Publication on drugs acting on vascular smooth muscles / Články na léčiva působí na hladký cévní sval

Research group of Cardiovascular and respirator pharmacology and toxicology

Dias P, Pourová J, Vopršalová M, Nejmanová I, Mladěnka P. 3-Hydroxyphenylacetic Acid: A Blood Pressure-Reducing Flavonoid Metabolite. Nutrients. 2022; 14(2):328 /IF₂₀₂₀=5.7/ (Q2_2020/AIS in Nutrition & Dietetics)
Migkos T, Pourová J, Vopršalová M, Auger C, Schini-Kerth V & Mladěnka P. Biochanin A, the most potent of 16 isoflavones, iBiochanin A, the most potent of 16 isoflavones, induces relaxation of the coronary artery through the calcium channel and cGMP-dependent pathway. Planta Medica 2020; 86(10): 708-716 /IF₂₀₁₈=2.7/
Najmanová I, Pourová J & Mladěnka P. Mixture of phenolic metabolites of quercetin can decrease elevated blood pressure of spontaneously hypertensive rats even in low doses. Nutrients 2020;12(1): 213 /IF₂₀₁₈=4.2/
Pourová J, Najmanová I, Vopršalová M, Migkos T, Pilařová V, Applová L, Nováková L & Mladěnka P. Two flavonoid metabolites, 3,4-dihydroxyphenylacetic acid and 4-methylcatechol, relax arteries ex vivo and decrease blood pressure in vivo. Vasc Pharmacol 2018;111: 36-43 /IF₂₀₁₇=3.6/
Porcu EP, Cossu M, Rassu G, Giunchedi P, Cerri G, Pourová J, Najmanová I, Migkos T, Pilařová V, Nováková L, Mladěnka P & Gavini E. Aqueous injection of quercetin: an approach for confirmation of its direct in vivo cardiovascular effects. Int J Pharmaceut 2018;541(1-2):224-233 /IF₂₀₁₆=3.6/
Najmanová I, Pourová J, Vopršalová M, Pilařová V, Semecký V, Nováková L & Mladěnka P. The flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rat. Mol Nutr Food Res 2016;60(5):981-91 /IF₂₀₁₄=4.6/
Najmanová I, Doseděl M, Hrdina R, Anzenbacher P, Filipský T, Říha M, Mladěnka P. Cardiovascular Effects of Coumarins Besides their Antioxidant Activity. Curr Top Med Chem. 2015;15(9):830-49 /IF₂₀₁₃=3.5/
Říha M, Vopršalová M, Pilařová V, Semecký V, Holečková M, Vávrová J, Palicka V, Filipský T, Hrdina R, Nováková L & Mladěnka P. Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity. Naunyn Schmiedeberg´s Arch Pharmacol 2014;387: 823-35 /IF₂₀₁₂=2.1/
Mladěnka P, Zatloukalová L, Filipský T, Hrdina R. Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity. Free Radic Biol Med. 2010;49(6):963-75 /IF₂₀₀₉=6.1/