Methods

1. Subjective methods

Questionnaire surveys and interviews

High-quality instruments

• psychometrically valid
• standard
• readable
• suitable for respondents

Osteoporosis Specific Morisky Medication Adherence Scale (OS-MMAS); Morisky 4-Item Self-Report MEASURE of Medication-taking Behavior (MMAS-4)

2. Prescription-based databases and health services databases

Analyses based on production data from the General Health Insurance Company of the Czech Republic (trends in prescription, drug consumption, primary compliance, health services utilization).

General Health Insurance Company covers more than 60% of the insured people in the Czech Republic and has a major impact on drug policy as well as pricing and reimbursement of various health services including new medical technologies. At present, General Health Insurance Company introduces the principles of pharmacoeconomics and health technology assessment into the evaluation of medical devices and together with the Ministry of Health and the State Institute for Drug Control into the assessment and appraisal of pharmaceuticals.

3. Medication Event Monitoring System (MEMS)

Medication Event Monitoring System (MEMS)

Electronic drug packages designed to measure and analyse compliance of ambulatory patients’ prescribed medications. We have been introducing MEMS into research of patient compliance in the Czech Republic.

1. Faculty of Medicine in Hradec Kralove, Charles University in Prague and University Hospital Hradec Kralove, Czech Republic, Department of Clinical Biochemistry, Osteocentre: Prof. MUDr. Vladimír Palička, CSc., dr.h.c.
2. Pardubice Regional Hospital, Osteoporosis Centre: MUDr. Tomáš Hála