Publications

Publications since 2005

2017

Kastner P., Pilařová P., Nejedlý T., Macháček M., Klimeš J. Stability Indicating Method for Determination of Sodium Picosulfate in Pharmaceutical Preparation – Comparison of HPLC, UHPLC and HTLC, Current Pharmaceutical Analysis, in press (IF2015 = 0,885) DOI: 10.2174/1573412912666160518145632

2016

Lenčová-Popelová O., Jansová H., Jirkovský E., Bureš J., Jirkovská-Vávrová A., Mazurová Y., Reimerová P., Vostatková L., Adamcová M., Hroch M., Pokorná Z., Kovaříková P. Šimůnek T, Štěrba M. Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings? Toxicology. 2016; 372:52-63. (IF2015=3.817)

Hašková P., Jansová H., Bureš J., Macháček M., Jirkovská A., Franz K.J., Kovaříková P., Šimůnek T. Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. Toxicology. 2016; 371:17-28. (IF2015=3.817)

Snejdrova E., Drastik M ., Dittrich M., Kastner P., Nguyenova J. Mucoadhesive plasticized system of branched poly(lactic-co-glycolic acid) with aciclovir. Drug Development and Industrial Pharmacy. 2016; 42; 1653-9 (IF2015=2.429)

Tycova A., Vido M., Kovarikova P., Foret F. Interface-free capillary electrophoresis-mass spectrometry system with nanospray ionization-Analysis of dexrazoxane in blood plasma, Journal of Chromatography A. 2016; 1466: 173-179. (IF2015=3.926)

Hrušková K., Potůčková E., Hergeselová T., Liptáková L., Hašková P., Mingas P., Kovaříková P., Šimůnek T., Vávrová K. Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications, European Journal of Medicinal Chemistry. 2016; 120:97-110 (IF2015=3.902)

Jansová H., Bureš J., Macháček M., Hašková P., Jirkovská A., Roh J., Wang Q., Franz K.J., Kovaříková P., Šimůnek T. Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products, Toxicology. 2016; 350-352:15-24 (IF2015=3.817)

Macháček, M., Kollár, J., Miletin M., Kučera R., Kubat, P., Šimůnek T., Nováková V., Zimčík P. Anionic hexadeca-carboxylate tetrapyrazinoporphyrazine: synthesis and in vitro photodynamic studies of a water-soluble, non-aggregating photosensitizer, RSC Advances. 2016; 6(12): 10064-10077. (IF2015= 3.289)

Sestak V., Roh J., Klepalova L., Kovarikova P. A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor, Journal of Pharmaceutical and Biomedical Analysis. 2016; 124: 365-73 (IF2015=3.169)

Klivický M., Klimeš J., Kučera R. Solid-Phase Extraction of Ibuprofen from Pharmaceuticals via Ligand Exchange Using Zirconium Dioxide, Current Analytical Chemistry. 2016; 12(6): 523-528. (IF2015 = 1.132)

2015

Hofman, J., Kučera, R., Neumanova, Z., Klimeš, J., Ceckova, M., Staud, F. Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs), Xenobiotica. 2015; 46(5): 416-423. (IF2015= 1.723)

Kastner P., Burdová K., Pilařová P. HPLC method for stability evaluation of pharmaceutical preparations containing sodium picosulfate, Česká a slovenská farmacie. 2015; 64: 215.

Suchá L., Kolenič M., Kratochvíl J., Pour M., Nobilis M., Čermáková E., Řezáčová M., Tomšík P.  Novel derivatives of benfluron and dimefluron: synthesis and anticancer activity. Letters in Drug Design&Discovery. 2015; 12(10): 787-801. (IF2014= 0.770)

Šesták V., Stariat J., Cermanová J., Potůčková E., Chládek J., Roh J., Bureš J., Jansová H., Průša P., Stěrba M., Mičuda S., Šimůnek T., Kalinowski D. S., Richardson D.R., Kovaříková R. Novel and Potent Anti-Tumor and Anti-Metastatic Di-2-Pyridylketone Thiosemicarbazones Demonstrate Marked Differences in Pharmacology Between the First and Second Generation Lead Agents, Oncotarget. 2015; 6(40): 42411-42428 (IF2015= 5.008)

