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Assoc. Prof. PharmDr. Mgr. Martin Krátký, Ph.D.

Personal Profiles

Contact information:

Address:
Department of Organic and Bioorganic Chemistry, Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, CZ-50005 Hradec Králové, the Czech Republic

E-mail:
martin.kratky@faf.cuni.cz

Education

Habilitation

  • Charles University, Faculty of Pharmacy – Associate Professor in Pharmaceutical Chemistry (2019)

Doctoral Studies

Charles University in Prague, Faculty of Pharmacy, subject of study: Bioorganic Chemistry (Ph.D. degree obtained in February 2012) – Department of Inorganic and Organic Chemistry, supervisor: Prof. RNDr. Jarmila Vinšová, Ph.D., title of the thesis: Design and synthesis of compounds active especially against multidrug-resistant mycobacterial strains.

University

  • Charles University in Prague, Faculty of Pharmacy, subject of study: Pharmacy, final state exam in 2008 (summa cum laude) – master degree (Mgr., equivalent to MSc.)
  • Charles University in Prague, Faculty of Pharmacy – PharmDr. degree in Bioorganic Chemistry (2012)
  • University of Hradec Králové, Faculty of Education, subject of study: Upbringing and Education, Social Pedagogy Specialized in Ethopedy, final state exam in 2009 (summa cum laude) – master degree (Mgr.)
  • University of Hradec Králové, Faculty of Education, subject of study: Teacher of Secondary School, final state exam in 2010 – certificate in lifelong learning

Secondary School

  • Grammar School in Lanškroun, maturita (leaving) exam in 2003 (summa cum laude)

Professional qualifications and skills, professional membership

  • Teaching Qualification
  • Driving Licence
  • Computer Skills: advanced user
  • Language Skills: English (C1), German (B2), Latin (professional Latin)
  • Member of Czech Chemical Society (from 2009)
  • Training course in the interpretation of IR spectra (2009, 1 weak, organizer – Czech Spectroscopic Society)
  • Training course in the organocatalysis (2011, 1 weak, organizer – Zentiva company, prof. Pavel Kočovský)

Scientific grants

  • principal investigator of the Charles University Grant No. 27610/2010 Synthesis of novel salicylanilide prodrugs with potential antibacterial and antifungal activity (2010-2012)
  • Co-investigator of the Grant for the Development of Universities No. 665/G6 Synthesis of antimicrobial active benzanilide/salicylanilide derivatives (2012)
  • Co-investigator of the Charles University Grant No. 76807/2007 Modeling and synthesis of prodrugs of tuberculosis active compounds (2007-2009)
  • Pre-seed II UK (CZ.1.05/3.1.00/14.0299) – team member (2015)
  • principal investigator of the Czech Science Foundation grant number 17-27514Y “Peptide Drug Delivery Systems Targeting Macrophages for Antimycobacterial Active Compounds“ (2017-2019)
  • principal investigator of the Czech Science Foundation grant number 20-19638Y "Design and investigation of novel antimicrobial agents active against drug-resistant and biofilm forming gram-positive bacteria" (2020-2022)
  • co-investigator of the Czech Health Research Council (AZV ČR) project NU21-05-00482 "Experimental development of new antibacterial compounds and assessment of their potential towards combination therapy" (2021-2024)
  • co-investigator of the Czech Health Research Council (AZV ČR) project NU21-05-00446 "From hit-to-lead candidate – development of novel agents to combat tuberculosis" (2021-2024)

Interests

Research

  • synthesis of potential drugs and prodrugs active against tuberculosis, bacteria and fungi
  • design and synthesis of potential enzyme inhibitors (InhA, cholinesterases)
  • peptide drug delivery systems for antimycobacterial agents – synthesis and investigation of their properties
  • salicylanilides, their biological activities, mechanism of action, modifications

Personal

  • Scouting, self-education, botany, history, hiking, paddling, andragogy, accountancy of non-profit organizations

