Publications

2017

  • SEMELKOVÁ, L.; JANOŠCOVÁ, P.; FERNANDES, C.; BOUZ, G.; JANĎOUREK, O.; KONEČNÁ, K.; PATEROVÁ, P.; NAVRÁTILOVÁ, L.; KUNEŠ, J.; DOLEŽAL, M.; ZITKO, J. Design, Synthesis, Antimycobacterial Evaluation, and In Silico Studies of 3-(Phenylcarbamoyl)-pyrazine-2-carboxylic Acids. Molecules 2017, vol. 22, no. 9, Article No. 1491.  [ISSN 1420-3049] IF2016 = 2.861, doi: 10.3390/molecules22091491
  • JOSEPH, T.; VARGHESE, H. T.; PANICKER, C. Y.; VISWANATHAN, K.; DOLEŽAL, M.; ALSENOY, C. V. Spectroscopic (FT-IR, FT-Raman), first order hyperpolarizability, NBO analysis, HOMO and LUMO analysis of N-[(4-(trifluoromethyl)phenyl]pyrazine-2-carboxamide by density functional methods. Arab. J. Chem., 2017, vol. 10, no. S2, p. S2281–S2294. [ISSN 1878-5352], IF2016 = 4.553, doi: 10.1016/j.arabjc.2013.08.004
  • SEMELKOVÁ, L.; JANĎOUREK, O.; KONEČNÁ, K.; PATEROVÁ, P.; NAVRÁTILOVÁ, L.; TREJTNAR, F.; KUBÍČEK, V.; KUNEŠ, J.; DOLEŽAL, M.; ZITKO, J. 3-Substituted N-Benzylpyrazine-2-carboxamide Derivatives: Synthesis, Antimycobacterial and Antibacterial Evaluation. Molecules, 2017, vol. 22, no. 3, Article No. 495. [ISSN 1420-3049] IF2015 = 2.465, doi:10.3390/molecules22030495
  • JANDOUREK, O.; TAUCHMAN, M.; PATEROVA, P.; KONECNA, K.; NAVRATILOVA, L.; KUBICEK, V.; HOLAS, O.; ZITKO, J.; DOLEZAL, M. Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation. Molecules, 2017, vol. 22, no. 2, Article No. 223. [ISSN 1420-3049] IF2015 = 2.465, doi: 10.3390/molecules22020223
  • P.K. RANJITH, ; EBTEHAL S. AL-ABDULLAH, FATMAH A.M. AL-OMARY, ALI A. EL-EMAM, P.L. ANTO, MARY Y. SHEENA, STEVAN ARMAKOVIĆ, SANJA J. ARMAKOVIĆ, JAN ZITKO, MARTIN DOLEZAL, C. VAN ALSENOY. FT-IR and FT-Raman characterization and investigation of reactive properties of N-(3-iodo-4-methylphenyl)pyrazine-2-carboxamide by molecular dynamics simulations and DFT calculations. J. Mol. Struct., 2017, vol. 1136, p. 14–24. [ISSN 0022-2860] IF2015 = 1.780, doi: 10.1016/j.molstruc.2017.01.079
  • BEEGUM, S.; MARY, Y. S.; VARGHESE, H. T.; PANICKER, C. Y.; ARMAKOVIĆ, S.; ARMAKOVIĆ, S. J.; ZITKO, J.; DOLEŽAL, M.; VAN ALSENOY, C. Vibrational spectroscopic analysis of cyanopyrazine-2-carboxamide derivatives and investigation of their reactive properties by DFT calculations and molecular dynamics simulations. J. Mol. Struct., 2017, vol. 1131, p. 1–15. [ISSN 0022-2860] IF2015 = 1.780, doi: 10.1016/j.molstruc.2016.11.044