Potůčková E., Roh J., Macháček M., Sahni S., Stariat J., Šesták V., Jansová H., Hašková P., Jirkovská A., Vávrová K., Kovaříková P., Kalinowski D. S., Richardson D. R., Šimůnek T. In vitro characterization of the pharmacological properties of the anti-cancer chelator, Bp4eT, and ts phase I metabolites, PLoS ONE. 2015; 10(10): e0139929. doi:10.1371/journal.pone.0139929 (IF2015=3.007)

Cihalova, D., Ceckova, M., Kučera, R., Klimeš, J., Staud, F. Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro. Biochemical Pharmacology. 2015; 98(3): 465-472. (IF2015= 5.091)

Vachova, L., Machacek, M., Kučera, R., Demuth, J.; Cermak, P., Kopecky, K., Miletin, M., Jedlickova, A., Simunek, T., Novakova, V., Zimcik, P. Heteroatom-substituted tetra(3,4-pyrido)porphyrazines: a stride toward near- infrared-absorbing macrocycles. Organic & Biomolecular Chemistry. 2015; 13(20): 5608-5612.  (IF2015=3.559)

Macháček, M., Cidlina A., Nováková V., Švec J., Rudof E., Miletin M., Kučera R., Šimůnek T., Zimčík P. Far-Red-Absorbing Cationic Phthalocyanine Photosensitizers: Synthesis and Evaluation of the Photodynamic Anticancer Activity and the Mode of Cell Death Induction. Journal of Medicinal Chemistry. 2015; 58(4): 1736-1749. (IF2015= 5.589)

Bureš J., Jansová H., Stariat J., Filipský T., Mladěnka P., Šimůnek T., Kučera R., Klimeš J., Wang Q., Franz K.J., Kovaříková P. LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). Journal of Pharmaceutical and Biomedical Analysis. 2015; 105(1): 55-63. (IF2014= 2.979)

Servusova-Vanaskova, B., Jandourek, O., Paterova, P., Kordulakova, J., Plevakova, M., Kubicek, V., Kučera, R., Garaj, V., Naesens, L., Kunes, J., Dolezal, M., Zitko, J. Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation. Medchemcomm. 2015; 6(7): 1311-1317. (IF2015= 2.319)

2014

Potůčková E., Hrušková K., Bureš J., Kovaříková P., Špirková I.A., Pravdíková K., Kolbabová L., Hergeselová T., Hašková .P, Jansová H, Macháček M., Jirkovská A., Richardson V., Lane D.J., Kalinowski D.S., Richardson D.R., Vávrová K., Šimůnek T. Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties. PLoS One. 2014, 9(11): e112059.  (IF2014= 3.234)

Cermanova J., Kadova Z., Dolezelova E., Zagorova M., Safka V., Hroch M., Laho T., Holeckova M., Mokry J., Kovarikova P., Bures J., Sterba M., Micuda S. Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats. Shock. 2014, 42(4):372-79. (IF2014= 3.045)

Kučera R., Kovaříková P., Pasáková-Vrbatová .I, Slaninová J., Klimeš J. Zirconia-a stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography. Journal of Separation Science. 2014, 37(9-10):1089-93. (IF2014= 2.737)

Servusová-Vanasková, B., Paterová, P., Mandikova, J., Plevakova, M., Kubicek, V., Kučera, R., Kunes, J., Dolezal, M., Zitko, J. Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation. Bioorganic & Medicinal Chemistry Letters. 2014; 24(2): 450-453. (IF2014= 2.420)

Stariat J., Suprunová V., Roh J., Šesták V., Eisner T., Filipský T., Mladěnka P., Nobilis M., Šimůnek T., Klimeš J., Kalinowski D.S., Richardson D.R., Kovaříková P. Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats. Biomedical Chromatography. 2014; 28(5): 621-629.. (IF2014= 1.723)

Česlová L., Holčapek M., Nobilis M. Identification of combined conjugation of nabumetone phase I metabolites with glucuronic acid and glycine in minipig biotransformation using coupling high-performance liquid chromatography with electrospray ionization mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis. 2014; 88: 221-224. (IF2014=2.979)