Work experience

  • senior lecturer/associate professor at the Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové (subjects: Laboratory Technique, General and Inorganic Chemistry, Organic Chemistry, Bioorganic Chemistry – laboratory trainings, seminars, selected lectures) – from 5/2016
  • Postdoc fellow at the Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University – 2012-2016 (grants Postdoc I CZ.1.07/2.3.00/30.0022 and TEAB – European project CZ.1.07/2.3.00/20.0235); topic: design, synthesis and evaluation of new antimicrobial active compounds and enzyme inhibitors
  • Teaching of pregradual students at the Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové (subjects Laboratory Technique, Organic and Bioorganic Chemistry – laboratory training, seminars) – 2008-2016
  • Researcher at the Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové – 2011 (full-time job), 2013-2015 (part-time job, employee of the grant Ministry of Health IGA NT 13346: Design and enzyme targeting of antibacterial active compounds against multidrug resistant strains)
  • Teaching of pregradual students at the Department of Chemistry, Faculty of Natural Sciences, J. E. Purkynje University in Ústí nad Labem (subjects related to toxicology) – 2015
  • Teaching of pregradual students at the Department of Chemistry, Faculty of Natural Sciences, University of Hradec Králové (subject Organic Chemistry) – 2012
  • Free time education and upbringing – different institutions, from 2002 till today (pedagogue, economist, medic)

Foreign experience

  • exchange scholarship at the Research Group of Peptide Chemistry, Eötvös Loránd University and Hungarian Academy of Science, Budapest, supervisor: Assoc. Prof. Szilvia Bösze, Ph.D. (9-12/2013 and 8-11/2014, 3/2018, 8/2018, 8/2019; topics: peptide synthesis and purification, peptide conjugates, cytotoxicity evaluation, cellular uptake studies)
  • Comenius University in Bratislava, Faculty of Natural Sciences, Department of Biochemistry, Slovakia; supervisor: Assoc. Prof. Katarína Mikušová, Ph.D. (6/2015; topics: working with mycobacteria, radioactive labels, investigation of potential mechanism of action of novel antimycobacterial drugs)

International cooperation

  • Assoc. Prof. Szilvia Bösze (Research Group of Peptide Chemistry, Hungarian Academy of Sciences, Budapest, Hungary)
  • Prof. Katarína Mikušová, Ph.D., and Assoc. Prof. Jana Korduláková, Ph.D. (Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia)

Other

  • supervisor, co-supervisor and reviewer of diploma, rigorosum and bachelor theses (Faculty of Pharmacy in Hradec Králové, Charles University; Department of Chemistry, Faculty of Science, J. E. Purkinje University in Ústí nad Labem)
  • external reviewer for scientific journals: European Journal of Medicinal Chemistry, Plos One, Saudi Journal of Biological Sciences, Arabian Journal of Chemistry, Current Medicinal Chemistry, Bioorganic and Medicinal Chemistry, Bioorganic and Medicinal Chemistry Letters, Chemical Papers, Journal of Microbiological Methods, Current Pharmaceutical Design, Research on Chemical Intermediates etc.

List of publications

  • Author of 63 original papers in journals with impact factor, 1 Czech patent, 1 international patent application, author or co-author of more than 90 conference contributions (posters, lectures including three invited lectures), co-author of one monograph and one book chapter
  • sum of the times cited: 800 (WOS; 24. 11. 2021)
  • Sum of citations excluding self-citations – 554
  • H-index: 17 (WOS; 24. 11. 2021)

Articles

1. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - BUCHTA, Vladimír. New amino acid esters of salicylanilides active against MDR-TB and other microbes. European Journal of Medicinal Chemistry, 2010, 45 (12), 6106-6113. ISSN 0223-5234. DOI 10.1016/j.ejmech.2010.09.040. IF2016 = 4.519

2. VINŠOVÁ, Jarmila - Imramovský, Aleš - KRÁTKÝ, Martin. An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation. Tetrahedron Letters 2010, 51 (1), 23-26. ISSN 0040-4039. DOI 10.1016/j.tetlet.2009.10.084. IF2016 = 2.193