2016

  • ZITKO, J.; DOLEŽAL, M. Enoyl acyl carrier protein reductase inhibitors: an updated patent review (2011 – 2015). Exp. Opin. Ther. Pat., 2016, vol. 26, p. 1079-1094.  [ISSN 1354-3776 (Print)], [ISSN 1744-7674 (Online)]. IF2015: 4.626. doi: 10.1080/13543776.2016.1211112.
  • OPLETALOVA, V.; DOLEZEL, J.; KUNES, J.; BUCHTA, V.; VEJSOVA, M.; KUCEROVA-CHLUPACOVA, M.: Synthesis and Antifungal Screening of 2-{[1-(5-Alkyl/arylalkylpyrazin-2-yl)ethylidene]hydrazono}-1,3-thiazolidin-4-ones. Molecules 2016, vol. 21, no. 11, p. 1592. [ISSN 1420-3049] IF2015 = 2.465, doi:10.3390/molecules21111592
  • KUCEROVA-CHLUPACOVA, M.; VYSKOVSKA-TYLLOVA, V.; RICHTEROVA-FINKOVA, L.; KUNES, J.; BUCHTA, V.; VEJSOVA, M.; PATEROVA, P.; SEMELKOVA, L.; JANDOUREK, O.; OPLETALOVA, V.: Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs. Molecules 2016, vol. 21, no. 11, p. 1421. [ISSN 1420-3049] IF2015 = 2.465, doi: 10.3390/molecules21111421
  • DOLEŽAL, M.; ZITKO, J.; JANĎOUREK, O.; SERVUSOVÁ-VAŇÁSKOVÁ B. Substituted 2-(2-phenylhydrazinyl)pyrazine, process for its preparation, its use and a pharmaceutical composition containing the same. WO 2016/095877 A1 (PCT/CZ2015/000127).
  • DOLEŽAL, M.; ZITKO, J.; JANĎOUREK, O.; SERVUSOVÁ-VAŇÁSKOVÁ B. Substituovaný 2-(2-fenylhydrazinyl)pyrazin, způsob jeho přípravy, jeho použití a farmaceutický přípravek ho obsahující. PV 2014-925.
  • SEBASTIAN, S. H. R.; AL-ALSHAIKH, M. A.; EL-EMAM, A. A.; PANICKER, C. Y.; ZITKO, J.; DOLEZAL, M.; VAN ALSENOY, C. Spectroscopic, quantum chemical studies, Fukui functions, in vitro antiviral activity and molecular docking of 5-chloro-N-(3-nitrophenyl)pyrazine-2-carboxamide. J. Mol. Struct.,  2016, vol. 1119, p. 188–199. [ISSN 0022-2860] IF2015 = 1.780, doi: 10.1016/j.molstruc.2016.04.088
  • HROCH, L.; BENEK, O.; GUEST, P.; AITKEN, L.; SOUKUP, O.; JANOČKOVÁ, J.; MUSIL, K.; DOHNAL, V.; DOLEŽAL, R.; KUČA, K.; SMITH, T. K.; GUNN-MOORE, F.; MUSÍLEK, K. Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment. Bioorg. Med. Chem. Lett., 2016, vol. 26, p. 3675–3678. [ISSN 0960-894X]. IF2015 = 2.486, doi: 10.1016/j.bmcl.2016.05.087
  • TŮMOVÁ, L.; TŮMA, J.; DOLEŽAL, M.; DUČAIOVÁ, Z.; KUBEŠ J. New Synthetic Pyrazinecarboxamide Derivatives as Potential Elicitors in Production of Secondary Metabolite in In vitro Cultures. Pharmacogn. Mag., 2016, vol. 12, no. 45, Suppl. 1, p. 57–62. [ISSN 0976-4062], IF2014 = 1.256, doi: 10.4103/0973-1296.176117

  • ZITKO, J.; SERVUSOVA-VANASKOVA, B.; PATEROVA, P.; NAVRATILOVA, L.; TREJTNAR, F.; KUNES, J.; DOLEZAL, M. Design, Synthesis and Antimycobacterial Evaluation of Some New N-Phenylpyrazine-2-Carboxamides. Chem. Pap., 2016, vol. 70, no. 5, p. 649–657. [ISSN (Online) 1336-9075], [ISSN (Print) 0366-6352], IF2014 = 1.468. doi: 10.1515/chempap-2015-0246