2013

Hofman J., Kucera R., Cihalova D., Klimes J., Ceckova M., Staud F. Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1), Plos one. 2013; 8(10). (IF2013=3.534)

Škarydová L., Nobilis M., Wsól V. Role of carbonyl reducing enzymes in the phase I biotransformation of the NSAID nabumetone in vitro, Xenobiotica. 2013; 43(4):346-354. (IF2013=2.101)

Zitko, J., Servusová, B., Paterová, P., Mandikova, J., Kubicek, V., Kučera, R., Hrabcova, V., Kunes, J., Soukup, O., Dolezal, M., Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides, Molecules. 2013; 18(12): 14807-14825. (IF2013=2.095)

Smetanová L., Štětinová V., Kholová D., Kuneš M., Nobilis M., Svoboda Z., Květina J. Transintestinal transport mechanisms of 5-aminosalicylic acid (in situ rat intestine perfusion, Caco-2 cells) and Biopharmaceutics Classification System, General Physiology and Biophysics. 2013; 32(3):361-369. (IF2013=0.875)

Nobilis M., Mikušek J., Szotáková B., Jirásko R., Holčapek M., Chamseddin C., Jira Th., Kučera R., Kuneš J., Pour M. Analytical power of LLE-HPLC-PDA-MS/MS in drug metabolism studies: Identification of new nabumetobe metabolites, Journal of Pharmaceutical and Biomedical Analysis. 2013; 80:164-172. (IF2013=2.829)

Pilařová P., Kastner P., Nejedlý T., Klimeš J. Development and validation of rapid UHPLC method for determination of aciclovir, its impurities and preservatives in topical cream, Analytical Methods. 2013; 5(10):2610-14. (IF2013= 1.938)

Opletalová V., Kastner P., Kučerová-Chlupáčová M., Palát K. Study of hydrophobic properties of biologically active open analogues of flavonoids, Journal of Molecular Graphics & Modelling. 2013; 39:61–64. (IF2013= 2.022)

Cahlikova L., Locarek M., Benesova N., Kucera R., Chlebek J., Novak Z., Opletal L. Isolation and Cholinesterase Inhibitory Activity of Narcissus Extracts and Amaryllidaceae Alkaloid, Natural Product Communications. 2013; 8(6):781-785. (IF2013= 0.924)

Pilařová P. Kastner P., Klimeš J. Determination of Amphetamine and Methamphetamine And Their 4-Hydroxy Derivatives by HPLC with Fluorescence Detection, Chemické Listy. 2013; 107(1): 58-61. (IF2013 = 0,196)

Stariat J., Kovaříková P., Kučera R., Klimeš J., Kalinowski D.S, Richardson D.R, Ketola R.A. Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry, Analytical and Bioanalytical Chemistry. 2013; 405(5):1651-61. (IF2013= 3.578)

Kovaříková P., Pasaková-Vrbatová I., Vávrová A., Stariat J., Klimeš J., Simunek T. Development of LC–MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium, Journal of Pharmaceutical and Biomedical Analysis .2013; 76(1): 243-51. (IF2012= 2.829)

Štěrba M., Popelová O., Vávrová A., Jirkovský E., Kovaříková P., Geršl V., Šimůnek T. Oxidative stress, redox signaling and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection, Antioxidants & Redox Signaling. 2013;18(8): 899-929. (IF2013: 7.667)

2012

Kalafut P., Kučera R., Klimeš J. The Retention Behavior of Acidic, Basic and Neutral Pharmaceuticals on the Deactivated Polybutadiene Zirconia Phase, Current Analytical Chemistry. 2012; 8(4): 574-582. (IF2012: 1.558) 

Kalafut P., Kučera R., Klimeš J. The influence of a carbon layer deposited on a zirconia surface on the retention of polar analytes in an organic rich mobile phase , Journal of Chromatography A. 2012; 1232 : 242-247. (IF2012: 4.612) 

Cahlíková L., Kučera R., Hošťálková, A.,Klimeš J., Opletal L. Identification of Pavinane Alkaloids in the Genera Argemone and Eschscholzia by GC-MS Natural Product Communications. 2012; 7(10): 1279-1281. (IF2012: 0.956)