3. Imramovský, Aleš - Férriz, Juana Monreal - PAUK, Karel - KRÁTKÝ, Martin. Synthetic Route for the Preparation of 2-Hydroxy-N-[1-(2-hydroxyphenylamino)-1-oxoalkan-2-yl]benzamides. Journal of Combinatorial Chemistry 2010, 12 (4), 414-416. DOI 10.1021/cc900168s. IF2012 = 4.933, now as ACS Combinatorial Science - IF2016 = 3.168

4. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Pokroky ve vývoji antituberkulotik působících na multilékově rezistentní kmeny. Chemické Listy 2010, 104 (11), 998-1005. ISSN 0009-2770. IF2016 = 0.387

5. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Antiviral Activity of Substituted Salicylanilides - A Review. Mini-Reviews in Medicinal Chemistry, 2011, 11 (11), 956-967. ISSN 1389-5575. DOI 10.2174/138955711797068382. IF2016 = 2.661

6. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Salicylanilide Ester Prodrugs as Potential Antimicrobial Agents - a Review. Current Pharmaceutical Design, 2011, 17 (32), 3494-3505. ISSN 1381-6128. DOI 10.2174/138161211798194521. IF2016 = 2.611

7. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - STOLARÍKOVÁ, Jirina. Antimycobacterial Assessment of Salicylanilide Benzoates including Multidrug-Resistant Tuberculosis Strains. Molecules, 2012, 17 (11), 12812-12820. ISSN 1420-3049. DOI 10.3390/molecules171112812. IF2016 = 2.861

8. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - GUISADO RODRIGUEZ, Nabila. Antimycobacterial Activity of Salicylanilide Benzenesulfonates. Molecules, 2012, 17 (1), 492-503. ISSN 1420-3049. DOI 10.3390/molecules17010492. IF2016 = 2.861

9. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - BUCHTA, Vladimír. In Vitro Antibacterial and Antifungal Activity of Salicylanilide Pyrazine-2-carboxylates. Medicinal Chemistry, 2012, 8 (4), 732-741. ISSN 1573-4064. DOI 10.2174/157340612801216346. IF2016 = 2.331

10. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Antifungal Activity of Salicylanilides and Their Esters with 4-(Trifluoromethyl)benzoic Acid. Molecules, 2012, 17 (8), 9426-9442. ISSN 1420-3049. DOI 10.3390/molecules17089426. IF2016 = 2.861

11. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - NOVOTNÁ, Eva. Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase. Tuberculosis, 2012, 92 (5), 434-439. ISSN 1472-9792. DOI 10.1016/j.tube.2012.06.001. IF2016 = 2.873

12. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - VOLKOVÁ, Marie. Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold. European Journal of Medicinal Chemistry, 2012, 50 (1), 433-440. ISSN 0223-5234. DOI 10.1016/j.ejmech.2012.01.060. IF2016 = 4.519

13. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - BUCHTA, Vladimír. In Vitro Antibacterial and Antifungal Activity of Salicylanilide Benzoates. The Scientific World Journal, 2012, 2012 (2012), nestránkováno. ISSN 1537-744X. DOI 10.1100/2012/290628. IF2013 = 1.219

14. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Advances in Mycobacterial Isocitrate Lyase Targeting and Inhibitors. Current Medicinal Chemistry, 2012, 19 (36), 6126-6137. ISSN 0929-8673. DOI 10.2174/092986712804485782. IF2016 = 3.249

15. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Antimycobacterial Activity of Quaternary Pyridinium Salts and Pyridinium N-oxides - Review. Current Pharmaceutical Design, 2013, 19 (7), 1343-1355. ISSN 1381-6128. DOI 10.2174/138161213804805711. IF2016 = 2.611

16. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - NOVOTNÁ, Eva. Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)benzoates. Molecules, 2013, 18 (4), 3674-3688. ISSN 1420-3049. DOI 10.3390/molecules18043674. IF2016 = 2.861

