Research funding

Skin barrier research group

Our research is supported by national, European and international funding programmes, with a strong emphasis on collaborative and early-career research projects.

Ongoing research projects

2026–2029 | ERA4Health NANOTECMED
Lipid replacement therapy for patients with congenital ichthyosis using topical acylceramide nanostructured delivery systems (LIPARCI II)

2025–2027 | Czech Science Foundation (GA ČR)
Understanding the mechanisms of epidermal lipid barrier formation, damage and repair: implications for skin diseases
25-17203S · with UCT Prague

2024–2027 | Czech Health Research Council (AZV)
Skin Barrier Lipidomics as a Noninvasive Method for Predicting Late Adverse Events in Childhood Cancer Survivors
NW24-08-00289

2024–2026 | Czech Science Foundation (GA ČR)
Corneocyte lipid envelope: lipid-protein binding mechanisms and barrier rescue in ichthyosis models
24-10736S

2024–2028 | MEYS / OP JAK
New Technologies for Translational Research in Pharmaceutical Sciences (NETPHARM)
CZ.02.01.01/00/22_008/0004607

Early-career researcher projects

2026–2029 | Charles University
Glucocorticoid-Mediated Remodeling of Skin Lipid Microstructure and Barrier Integrity
RTNS25-032 · Anna Paraskevopoulou

2025–2027 | Charles University
Study of the effects of micro and nanoplastics on the nanostructure and permeability of skin lipid barrier models
384725 · Ajit Pratihast

2025–2027 | Charles University
Restoring the damaged skin barrier: topical administration of barrier lipids and anti-inflammatory drugs
432825 · Filipa Pires de Castro

Completed research projects

2022–2025 | ERA-NET Cofund EuroNanoMed3 / TA ČR
Pre-clinical development of an acylceramide nanostructured delivery system to rescue the skin barrier in patients with ichthyosis (LIPARCI)

2022–2025 | Czech Science Foundation–German Research Foundation (GA ČR–DFG), Lead Agency
Novel Insights into the Nanostructure of the Skin Lipid Barrier by Biophysical Methods
22-20839K · with Daniel Huster, Leipzig University

2019–2022 | Operational Programme Research, Development and Education
Efficiency and Safety Improvement of Current Drugs and Nutraceuticals: Advanced Methods – New Challenges (EFSA-CDN)
CZ.02.1.01/0.0/0.0/16_019/0000841

2019–2022 | Operational Programme Research, Development and Education
Pre-application research into innovative medicines and medical technologies (InoMed)
CZ.02.1.01/0.0/0.0/18_069/0010046

2019–2021 | Czech Science Foundation–German Research Foundation (GA ČR–DFG)
Ultralong chain ceramides in membrane models of healthy and diseased skin barrier
19-09135J · with Daniel Huster, Leipzig University

2019–2021 | Czech Science Foundation (GA ČR)
Integrated design methodology of nanoformulation processes for (trans)dermal delivery of actives
19-09600S · with Jarmila Zbytovská, University of Chemistry and Technology Prague

2016–2018 | Czech Science Foundation–German Research Foundation (GA ČR–DFG)
Interdependencies between Inflammatory Processes and Barrier Lipids in Diseased Skin
16-25687J · with Sarah Hedtrich, Freie Universität Berlin

Completed early-career researcher projects

2022–2024 | Charles University
Lipid-covered gold nanoparticles as a model of human corneocyte lipid envelope
348222 · Sorina Hirbod

2021–2023 | Charles University
Synthesis and modification of surfaces as templates for skin barrier lipid assembly
262821 · Panagiota Velissari

2021–2022 | Charles University
Advanced topical delivery systems combining dendrimers and liposomes
274221 · Eleni Panoutsopoulou

2020–2022 | Charles University
Study of the effects of (patho)physiological conditions on the nanostructure and permeability of skin lipid barrier models
1156120 · Irene Sagrafena

2019–2021 | Charles University
Synthesis and study of the effects of ω-hydroxylated ceramides, both free and bound in the corneocyte lipid envelope, on skin barrier function
1194119 · Veronika Sommerová

2017–2019 | Charles University
Modulators of skin barrier function
184217 · Anna Nováčková