Cahlíková L., Benešová N., Macáková K., Kučera R., Hrstka V., Klimeš J., Jahodář L., Opletal L. Alkaloids from some amaryllidaceae species and their cholinesterase activity, Natural Product Communications. 2012; 7(5): 571-574. (IF2012: 0.956) 

Novakova V., Kobak R.Z.U., Kučera R., Kopecky K., Miletin M., Krepsová V., Ivincová J., Zimcik P. The effect of the number of carbohydrate moieties on the azaphthalocyanine properties, Dalton Transactions. 2012;  41: 10596-10604. (IF2012: 3.806)

Macková E., Hrušková K., Bendová P., Vávrová A., Jansová H., Hašková P., Kovaříková P., Vávrová K., Šimůnek T. Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action, Chemico-Biological Interactions. 2012; 197: 69-79. (IF2012: 2.967)

Stariat J., Šesták V., Vávrová K., Nobilis M., Kollárová Z., Klimeš J., Kalinowski D.S., Richardson D.R., Kovaříková P. LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT, Analytical and Bioanalytical Chemistry. 2012; 403(1): 309-321. (IF2012= 3.659)

Hroch M., Havlinova Z., Nobilis M., et al. HPLC determination of arginases inhibitor N-(omega)-hydroxy-nor-L-arginine using core-shell particle column and LC-MS/MS identification of principal metabolite in rat plasma, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences.2012; (880): 90-99. (IF2012: 2.487)

2011 

Kučera R., Kovaříková P., Klivický M., Klimeš J. The retention behaviour of polar compounds on zirconia based stationary phases under hydrophilic interaction liquid chromatography conditions, Journal of Chromatography A. 2011; 1218(39): 6981-6986. (IF2011: 4.531)

Kopecky K., Novakova V., Miletin M., Kučera R., Zimcik P. Synthesis of new azaphthalocyanine dark quencher and evaluation of its quenching efficiency with different fluorophores, Tetrahedron. 2011; 67(33): 5956-5963. (IF2011: 3.025)

Zítko J., Doležal M., Svobodová M., Vejsová M., Kuneš J., Kučera R., Jílek P. Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides, Bioorganic & Medicinal Chemisty. 2011; 19(4): 1471-1476. (IF2011: 2.921)

Vávrová K., Kovaříková P., Školová B., Líbalová M., Roh J., Čáp R., Holý A., Hrabálek A. Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP, Pharmaceutical Research. 2011; 28(12): 3105-3115.  (IF2011: 4.093)

Hašková P., Koubková L., Vávrová A., Macková E., Hrušková K., Kovaříková P., Vávrová K., Šimůnek T. Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity, Toxicology. 2011; 289(2-3): 122-131. (IF2011: 3.681)

Pasáková I., Gladziszová M., Charvátová J., Stariat J., Klimeš J., Kovaříková P. Use of different stationary phases for separation of isoniazid, its metabolites and vitamin B6 forms, Journal of Separation Science. 2011; 34(12): 1357-1365. (IF2011: 2.733)

Hrušková K., Kovaříková P., Bendová P., Hašková P., Macková E., Stariat J., Vávrová A., Vávrová K., Šimůnek T. Synthesis and initial in vitro evaluations of novel antioxidant aroylhydrazone iron chelators with increased stability against plasma hydrolysis, Chemical Research in Toxicology. 2011; 24(3): 290-302. (IF2011: 3.779)

Hašková P., Kovaříková P., Koubková L., Vávrová A., Macková E., Šimůnek T. Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autooxidation and cardiotoxicity, Free Radical Biology and Medicine. 2011; 50(4): 537-549. (IF2011: 5.423)

Kovaříková P., Stariat J., Klimeš J., Hrušková K., Vávrová K. Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case, Journal of Chromatography A. 2011; 1218(3): 416-426. (IF2011: 4.531)

Nobilis M., Vybiralova Z., Szotakova B., et al. High-performance liquid chromatographic determination of tiapride and its phase I metabolite in blood plasma using tandem UV photodiode-array and fluorescence detection, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences.2011; 879(32): 3845-3852.(IF2011: 2.888)