17. KRÁTKÝ, Martin - VOLKOVÁ, Marie - NOVOTNÁ, Eva. Synthesis and biological activity of new salicylanilide N,N-disubstituted carbamates and thiocarbamates. Bioorganic and Medicinal Chemistry, 2014, 22 (15), 4073-4082. ISSN 0968-0896. DOI 10.1016/j.bmc.2014.05.064. IF2016 = 2.93

18. RYCHTARCÍKOVÁ, Zuzana - KRÁTKÝ, Martin - GAZVODA, Martin. N-Substituted 2-Isonicotinoylhydrazinecarboxamides – New Antimycobacterial Active Molecules. Molecules, 2014, 19 (4), 3851-3868. ISSN 1420-3049. DOI 10.3390/molecules19043851. IF2016 = 2.861

19. VINŠOVÁ, Jarmila - KOZIC, Ján - KRÁTKÝ, Martin. Salicylanilide diethyl phosphates: Synthesis, antimicrobial activity and cytotoxicity. Bioorganic and Medicinal Chemistry, 2014, 22 (2), 728-737. ISSN 0968-0896. DOI 10.1016/j.bmc.2013.12.016. IF2016 = 2.93

20. VINŠOVÁ, Jarmila - KRÁTKÝ, Martin - KOMLÓOVÁ, Markéta. Diethyl 2-(Phenylcarbamoyl)phenyl Phosphorothioates: Synthesis, Antimycobacterial Activity and Cholinesterase Inhibition. Molecules, 2014, 19 (6), 7152-7168. ISSN 1420-3049. DOI 10.3390/molecules19067152. IF2016 = 2.861

21. KRÁTKÝ, Martin - NOVOTNÁ, Eva - SHALINI, Saxena. Salicylanilide Diethyl Phosphates as Potential Inhibitors of Some Mycobacterial Enzymes. The Scientific World Journal, 2014, 2014 (November), nestránkováno. ISSN 1537-744X. DOI 10.1155/2014/703053. IF2013 = 1.219

22. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - NOVOTNÁ, Eva. Salicylanilide pyrazinoates inhibit in vitro multidrug-resistant Mycobacterium tuberculosis strains, atypical mycobacteria and isocitrate lyase. European Journal of Pharmaceutical Sciences, 2014, 53 (March), 1-9. ISSN 0928-0987. DOI 10.1016/j.ejps.2013.12.001. IF2016 = 3.756

23. KRÁTKÝ, Martin - ŠTĚPÁNKOVÁ, Šárka - VORČÁKOVÁ, Katarína. Salicylanilide diethyl phosphates as cholinesterases inhibitors. Bioorganic Chemistry, 2015, 58 (February), 48-52. ISSN 0045-2068. DOI 10.1016/j.bioorg.2014.11.005. IF2016 = 3.231

24. KRÁTKÝ, Martin - MANDÍKOVÁ, Jana - TREJTNAR, František. Synthesis and antimicrobial activity of sulphamethoxazole-based ureas and imidazolidine-2,4,5-triones. Chemical Papers, 2015, 69 (8), 1108-1117. ISSN 0366-6352. DOI 10.1515/chempap-2015-0109. IF2016 = 1.258

25. BARANYAI, Zsuzsa - KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates. European Journal of Medicinal Chemistry, 2015, 101 (August), 692-704. ISSN 0223-5234. DOI 10.1016/j.ejmech.2015.07.001. IF2016 = 4.519

26. KRÁTKÝ, Martin - BOSZE, Szilvia - BARANYAI, Zsuzsa. Synthesis and in vitro biological evaluation of 2-(phenylcarbamoyl)phenyl 4-substituted benzoates. Bioorganic and Medicinal Chemistry, 2015, 23 (4), 868-875. ISSN 0968-0896. DOI 10.1016/j.bmc.2014.12.019. IF2016 = 2.93

27. PARASKEVOPOULOS, Georgios - KRÁTKÝ, Martin - MANDÍKOVÁ, Jana. Novel derivatives of nitro-substituted salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. Bioorganic and Medicinal Chemistry, 2015, 23 (22), 7292-7301. ISSN 0968-0896. DOI 10.1016/j.bmc.2015.10.029. IF2016 = 2.93

