastnosti k aplikacím. Chem. Listy 106: 275-282. IF2012 = 0.453

  •  Zimcik P., Novakova V., Kopecky K., Miletin M., Uslu Kobak R. Z., Svandrlikova E., Váchová L., Lang K. (2012): Magnesium Azaphthalocyanines: An Emerging Family of Excellent Red-Emitting Fluorophores. Inorganic Chemistry 51: 4215-4223. DOI: 10.1021/ic2027016, IF2012 = 4.593

  • Vachova L., Novakova V., Kopecky K., Miletin M., Zimcik P. (2012): Effect of intramolecular charge transfer on fluorescence and singlet oxygen production of phthalocyanine analogues. Dalton Transactions 41: 11651-11656. DOI:  10.1039/C2DT31403G, IF2012 = 3.806

  • Tuhl A., Makhseed S., Zimcik P., Al-Awadi N., Novakova V., Samuel J. (2012): Heavy metal effects on physicochemical properties of non-aggregated azaphthalocyanine derivatives. Journal of Porphyrins and Phthalocyanines 16: 817-825. DOI: 10.1142/S1088424612500800, IF2012 = 1.433

  • Novakova V., Roh J., Gela P., Kuneš J., Zimcik P. (2012): Azaphthalocyanines with fused triazolo rings: formation of sterically stressed constitutional isomers. Chemical Communications 48: 4326-4328. DOI:  10.1039/C2CC30942D, IF2012 = 6.378

  • Novakova V., Kobak R. Z. U., Kucera R., Kopecky K., Miletin M., Krepsova V., Ivincova J., Zimcik P. (2012): The effect of the number of carbohydrate moieties on the azaphthalocyanine properties. Dalton Transactions 41: 10596-10604. DOI:  10.1039/C2DT30971H, IF2012 = 3.806

  • Makhseed S., Tuhl A., Samuel J., Zimcik P., Al-Awadi N., Novakova V. (2012): New highly soluble phenoxy-substituted phthalocyanine and azaphthalocyanine derivatives: Synthesis, photochemical and photophysical studies and atypical aggregation behavior. Dyes and Pigments 95: 351-357. DOI: 10.1016/j.dyepig.2012.03.023, IF2012 = 3.532

  • Vávrová A., Šimůnek T. (2012) DNA topoisomerase IIb: A player in regulation of gene expression and cell differentiation. International Journal of Biochemistry & Cell Biology. 44(6): 834-837. DOI: 10.1016/j.biocel.2012.03.005 IF2012 = 4.152

  • Vecerova L., Strasky Z., Rathouska J., Slanarova M., Brcakova E., Micuda S., Nachtigal P. (2012): Activation of TGF-beta receptors and Smad proteins by atorvastatin is related to reduced atherogenesis in ApoE/LDLR double knockout mice. J Atheroscler Thromb 19: 115-126, IF2012 = 2.933

  • Nachtigal P., Zemankova Vecerova L., Rathouska J., Strasky Z. (2012): The role of endoglin in atherosclerosis. Atherosclerosis 224: 4-11. 10.1016/j.atherosclerosis.2012.03.001, IF2012 = 3.706

 

 

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