2015

  • ZITKO, J.; DOLEŽAL, M. Indole-carboxamide derivatives: a patent evaluation of WO2015036412A1. Exp. Opin. Ther. Pat., 2015, vol. 25, p. 1487–1494. [ISSN 1354-3776]. IF2014 = 4.297. doi: 10.1517/13543776.2015.1101066
  • HIRSOVA, P.; DOLEZEL, J.; KUCEROVA-CHLUPACOVA, M.; KUNES, J.; PILAROVA, V.; NOVAKOVA, L.; OPLETALOVA, V. (Z)-3-Amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one. Molbank, 2015, vol. 2015, M872. [ISSN 1422-8599]. doi: 10.3390/M872
  • MAREK, J.; MALIŇÁK, D.; DOLEŽAL, R.; SOUKUP, O.; PASDIOROVÁ, M.; DOLEŽAL, M.; KUČA, K. Synthesis and disinfection effect of the pyridine-4-aldoxime based salts. Molecules, 2015, vol. 20, no. 3, p. 3681-3696. [ISSN 1420-3049], IF2014 = 2.095; doi: 10.3390/molecules20033681
  • RESMI, K. S.; PANICKER, C. Y.; ZITKO, J.; DOLEZAL, M.; WAR, J.A.; SRIVASTAVA, S. K.; VAN ALSENOY, C. FT-IR, FT-Raman, NBO, HOMO-LUMO analysis and molecular docking study of 5-chloro-N-(2-fluorophenyl)pyrazine-2-carboxamide. Sci. Lett., 2015, vol. 4, p. 216. [ISSN 2454–7239].
  • SERVUSOVA-VANASKOVA, B.; JANDOUREK, O.; PATEROVA, P.; KORDULAKOVA, J.; PLEVAKOVA, M.; KUBICEK, V.; KUCERA, R.; GARAJ, V.; NAESENS, L.; KUNES, J.; DOLEZAL, M.; ZITKO, J. Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: Synthesis and antimycobacterial evaluation. MedChemComm, 2015, vol. 6, p. 13111317. [ISSN 2040-2503], IF2013 = 2.626. doi: 10.1039/C5MD00178A
  • SEMELKOVA, L.; KONECNA, K.; PATEROVA, P.; KUBICEK, V.; KUNES, J.; NOVAKOVA, L.; MAREK, J.; NAESENS, L.; PESKO, M.; KRALOVA, K.; DOLEZAL, M.; ZITKO, J. Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides. Molecules, 2015, vol. 20, p. 8687–8711. [ISSN 1420-3049], IF2013 = 2.095. doi: 10.3390/molecules20058687
  • ZITKO, J.; FRANCO, F.; PATEROVÁ, P. Synthesis and anti-infective evaluation of 5-amino-N-phenylpyrazine-2-carboxamides. Čes. Slov. Farm., 2015, vol. 64, p. 19–24. [ISSN 1210-7816].
  • JANĎOUREK, O.; KUNEŠ, J.; DOLEŽAL, M.; Microwave-Assisted Synthesis of Pyrazinamide Derivatives: the Coupling Reaction of 3-Chloropyrazine-2-Carboxamide and Ring-Substituted Anilines. Curr. Org. Synthesis, 2015, vol. 12, no. 2, p. 189–196. [ISSN 1875-6271], IF2014 = 2.117. doi: 10.2174/1570179411999141106101501