28. ŠVARCOVÁ, Markéta - KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Investigation of Potential Inhibitors of Chorismate-Utilizing Enzymes. Current Medicinal Chemistry, 2015, 22 (11), 1383-1399. ISSN 0929-8673. DOI 10.2174/0929867322666150209152446. IF2016 = 3.249

29. KRÁTKÝ, Martin - ŠTĚPÁNKOVÁ, Šárka - VORČÁKOVÁ, Katarína. Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates. Molecules, 2016, 21 (2), nestránkováno. ISSN 1420-3049. DOI 10.3390/molecules21020191. IF2016 = 2.861

30. KRÁTKÝ, Martin - ŠTĚPÁNKOVÁ, Šárka - VORČÁKOVÁ, Katarína. Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors. Bioorganic Chemistry, 2016, 68 (October), 23-29. ISSN 0045-2068. DOI 10.1016/j.bioorg.2016.07.004. IF2016 = 3.231

31. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Sulphur-Containing Heterocycles as Antimycobacterial Agents: Recent Advances in Thiophene and Thiadiazole Derivatives. Current Topics in Medicinal Chemistry, 2016, 16 (26), 2921-2952. ISSN 1568-0266. DOI 10.2174/1568026616666160506131118. IF2016 = 2.561

32. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila. Salicylanilide N-monosubstituted carbamates: Synthesis and in vitro antimicrobial activity. Bioorganic and Medicinal Chemistry, 2016, 24 (6), 1322-1330. ISSN 0968-0896. DOI 10.1016/j.bmc.2016.02.004. IF2016 = 2.93

33. Paraskevopoulos, Georgios - Monteiro, Sara - Vosátka, Rudolf - Krátký, Martin. Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. Bioorganic and Medicinal Chemistry 2017, 25 (4), 1524-1532. ISSN 0968-0896. DOI 10.1016/j.bmc.2017.01.016. IF2016 = 2.93

34. Krátký, Martin - STOLAŘÍKOVÁ, Jiřina - VINŠOVÁ, Jarmila. Antimicrobial activity of rhodanine-3-acetic acid derivatives. Bioorganic and Medicinal Chemistry 2017, 25 (6), 1839-1845. ISSN 0968-0896. DOI 10.1016/j.bmc.2017.01.045. IF2017 = 2.881

35. Krátký, Martin - STOLAŘÍKOVÁ, Jiřina - VINŠOVÁ, Jarmila. Novel Sulfamethoxazole Ureas and Oxalamides as Potential Antimicobacterial Agents. Molecules 2017, 22 (4), 535. ISSN 1420-3049. DOI 10.3390/molecules22040535. IF2016 = 2.861

36. KRÁTKÝ, Martin - VINŠOVÁ, Jarmila - ŠTĚPÁNKOVÁ, Šárka. Novel Fluorophenylalanine Derivatives: Synthesis and Investigation of Their Biological Activity. Bioorganic Chemistry 2017, 71, 244-256 . ISSN: 0045-2068.DOI 10.1016/j.bioorg.2017.02.010. IF2017 = 3.929

37. BARANYAI, Zsuzsa - KRÁTKÝ, Martin - Vosátka, Rudolf. In vitro biological evaluation of new antimycobacterial salicylanilide-tuftsin conjugates. European Journal of Medicinal Chemistry  2017, 133, 152-173. ISSN 0223-5234. DOI: 10.1016/j.ejmech.2017.03.047. IF2017 = 4.816

38. Krátký M., Bősze S., Baranyai Zs., Stolaříková J., Vinšová J. Synthesis and biological evolution of hydrazones derived from 4-(trifluoromethyl)benzohydrazide. Bioorg. Med. Chem. Lett. 2017, 27, 5185-5189. IF2017 = 2.442

39. Krátký M., Dzurková M., Janoušek O., Konečná K., Trejtnar F., Stolaříková J., Vinšová J. Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity. Molecules 2017, 22, 1573. IF2017 = 3.098