Jirasko R., Holcapek M., Nobilis M. Identification of phase I and phase II metabolites of benfluron and dimefluron in rat urine using high-performance liquid chromatography/tandem mass spectrometry, Rapid Communications in Mass Spectrometry. 2011; 25(15): 2153-2162. (IF2011: 2.790)

2010

Kopecky K., Novakova V., Miletin M., Kučera R., Zimcik P. Solid-Phase Synthesis of Azaphthalocyanine-Oligonucleotide Conjugates and Their Evaluation As New Dark Quenchers of Fluorescence, Bioconjugate Chemistry. 2010; 21(10): 1872-1879. (IF2010: 5.002)

Bendová P., Macková E., Hašková P., Vávrová A., Jirkovský E., Šterba M., Popelová O., Kalinowski D.S, Kovaříková P., Vávrová K., Richardson D.R, Šimůnek T. Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury, Chemical Research in Toxicology. 2010; 23(6): 1105-1114. (IF2010: 4.140)

Stariat J., Kovaříková P., Klimeš J., Kalinowski D.S., Richardson D.R. Development of an LC-MS/MS method for analysis of interconvertible Z/E Isomers of novel anti-cancer agent, Bp4eT, Analytical and Bioanalytical Chemistry. 2010; 397(1): 161-171. (IF2010: 3.841)

Mokry M., Klimes J., Pechova J. HPLC analysis of syrup containing nimesulide and its hydrolytic degradation product, Chemical Papers. 2010; (64): 405-408. (IF2010: 0.754)

Senel P., Tichotova L., Votruba I., Nobilis. M., et al. Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivativesBioorganic & Medicinal Chemistry. 2010; 18(5): 1988-2000. (IF2010: 2.978)

2009

Kalafut P., Kučera R., Klimeš J., Sochor J. An innovative approach to the analysis of 3-[4-(2-methylpropyl)phenyl]propanoic acid as an impurity of ibuprofen on a carbon-coated zirconia stationary phase, Journal of Pharmaceutical and Biomedical Analysis. 2009; 49(5): 1150- 1156. (IF2009: 2.453)

Žižkovský V., Kučera R., Klimeš J., Holásková P. Dohnal J. RP-ZrO2 stationary phase as an alternative to separate of doxazosin impurities, Chromatographia. 2009; 70(1-2): 185-189. (IF2009: 1.098)

Pasáková I., Kovaříková P., Kučera R., Klimeš J., Sochor J., Hrábalek A. Development and validation of an LC-ESI-MS ion-trap method for analysis of impurities in Transkarbam 12, a novel transdermal accelerant, Chromatographia. 2009; 96(9-10): 977 – 983. (IF2009: 1.098)

Novotný J., Kovaříková P., Novotný M., Janušová B., Hrabálek A., Vávrová K. Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: Effects of linking chain length, chirality and polyfluorination, Pharmaceutical Research. 2009; 26(4): 811 – 821. (IF2009: 3.933)

Stariat J., Kovaříková P., Klimeš J., Lovejoy D.B., Kalinowski D.S., Richardson D.R. HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents, Journal of Chromatography . 2009; 877(3): 316 – 322. (IF2009: 2.777)

Krizova V., Nobilis M., Pruskova L., et al. Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries), Journal Of Veterinary Pharmacology And Therapeutics. 2009; 32(6): 606-612. (IF2009: 1.408)

2008 

Žižkovský V., Kučera R., Klimeš J., Dohnal J. Titania-based stationary phase in separation of ondansetron and its related compounds, Journal of Chromatography A. 2008; 1189(1-2): 83-91. (IF2008: 3.756)

Kovaříková P., Vávrová K., Tomalová K., Schöngut M., Hrušková K., Hašková P. Klimeš J. HPLC-DAD and MS/MS analysis of novel drug candidates from the group of aromatic hydrazones revealing the presence of geometric isomers, Journal of Pharmaceutical and Biomedical Analysis. 2008; 48(2): 295 - 302. (IF2008: 2.629)

Mrkvičková Z., Kovaříková P., Balíková S., Klimeš J. Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations, Journal of Pharmaceutical and Biomedical Analysi. 2008; 48(2): 310 - 314. (IF2008: 2.629)