  • HOLAS, O.; SLOVÁK, F.; DOLEŽAL, M. Computational approach to search for novel antituberculotics. Čes. Slov. Farm., 2015, vol. 64, no. 1-2, p. 32–33. [ISSN 1803-6597].
  • SERVUSOVÁ-VAŇÁSKOVÁ, B.; PATEROVÁ P.; GARAJ, V.; MANDÍKOVA, J.; KUNEŠ J.; NAESENS, L.; JÍLEK, P.; DOLEŽAL, M.; ZITKO, J. Synthesis and antimicrobial evaluation of 6-alkylamino-N-phenyl-pyrazine-2-carboxamides. Chem. Biol. Drug Des., 2015, vol. 86, p. 674–681. [ISSN 1747-0285].  IF2013 = 2.507. doi: 10.1111/cbdd.12536
  • KUCEROVA-CHLUPACOVA, M.; KUNES, J.; BUCHTA, V.; VEJSOVA, M.; OPLETALOVA, V. Novel Pyrazine Analogs of Chalcones: Synthesis and Evaluation of Their Antifungal and Antimycobacterial Activity. Molecules, 2015, vol. 20, p. 1104–1117. [ISSN 1420-3049], IF2013 = 2.095. doi: 10.3390/molecules20011104.
  • HROCH, L.; AITKEN, L.; BENEK, O.; DOLEŽAL, M.; KUČA, K.; GUNN-MOORE, F.; MUSÍLEK, K. Benzothiazoles - Scaffold of Interest for CNS Targeted Drugs. Curr. Med. Chem., 2015, vol. 22, in press. [0929-8673], IF2013 = 3.715. doi: 10.2174/0929867322666141212120631
  • ZITKO, J.; SERVUSOVÁ, B.; JANOUTOVÁ, A.; PATEROVÁ, P.; MANDÍKOVÁ, J.; GARAJ, V.; VEJSOVÁ, M.; MAREK, J.; DOLEŽAL, M. Synthesis and antimycobacterial evaluation of 5-alkylamino-N-phenylpyrazine-2-carboxamides. Bioorg. Med. Chem., 2015, vol. 23, p. 174–183. [ISSN 0968-0896], IF2013 = 2.951. doi: 10.1016/j.bmc.2014.11.014
  • BHAGYASREE, J. B.; VARGHESE, H. T.; PANICKER, C. Y.; VAN ALSENOY, C.; AL-SAADI, A. A.; DOLEZAL, M.; SAMUEL, J. Spectroscopic (FT-IR, FT-Raman), first order hyperpolarizability, NBO analysis, HOMO and LUMO analysis of 5-tert-Butyl-6-chloro-N-[(4-(trifluoromethyl)phenyl]pyrazine-2-carboxamide. Spectrochim. Acta Part A: Mol. Biomol. Spectr., 2015, vol. 137, p. 193–206. [ISSN 1386-1425]. doi: 10.1016/j.saa, IF2013 = 2.129
  • DOLEŽAL, M.; ZITKO, J. Pyrazine Derivatives: a patent review (June 2012-present). Exp. Opin. Ther. Pat., 2015, vol. 25, p. 33–47. [ISSN 1354-3776]. IF2013 = 3.441. doi: 10.1517/13543776.2014.982533
  • HOLAS, O.; ONDREJČEK, P.; DOLEŽAL, M. Recent progress in discovery of novel Mycobacterium tuberculosis enoyl-ACP reductase inhibitors. J. Enzym. Inhib. Med. Chem., 2015, vol. 30, p. 629-648. [ISSN 1475-6366] doi: 10.3109/14756366.2014.959512, IF2013 = 2.383

