Previous Education and Employment
- 2002 Associate Professor in Pharmaceutical Technology, Faculty of Pharmacy in Hradec Králové
- 1984 CSc. degree, ibid.
- 1979 RNDr. degree, ibid.
- 1997 University teacher ibid.
- 1977 graduated pharmacist, ibid.
Research Interests
- Dosage forms
- Drug release and permeation of drug through biological membranes (dermal, pulmonary, rectal, sublingual)
- Nanodispersion systems, nanofiber drug carriers
Professional Memberships
- 2007 - 2015 member of the American Chemical Society, Colloid and Surface, Chemistry Section
- since 2002 Member of the Pharmaceutical Technology Section of Pharmacopoeia Board of the Ministry of Health of the Czech Republic
- 2004 - 2015 member of the European Association of Pharma Biotechnology
- 2003 - 2015 member of the European Federation of Biotechnology
- Since 1991 - member of the Czech Pharmaceutical Society of JEP
Teaching
- Since 2011 Chair of Subject-Area Board of Postgraduate Doctoral Studies in Pharmaceutical Technology
- Since 2008 Guarantor of the subjects Pharmaceutical Technology, Cosmetology for Pharmacists, Industrial Production of Pharmaceutical Preparations
- 2008 – 2011 Chair of Board of Rigorosal Studies in Pharmaceutical Technology
- Since 2004 –Advisor of Rigorosal Degree Thesis (6 thesis defended)
- Since 2004 Lecturer of Pharm. Technology at Qualified Persons Courses at
- Institute of Postgraduate Education in HealthCare, Prague
- Since 2000 Member of Scholarly Board of the Faculty of Pharmacy
- 2000 – 2011 Head of the Department of Pharmaceutical Technology
- Since 2000 Examiner´s Committee Member of the State Final Examination in Pharmacy
- Since 1996 – Supervisor of Post-Graduate students (4 thesis defended
- Since 1994 Member of Subject-Area Board of Pharmaceutical Technology)
- Since 1991 – Lecturer and examiner in Pharmaceutical Technology,
- Cosmetology for Pharmacists , and Industrial Production of Pharmaceutical Preparations
- Since 1985 – Advisor of Diploma Thesis (more than 100 diploma thesis students has defended)
- Since 1978 – Tutor of Practical Training and Seminary Tutor in Pharmaceutical Technology
Grants Received
Research Grants
- MPO project FR-TI1/436 - "Use of nanofiber membranes for the controlled release of active substances". Pharmaceutical part of the project. Principal investigator: Ing. Denisa Stránská, Elmarco Liberec. 2009 - 2012.
- Project MSM 0021620822 "Research of drug structures" Coordination of pharmaceutical-technological part of the roject. Principal investigator and director: Prof. RNDr. Rolf Karlíček, DrSc., Charles University in Prague, Faculty of Pharmacy in Hradec Králové. 2005 - 2011.
- MPO project FT-TA2/012 "Modulators transdermal permeation". Pharmaceutical-technological part of the project. Recipient: Ing. Michael Bartoš, VÚOS Pardubice VÚOS Pardubice/Fac. Pharm. Hradec Králové/Dep. Pharm. Technol. 2006 - 2008.
- MPO project 2A-1TP1/015 "New procedures and formulation of microdispersed nanodispersed lipid systems as transport systems of pharmacologically active substances". Pharmaceutical-technological part of the Project. Principal investigator: Dr. Jan Mikeska, PhD. Biomedica Prague / Dep. Pharm. Tech., Faculty of Pharmacy in Hradec Králové. 2007 - 2008.
- GAČR project 203/95/0602 "Salts of carbamic acids as transdermal penetration enhancers". Principal investigator 1995 -1998.
- Project MO AČR 114/3/93. "Transdermal administration of antidotes OFI".Principal investigator: 1993 - 1996.
Main Education Grant
Developmental Project MSMT 432 and Developmental Project MSMT 567„Harmonization of Doctoral Studies in Advanced Drug Delivery".Principal investigator 2005, 2006, 2007.
Awards/Prizes
Gold Medal, Brussels Eureka Expo '97 (Belgium) for the „Transdermal permeation accelerant Transkarbam 12“.
Publications
- Number of papers: 31 (SCOPUS)
- Number of citation: 276 (without autocitation, WoS)
- H index: 12
- Number of patents: 14
The most important publications in the last 3 years
VRBATA, P., BERKA, P., STRÁNSKÁ, D., DOLEŽAL, P., MUSILOVÁ, M., ČIŽINSKÁ, L. Electrospun drug loaded membranes for sublingual administration of sumatriptan and naproxen. Int. J. Pharm., 2013, 457, 168-176
VRBATA, P., BERKA, P., STRÁNSKÁ, D., DOLEŽAL, P., LÁZNÍČEK, M. Electrospinning of diosmin from aqueous solutions for improved dissolution and oral absorption. Int. J. Pharm. 2014, 473, 407-413.
The most important 5 patents:
1. Stránská D, Klabanová A, Doležal P, Vrbata P, Berka P, Musilová M: A carrier for oromucosal, especially sublingual administration of physiologically active substances, especially drugs. PCT/WO CZ 2011/000116 (2011)
2. Vávrová K, Doležal P, Hrabálek A: Pseudoceramides and pharmaceutical and / or cosmetic compositions designed for administration to the skin containing the same. WO 2007/147370 A2. (2007)
3. Hrabálek A, Doležal P, Farsa O, Krebs A, Kroutil A, Roman M, Šklubalová Z: ε-amino acid derivatives, processes of their preparation and use. U.S. Pat 6,187,938 (2001), Eur. Pat 0,973,710 B1 (2002)
4. Doležal P, Vachek J, Hrabálek A, Formánek J, Doležalová J.: Pharmaceutical composition for prophylactic and / or therapeutic transdermal administration of cholinesterase reactivators. CZ Pat. 282,476 (1997); Implemented in Czech Army, Special Chemical Troops as the preparation „Transant“.
5. Doležal P, Klimeš J, Sochor J, Korner J; Transdermal therapeutic system. CZ. Pat. 261,105 (1989)