Instrument: Microscale Thermophoresis

Department of Analytical Chemistry
Department of Biochemical Sciences
Department of Biophysics and Physical Chemistry
Department of Organic and Bioorganic Chemistry
Department of Pharmacognosy and Pharm. Botany
Department of Pharm. Chemistry and Pharm. Analysis
Department of Pharmaceutical Technology
Department of Pharmacology and Toxicology

Type: Monolith NT.115

Supplier	NanoTemper Technologies
Year of Purchase	2019
Amount (inc. VAT)	3.7 mil. CZK
Funding (only if EU-funded)	OP VVV⁏ CZ.02.1.01/0.0/0.0/16_019/0000841
Location	Department of Biochemical Sciences Room No. 2304
Responsible Person	prof. Ing. Vladimír Wsól, Ph.D.
Contact Person	doc. Ing. Petra Matoušková, Ph.D. (e-mail)

Photo of the instrument:

Regular Use of the Instrument:
The microscale thermophoresis is a highly sensitive technique based on the Soret effect that enables the quantitative analysis of molecular interactions in solution at the microliter scale. Binding constants can be determined e.g. for protein-protein, protein-DNA and protein-small molecule interactions.