2014

  • OPLETALOVÁ, V.; DOLEŽEL, J.;  BUCHTA, V.; VEJSOVÁ, P. PATEROVÁ. Antifungal effects of (5Z)-5-arylmethylidenerhodanines with special view to the members of Mucorales. Folia Pharm. Univ. Carol. 2014, vol. 42, p. 7–13. [ISSN 1210-9495]
  • NEPOVIMOVA, E.; ULIASSI, E.; KORABECNY, J.; PENA-ALTAMIRA, L. E.; SAMEZ, S.; PESARESI, A.; GARCIA, G. E.; BARTOLINI, M.; ANDRISANO, V.; BERGAMINI, C.; FATO, R.; LAMBA, D.; ROBERTI, M.; KUCA, K.; MONTI, B.; BOLOGNESI, M. L. Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects. J. Med. Chem. 2014, vol. 57, p. 8576–8589. [ISSN 0022-2623]; doi:10.1021/jm5010804; IF2013 = 5.480
  • MALINAK, D.; DOLEZAL, R.; MAREK, J.; SALAJKOVA, S.; SOUKUP, O.; VEJSOVA, M.; KORABECNY, J.; HONEGR, J.; PENHAKER, M.; MUSILEK, K.; KUCA, K., 6-Hydroxyquinolinium salts differing in the length of alkyl side-chain: Synthesis and antimicrobial activity. Bioorg. Med. Chem. Lett., 2014, vol. 24, p. 5238––5241. [ISSN 0960-894X] IF2012 = 2.338, doi: 10.1016/j.bmcl.2014.09.060
  • HAMULAKOVÁ, S.; IMRICH, J.; JANOVEC, L.; KRISTIAN, P.; DANIHEL, I.; HOLAS, O.; POHANKA, M.; BÖHM, S.; KOZURKOVÁ, M.; KUČA K. Tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers. Int. J. Biol. Macromol., 2014, vol. 7, p. 435–439. IF2013 = 2.60. doi: 10.1016/j.ijbiomac.2014.06.064
  • JANĎOUREK, O.; DOLEŽAL, M.; KUNEŠ, J.; KUBÍČEK, V.; PATEROVÁ, P.; PEŠKO, M.; BUCHTA, V.; KRÁĽOVÁ, K.; ZITKO, J. New potentially active pyrazinamide derivatives synthesized under microwave conditions. Molecules, 2014, vol. 19, p. 9318–9338.  [ISSN 1420-3049], IF2013 = 2.095. doi: 10.3390/molecules19079318
  • KORABECNY, J.; DOLEZAL, R.; CABELOVA, P.; HOROVA, A.; HRUBA, E.; RICNY, J.; SEDLACEK, L.; NEPOVIMOVA, E.; SPILOVSKA, K.; ANDRS, M.; MUSILEK, K.; OPLETALOVA, V.; SEPSOVA, V.; RIPOVA, D.; KUCA, K. 7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies. Eur. J. Med. Chem., 2014, vol. 82, p. 426–438.  [ISSN 0223-5234], IF2012 = 3.849.  DOI: 10.1016/j.ejmech.2014.05.066
  • KORABECNY, J.; SOUKUP, O.; DOLEZAL, R.; SPILOVSKA, K.; NEPOVIMOVA, E.; ANDRS, M.; NGUYEN, T. D.; JUN, D.; MUSILEK, K.; KUCEROVA-CHLUPACOVA, M.; KUCA, K. From Pyridinium-based to Centrally Active Acetylcholinesterase Reactivators. Mini Rev. Med. Chem., 2014, vol. 14, p. 215–221. [ISSN  1389-5575], IF2012 = 2.865. DOI: 10.2174/1389557514666140219103138
  • JANĎOUREK, O.; DOLEŽAL, M.; PATEROVÁ, P.; KUBÍČEK, V.; PEŠKO, M.; KUNEŠ, J.; COFFEY, A.; GUO, J.; KRÁĽOVÁ, K. N-Substituted 5-amino-6-methylpyrazine-2,3-dicarbonitriles: Microwave-assisted synthesis and biological properties. Molecules, 2014, vol. 19, no. 1, p. 651–671. [ISSN 1420-3049], IF2013 = 2.095, doi: 10.3390/molecules19010651
  • SERVUSOVÁ, B.; MANDÍKOVÁ, J.; PATEROVÁ, P.; KUBÍČEK, V.; KUČERA, R.; DOLEŽAL, M.; ZITKO, J. Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation. Bioorg. Med. Chem. Lett., 2014, vol. 24, no. 2, p. 450–453. [ISSN 0960-894X] IF2012 = 2.338, doi: 10.1016/j.bmcl.2013.12.054