40. Krátký M., Stolaříková J., Vinšová J. Novel Sulfamethoxazole Ureas and Oxalamides as Potential Antimycobacterial Agents. Molecules 2017, 22(4), 535. IF2017 = 3.098

41. Paraskevopoulos G., Monteiro S., Vosátka R., Krátký M., Navrátilová L., Trejtnar F., Stolaříková J., Vinšová J. Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. Bioorg. Med. Chem. 2017, 25(4), 1524-1532. IF2017 = 2.881

42. Krátký M., Vorčáková K., Vinšová J., Štěpánková Š. Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase, Bioorganic Chemistry 2018, 80, 668-673. IF2017 = 3.929

43. Vosátka R., Krátký M., Švarcová M., Janoušek J., Stolaříková J., Madacki J., Husza  S., Mikušová K., Korduláková J.,Trejtnar F., Vinšová J. New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action. Eur. J. Med. Chem. 2018, 151, 824-835. IF2017 = 4.816

44. Vosátka R., Krátký M., Vinšová J. Triclosan and its derivatives as antimycobacterial active agents Eur. J. Pharm. Sci. 2018, 114, 318–331. IF2016 = 3.466

45. Krátký M., Štěpánková Š., Houngbedji Neto-Honorius, Vosátka R., Vorčáková K., Vinšová J. 2-Hydroxy-N-phenylbenzamides and their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase. Biomolecules 2019, 9, 698. IF2019 = 4.082

46. Krátký M., Janďourek O., Baranyai Zs., Novotná E., Stolaříková J., Bősze S., Vinšová J. Phenolic N-monosubstituted carbamates: Antitubercular and toxicity evaluation of multi-targeting compounds. Eur. J. Med. Chem. 2019, 181, 111578. IF2019 = 5.572

47. Krátký M., Baranyai Z., Štěpánková Š., Svrčková K., Švarcová M., Stolaříková J., Horváth L., Bősze S., Vinšová J. N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1- carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity. Molecules 2020, 25, 2268. IF2020 = 4.411

48. Krátký M., Konečná K., Janoušek J., Brablíková M., Janďourek O., Trejtnar F., Stolaříková J., Vinšová J. 4-Aminobenzoic acid derivatives: Converting folate precursor to antimicrobial and cytotoxic agents. Biomolecules 2020, 10, 9, 1-21. IF2020 = 4.879

49. Krátký M., Jaklová K., Štěpánková Š., Svrčková K., Pflégr V., Vinšová J. N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors. Curr. Top. Med. Chem. 2020, 20(23), 2094-2105. IF2020 = 3.295

50. Krátký M., Štěpánková Š., Brablíková M., Svrčková K. Švarcová M., Vinšová J. Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors. Curr. Top. Med. Chem. 2020, 20, (23), 2106-2117. IF2020 = 3.295

51. Krátký M., Konečná K., Janoušek J., Janďourek O., Maixnerová J., Kalivodová S., Trejtnar F., Vinšová J. Sulfonamide-salicylaldehyde imines active against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci. Future Med. Chem. 2021, 13(22),1945-1962. IF2020 = 3.808

52. Krátký M., Vu Q. A., Štěpánková Š., Maruca A., Silva T. B., Pflégr V., Ambrož M., Rocca R., Vorčáková K., Alcaro S., Borges F., Vinšová J. Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study. Bioorg. Chem. 2021, 116, 105301. IF2020 = 5.275

53. Pflégr V., Horváth L., Stolaříková J., Pál A., Korduláková J., Bősze S., Vinšová J., Krátký M. Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity. Eur. J. Med. Chem. 2021, 223(5), 113668. IF2020= 6.514

54. Krátký M., Konečná K., Brablíková M., Janoušek J., Pflégr V., Maixnerová J., Trejtnar F., Vinšová J. Iodinated 1,2-diacylhydrazines, benzohydrazide-hydrazones and their analogues as dual antimicrobial and cytotoxic agents. Bioorg. Med. Chem. 2021, 41, 116209. IF2020 = 3.641