Kovaříková P., Mrkvičková Z., Klimeš J. Investigation of the stability of aromatic hydrazones in plasma and related biological material, Journal of Pharmaceutical and Biomedical Analysis. 2008; 47(2): 360 – 370. (IF2008: 2.629)

Nobilis M., Vybiralova Z., Krizova V., et al. Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection Application to pharmacokinetic studies in sheep, Journal of Chromatography B-Analytical Technologies in The Biomedical and Life Sciences. 2008; 876(1): 89-96. (IF2008: 2.500)

Kubicek V., Soukupova M., Nobilis M., et al. LC with Fluorimetric Detection for Sensitive Analysis of Reduced Flubendazole in Biological Samples, Chromatographia. 2008; 68( 9-10): 865-867. (IF2008: 1.312)

Holcapek M., Kolarova L., Nobilis M. High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites, Analytical and Bioanalytical Chemistry. 2008; 391(1): 59-78.. (IF2008: 3.328)

Cvilink V., Kubicek V., Nobilis M., et al. Biotransfonnation of flubendazole and selected model xenobiotics in Haemonchus contortus, Veterinary Parasitology. 2008; 151(2-4): 242-248. (IF2008: 2.039)

Pilarova P., Kastner P., Klimes J. Isolation and Identification of Amphetamines in Urine by Thin-Layer Chromatography,  Jpc-Journal of Planar Chromatography-Modern Tlc. 2008; 21(6): 465-468. (IF2008: 0.982)

2007 

Zerzaňová A., Žižkovský V., Kučera, R., Klimeš J., Jesenský I., Dohnal J., Barrón D. Using of HPLC coupled with coulometric detector for the determination of biotin in pharmaceuticals,  Journal of Pharmaceutical and Biomedical Analysis. 2007; 45(5): 730-735. (IF2007: 2.761)

Žižkovský V., Kučera R., Klimeš J., Dohnal J. Potential employment of non-silica-based stationary phases in pharmaceutical analysis, Journal of Pharmaceutical and Biomedical Analysis. 2007; 44(5): 1048-1055. (IF2007: 2.761)

Malakova J., Nobilis M., Svoboda Z., Lisa M., Holcapek M., Kvetina J., Klimes J., Palicka V. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples, Journal Of Chromatography B-Analytical Technologies In The Biomedical And Life Sciences. 2007; 853(1-2): 265-274. (IF2007: 2.935)

Nobilis M., Pour M., Senel P., et al. Metabolic profiling of a potential antifungal drug, 3-(4-bromophenyl)-5-acetoxymethyl-2,5-dihydrofuran-2-one, in mouse urine using high-performance liquid chromatography with UV photodiode-array and mass spectrometric detection, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2007; 853(1-2): 10-19. (IF2007: 2.935)

Nobilis M., Jira T., Lisa M., et al. Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection, Journal of Chromatography A .2007; 1149 (1): 112-120. (IF2007: 3.641)

Slanar O., Nobilis M., Kvetina J., et al. Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T, European Journal of Clinical Pharmacology. 2007; 63(4): 419-421. (IF2007: 2.177)

Slanar O., Nobilis M., Kvetina J., et al. Miotic action of tramadol is determined by CYP2D6 genotype, Physiological Research. 2007; 56(1): 129-136. (IF2007: 1.505)

Mrkvičková Z., Kovaříková P., Klimeš J., Kalinowski D., Richardson D.R.  Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity, Journal of Pharmaceutical and Biomedical Analysis. 2007; 43(4):  1343 - 1351. (IF2007: 2.761)

2006

Garcés A., Zerzaňová A., Kučera, R., Barrón, D., Barbosa, J. Determination of a series of quinolones in pig plasma using solid-phase extraction and liquid chromatography coupled with mass spectrometric detection. Application to pharmacokinetic studies,  Journal of Chromatography A. 2006; 1137(1): 22-29. (IF2006: 3.554)

Mrkvičková Z., Kovaříková P., Klimeš J., Doležal M. Determination of the lipophilicity of potential antituberculotic compounds by RP-TLC, Journal of Planar Chromatography. 2006; 19(112): 422 - 426. (IF2006: 1.153)