2013

  • JOSEPH, T.; VARGHESE, H. T.; PANICKER, C. Y.; VISWANATHAN, K.; DOLEŽAL, M.; MANOJKUMAR, T. K.; VAN ALSENOY, C. Vibrational spectroscopic (FT-IR, FT-Raman) investigations and computational study of N-(4-trifluoromethylphenyl)pyrazine-2-carboxamide. Spectrochim. Acta Part A, 2013, vol. 113, p. 203–214. [ISSN 1386-1425], IF2011 = 2.098
  • SPILOVSKA, K.; KORABECNY, J.; KRAL, J.; HOROVA, A.; MUSILEK, K.; SOUKUP, O.; DRTINOVA, L.; GAZOVA, Z.; SIPOSOVA, K.; KUCA, K. 7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer’s Disease Treatment - Synthesis, Biological Evaluation and Molecular Modeling Studies. Molecules, 2013, vol. 18, no. 2, p. 2397–2418. [ISSN 1420-3049], IF2012 = 2.428. doi:10.3390/molecules18022397
  • KOMLÓOVÁ, M.; HOROVÁ, A.; HRABINOVÁ, M.; JUN, D.; DOLEŽAL, M.; VINŠOVÁ, J.; KUČA, K.; MUSÍLEK, K. Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary acetylcholinesterase inhibitors. Bioorg. Med. Chem. Lett., 2013, vol. 23, no. 24, p. 6663–6666. [ISSN 0960-894X] IF2012 = 2.338, doi: http://dx.doi.org/10.1016/j.bmcl.2013.10.043
  • ZITKO, J.; SERVUSOVÁ, B.; PATEROVÁ, P.; MANDÍKOVÁ, J.; KUBÍČEK, V.; KUČERA, R.; HRABCOVÁ, V.; KUNEŠ, J.; SOUKUP, O.; DOLEŽAL, M. Synthesis, Antimycobacterial Activity and in Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides. Molecules, 2013, vol. 18, no. 12, p. 14807–14825. [ISSN 1420-3049], IF2012 = 2.428, doi: 10.3390/molecules181214807
  • Singh, N.; Karpichev, Y.; Gupta, B.; Satnami, M. L.; Marek, J.; Kuča, K.; Ghosh, K. K. Physicochemical Properties and Supernucleophilicity of Oxime Functionalized Surfactants: Hydrolytic Catalysts towards Dephosphorylation of Di- and Tri-phosphate Esters. J. Phys. Chem. B, 2013, vol. 117, no. 14, p. 3806–3817. [ISSN 1520-6106], IF2011= 3.696, DOI: 10.1021/jp310010q
  • Doležal, M.; Vobicková, J.; Servusová, B.; Paterová, P. Aminopyrazinoic acid esters as potential antimycobacterial drugs. Česk. Slov. Farm., 2013, vol. 62, no. 2, p. 84–88. [ISSN 1803-6597]
  • ZITKO, J.; PATEROVÁ, P.; KUBÍČEK, V.; MANDÍKOVÁ, J.; TREJTNAR, F.; KUNEŠ, J.; DOLEŽAL, M. Synthesis and antimycobacterial evaluation of pyrazinamide derivatives with benzylamino substitution. Bioorg. Med. Chem. Lett., 2013, vol. 23, no. 2, p. 476–479. [ISSN: 0960-894X], http://dx.doi.org/10.1016/j.bmcl.2012.11.052, IF2011 = 2.554
  • SERVUSOVÁ, B.; VOBICKOVÁ, J.; PATEROVÁ, P.; KUBÍČEK, V.; KUNEŠ, J.; DOLEŽAL, M.; ZITKO, J. Synthesis and antimycobacterial evaluation of N-substituted 5-chloropyrazine-2-carboxamides. Bioorg. Med. Chem. Lett., 2013, vol. 23, 3589–3591. [ISSN 0960-894X], DOI: 10.1016/j.bmcl.2013.04.021. IF = 2.554
  • OPLETALOVÁ V.; DOLEŽEL, J. Thiosemicarbazones and their antimycobacterial effects. Česk. Slov. Farm. 2013, vol. 62, 78–83. [ISSN 1803-6597]
  • OPLETALOVÁ, V.; KASTNER, P.; KUČEROVÁ-CHLUPÁČOVÁ, M.; PALÁT K. Study of hydrophobic properties of biologically active open analogues of flavonoids. J. Mol. Graph. Model. 2013, vol. 39, 61–64. DOI: 10.1016/j.jmgm.2012.07.009, [ISSN 1093-3263],  IF = 2.184