Kovaříková P., Klimeš J., Štěrba M., Popelová O., Geršl V., Poňk, P. HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study, Journal of Chromatography B. 2006; 838(2): 107 - 112. (IF2006: 2.647)

Kovaříková P., Mokrý M., Klimeš J., Vávrová K. HPLC study on stability of pyridoxal isonicotinoyl hydrazone, Journal of Pharmaceutical and Biomedical Analysis. 2006; 40(1): 105 - 112. (IF2006: 2.032)

Pasakova I., Klimes J., Sochor J., Hrabalek A. Optimization of HPLC chromatographic conditions for determination of Transkarbam 12 and its degradation products, Journal of Pharmaceutical and Biomedical Analysis.2006; 42(1): 136-142. (IF2006: 2.032)

Pasakova I., Sochor J., Klimes J.,Hrabalek A. Preliminary pharmaceutico-analytical evaluation of Transkarbam 12 using liquid chromatography, Journal of Separation Science. 2006; 29(11): 1595-1599. (IF2006: 2.535)

Kresta J., Kastner P., Klimes J., Klimesova J. Reversed-phase thin-layer chromatographic determination of the lipophilicity of potential antituberculotic compounds, Jpc-Journal of Planar Chromatography-Modern Tlc. 2006; 18(106): 450-454. (IF2006: 1.153)

Zerzanova A., Cisar P., Klimes J. Comparison of different stationary phases for bioanalytical studies of biologically active compounds, Journal of Separation Science.2006; (29): 2126–2135. (IF2006: 2.535)

Nobilis M., Vybiralova Z., Sladkova K., et al. High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma, Journal of Chromatography A.2006; 1119 (1-2): 299-308. (IF2006: 3.554)

2005

R. Kučera, V. Žižkovský, J. Sochor, J. Klimeš, J. Dohnal. Utilization of zirconia stationary phase as a tool in drug control, Journal of Separation Science. 2005; 28: 1307-1314. (IF2005: 1.829)

R. Kučera, J. Sochor, J. Klimeš, J. Dohnal. Use of the zirconia-based stationary phase for separation of ibuprofen and its impurities, Journal of Pharmaceutical and Biomedical Analysis. 2005; 38: 609-618. (IF2005: 1.889)

Kučera R., Nobilis M., Skálová L., Szotáková B., Císař P., Jira Th., Klimeš J., Wsól V. Use of chiral reversed-phase liquid chromatography for the evaluation of stereoselectivity in the karbonyl reduction of potential benzo(c)fluorene antineoplastics benfluron in various species, Journal of Pharmaceutical and Biomedical Analysis. 2005; 37: 1049-1057. (IF2005: 1.889)

Kovaříková P., Klimeš J., Štěrba M. Popelová O., Mokrý M., Geršl V., Poňka P. Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study, Journal of Separation Science. 2005; 28(12): 1300 - 1306. (IF2005: 1.829)

Hanysova L., Vaclavkova M., Dohnal J., Klimes J.Stability of ramipril in the solvents of different pH, Journal of Pharmaceutical and Biomedical Analysis. 2005; (37): 1179–1183. (IF2005: 1.889)
Cisar P., Nobilis M., Vybiralova Z., et al. Disposition study of a new potential antineoplastic agent dimefluron in rats using high-performance liquid chromatography with ultraviolet and mass spectrometric detection, Journal of Pharmaceutical and Biomedical Analysis.2005; 37(5): 1059-107. (IF2005: 1.889)

Hanysova L., Mokry M., Kastner  P., et al. HPLC evaluation of diclofenac in the various forms of therapeutic preparations, Chemical Papers. 2005; 59(2): 103-108. (IF2005: 0.409)

Hanysova L., Kastner P., Klimes J. Degradation products and impurities of paracetamol from viewpoint of analytical detection, Chemicke Listy. 2005; 99(9): 647-652. (IF2005: 0.445)

Vybiralova Z., Nobilis M., Zoulova J., et al. High-performance liquid chromatographic determination of ciprofloxacin in plasma samples, Journal of Pharmaceutical and Biomedical Analysis. 2005; 37(5): 851-858. (IF2005: 1.889)

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