2012

  • SERVUSOVA, B.; EIBINOVA, D.; DOLEZAL, M.; KUBICEK, V.; PATEROVA, P.; PESKO, M.; KRALOVA, K. Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation. Molecules, 2012, vol. 17, no. 11, p. 13183–13198. [ISSN 1420-3049], IF2011 = 2.386. doi: 10.3390/molecules171113183
  • HOLAS, O.; MUSÍLEK, K.; POHANKA, M.; KUČA, K. The progress in the cholinesterase quantification methods. Exp. Opin. Drug Discov., 2012, vol. 7, no. 12, p. 12071223. [ISSN 1746-0441], DOI:10.1517/17460441.2012.729037, IF2011 = 2.116
  • HERICH, P.; KAMENÍČEK, J.; POHANKA, M.; HOLAS, O.; KOŽÍŠEK, J.; DLHÁŇ, L.; KUČA, K. Planar Ni(II) 1,2-dithiolenes involving tridentate P-donor ligands. J. Coordin. Chem., 2012, vol. 65, no. 1, p. 156164. [ISSN 0095-8972], DOI:10.1080/00958972.2011.644543, IF2011 = 1.547
  • MUSÍLEK, K.; KOMLÓOVÁ, M.; HOLAS, O.; HOROVÁ, A.; ŽĎÁROVÁ-KARASOVÁ, J.; KUČA, K. Myasthenia Gravis – Current Treatment Standards and Emerging Drugs, Chapter 3, p. 2342. In „A Look into Myasthenia Gravis“ by Joseph A. Pruitt (Ed.), 1st ed., Vienna, InTech, January 2012, 106 p. [ISBN: 978-953-307-821-2], DOI: 10.5772/31127. Available from: http://www.intechopen.com/books/a-look-into-myasthenia-gravis/myasthenia-gravis-current-treatment-standards-and-emerging-drugs
  • JANĎOUREK, O.; DOLEŽAL, M.; KLEMENTOVÁ, M.; KRÁĽOVÁ, K.; PEŠKO, M. Microwave assisted synthesis of new pyrazinamide analogues and their biological evaluation. The 16th International Electronic Conference on Synthetic Organic Chemistry, Presented in Section B, Bioorganic, Medicinal and Natural Products Chemistry, November, 1st – 30th, 2012. Published in 2013 by MDPI, Basel, Switzerland [ISBN: 3-906980-26-X], http://www.sciforum.net/presentation/1092
  • DOLEŽAL, M.; ZITKO, J.; JAMPÍLEK, J. Pyrazinecarboxylic acid derivatives with antimycobacterial activity. Chapter 10, p. 233–262. In “Understanding Tuberculosis - New approaches for fighting against drug-resistance“ by Pere-Joan Cardona (ed.), 1st ed., Vienna, InTech, February 2012, 376 p. [ISBN 978-953-307-948-6]
  • Małecki, J. G.; Maroń, A.; Serda, M.; Doležal, M.; Polański, J. Synthesis, characterization and molecular structure of Ru(II) complex with benzoylpyrazine carboxylic acid derivatives. Polyhedron, 2012, vol. 41, no. 1, 104–114. [ISSN 0277-5387], http://dx.doi.org/10.1016/j.poly.2012.04.033, IF2011 = 2.057
  • Joseph, T.; Varghese, H. T.; Panicker, C. Y.; Viswanathan, K.; Sundaraganesan, N.; Subramanian, N.; Doležal, M. Vibrational spectroscopic studies and computational study of 6-chloro-N-(4-trifluoromethylphenyl)-pyrazine-2-carboxamide. Glob. J. Anal. Chem., 2012, vol. 3, no. 18, p. 1–12. [ISSN 0976-5514]
  • ZITKO, J.; JAMPÍLEK, J.; DOBROVOLNÝ, L.; SVOBODOVÁ, M.; KUNEŠ, J.; DOLEŽAL, M. Synthesis and antimycobacterial evaluation of N-substituted 3-aminopyrazine-2,5-dicarbonitriles. Bioorg. Med. Chem. Lett., 2012, vol. 22, no. 4, p. 1598–1601. DOI: 10.1016/j.bmcl.2011.12.129, [ISSN 0960-894X], IF2011 = 2.554
  • DOLEŽAL, M. Přehled H1 antihistaminik určených nejen pro sezónní pylovou alergii. Prakt. Lékáren., 2012, vol. 8, no. 2, p. 55–61 . [ISSN 1801-2434]
  • DOLEŽAL, M. Perspektivy ve skupině návykových látek. Prakt. Lékáren., 2012, vol. 8, no. 4, p. 170–174. [ISSN 1801-2434]
  • Korábečný, J.; Hrubá, E.; Soukup, O.; Zemek, F.; Musílek, K.; Nepovímová, E.; Špilovská, K.; Opletalová, V.; Kuča, K. Zvažované farmakoterapeutické přístupy léčby Alzheimerovy choroby (Intended pharmacotherapeutical approaches of Alzheimer´s disease therapy). Čes. Slov. Farm., 2012, vol. 61, no. 1, p. 4–10. [ISSN 1210-7816]
  • Holas, O.; Musílek, K.; Horová, A.; Opletalová, V., Kamil, K. SAR Study on reactivators of ethyl-paraoxon inhibited acetylcholinesterase. Lett. Drug Des. & Discov., 2012, vol. 9, no. 6, p. 587–594. [ISSN 1570-1808], DOI:10.2174/157018012800673083, IF2011 = 0.872
  • Opletalová, V.; Doležel, J.; Buchta V.; Vejsová M.; Paterová. P. Antifungal Effects of (5Z)-5-Arylmethylidenerhodanines with a special view to the members of Mucorales. Folia Pharm. Univ. Carol. 2012, vol. 42, in press [ISSN 1210-9495]

2011

  • Opletalová, V.; Doležel, J.; Kráľová, K.; Peško, M.; Kuneš, J.; Jampílek, J. Synthesis and Characterization of (Z)-5-Arylmethylidene-rhodanines with Photosynthesis-Inhibiting Properties. Molecules 2011, vol. 16, no. 6, p. 5207–5227, [ISSN 1420-3049], DOI:10.3390/molecules16065207, IF2011 = 2.386
  • Korábečný, J.; Musílek, K.; Zemek, F.; Horová, A.; Holas, O.; Nepovímová, E.; Opletalová, V.; Hroudová, J.; Fišar, Z.; Jung, Y. S.; Kuča, K. Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties. Bioorg. Med. Chem. Lett., 2011, vol. 21, no. 21, p. 6563–6566, [ISSN 0960-894X], DOI: 10.1016/j.bmcl.2011.08.042, IF2011 = 2.554
  • Doležal, M.; Kráľová, K. Synthesis and evaluation of pyrazine derivatives with herbicidal activity. Chapter 27, p. 581–610. In "Herbicides, Theory and Applications" by Sonia Soloneski and Marcelo L. Larramendy (eds.), 27 chapters, 1st ed., Vienna, InTech, January 2011, 610 p. [ISBN 978-953-307-975-2]
  • TŮMOVÁ, L.; TŮMA, J.; Doležal, M. Pyrazinecarboxamides as potential elicitors of flavonolignan and flavonoid production in Silybum marianum and Ononis arvensis cultures in vitro. Molecules, 2011, vol. 16, no. 11, p. 9142–9152. [ISSN 1420-3049] DOI: 10.3390/molecules16119142, IF2011 = 2.386
  • Musílek, K.; Pavlíková, R.; Komlóová, M.; Holas, O.; Hrabinová, M.; Pohanka, M.; Dohnal, V.; Doležal, M.; Gunn-Moore, F.; Kuča, K. Preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors bearing but-(2E)-en-1,4-diyl connecting linkage. J. Enzym. Inhib. Med. Chem., 2011, vol. 26, no. 2, p. 245–253. [ISSN 1475-6366], IF2011 = 1.617
  • ZITKO, J.; DOLEŽAL, M.; Svobodová, M.; VEJSOVÁ, M.; Kuneš, J.; KUČERA, R.; JÍLEK, P. Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides. Bioorg. Med. Chem., 2011, vol. 19, no. 4, p. 1471–1476. [ISSN 0968-0896], IF2011 = 2.921
  • Musílek, K.; Komlóová, M.; Holas, O.; Hrabinová, M.; Pohanka, M.; Dohnal, V.; Nachon, F.; Doležal, M.; Kuča, K. Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage - Implications for early Myasthenia gravis treatment, Eur. J. Med. Chem., 2011, vol. 46, no. 1, p. 811–818. [ISSN 0223-5234], IF2011 = 3.346
  • Musílek, K.; Komlóová, M.; Holas, O.; Horová, A.; Pohanka, M.; Gunn-Moore, F.; Dohnal, V.; Doležal, M.; Kuča, K. Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage - Preparation, in vitro screening and molecular docking, Bioorg. Med.Chem., 2011, vol. 19, no. 1, p. 754–762. [ISSN 0968-0896], IF2011 = 2.921
  • Musílek, K.; Doležal, M.; Kuča, K.; Gunn-Moore, F. Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides. Med. Res. Rev., 2011, vol. 31, no. 4, p. 548–575. [ISSN 0198-6325], IF2011 = 10.700
  • Doležal, M.; Kešetovič, D.; Zitko, J. Antimycobacterial evaluation of pyrazinecarboxylic acid derivatives. Curr. Pharm. Design, 2011, vol. 17, no. 32, p. 3506–3514. [ISSN 1381-6128], IF2011 = 3.870
  • Musílek, K.; Röder, J.; Komlóová, M.; Holas; O., Hrabinová, M.; Pohanka, M.; Dohnal, V.; Opletalová, V.; Kuča, K.; Jung, J. S. Preparation, in vitro screening  and modelling: Analogues of SAD-128. Bioorg. Med. Chem. Lett., 2011, vol. 21, no. 1, p. 150–154, [ISSN 0960-894X], DOI: 10.1016/j.bmcl.2010.08.051, IF2011 = 2.554

 

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