55. Baranyai, Z., Biri-Kovács B., Krátký M., Szeder B., Debreczeni M.L., Budai J., Kovács B., Horváth L., Pári E., Németh Z., Cervenak L., Zsila F., Méhes E., Kiss E., Vinšová J., Bosze, S. Cellular internalization and inhibition capacity of new anti-glioma peptide conjugates: Physicochemical characterization and evaluation on various monolayer- and 3D spheroid-based in vitro platforms. J. Med. Chem. 2021, 64, 6, 2982–3005. IF2020 = 7.446

56. Veena S. Kumar, Y. Shyma Mary, Krátký M., Vinsova J., Baraldi C., Roxy M.S., Gamberini M.C. Spectroscopic investigations, concentration dependent SERS, and molecular docking studies of a hydroxybenzylidene derivative. Journal of Biomolecular Structure and Dynamics 2021. IF2018 = 3.31

57. Y. Sheena Mary, Y.Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. DFT, molecular docking and SERS (concentration and solvent dependant) investigations of a methylisoxazole derivative with potential antimicrobial activity. Journal of Molecular Structure 2021, 1232, 130034. IF2020 = 3.196

58. Krátký M., Svrčková K, Vu Q. A., Štěpánková Š., Vinšová J. Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase. Molecules 2021, 26, 989. IF2020 = 4.411

59. Y. Sheena Mary, Y. Shyma Mary, Armaković S., Armaković S.J, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. Concentration and solvent dependent SERS, DFT, MD simulations and molecular docking studies of a thio xothiazolidine derivative with antimicrobial properties. Journal of Molecular Liquids, 2021, 329, 115582. IF2020 = 6.165

60. Krátký M., Konečná K., Brokešová K., Maixnerová J., Trejtnar  F., Vinšová J. Optimizing the structure of (salicylideneamino)benzoic acids: Towards selective antifungal and anti-staphylococcal agents, Eur. J. Pharm. Sci. 2021, 159, 105732. IF2020 = 4.384

61. Y. Sheena Mary, Y. Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. Concentration dependent SERS, DFT and molecular docking studies of a ureido derivative with antitubercular properties. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 249, 2021, 119329. IF2019 = 3.232

62. Y. Sheena Mary, Y. Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. DFT, SERS-concentration and solvent dependent and docking studies of a bioactive benzenesulfonamide derivative Journal of Molecular Structure  2021, 1228, 129680. IF2020 = 3.196

63. Gamberinia M. C., Y. Shyma Mary, Y. Sheena Mary, Krátký M., Vinsova J., Baraldi C. Spectroscopic investigations, concentration dependent SERS, and molecular docking studies of a benzoic acid derivative. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2021, 248(5), 119265. IF2020 = 4.098

Others

UNIVERZITA KARLOVA V PRAZE, FARMACEUTICKÁ FAKULTA V HRADCI KRÁLOVÉ. Substituovaný derivát kyslíkatých kyselin fosforu, jeho použití a farmaceutický prípravek ho obsahující. Puvodce: Vinšová, Jarmila - Krátký, Martin - Paraskevopoulos, Georgios. patent c. 305738 udelen 13.01.2016.

UNIVERZITA KARLOVA V PRAZE, FARMACEUTICKÁ FAKULTA V HRADCI KRÁLOVÉ. Substituted derivative of oxyphosphorus acids, its use and pharmaceutical preparation containing it. Inventors: Vinšová, Jarmila - Krátký, Martin - Paraskevopoulos, Georgios. Patent application No. WO 2016095878 A1 (published 23.6.2016).

VINŠOVÁ, Jarmila - KRÁTKÝ, Martin. Tuberculosis — The Development of New MDR-TB Drugs. In: Drug-Resistant Tuberculosis: Causes, Diagnosis and Treatments. 1 vyd. New York: Nova Biomedical, 2009, neuvedeno, s. 59-141. ISBN 978-1-60876-055-8.

VINŠOVÁ, Jarmila - KRÁTKÝ, Martin. Development of New MDR-Tuberculosis Drugs. 1 vyd. New York: Nova Biomedical, 2010. 100 s. s. ISBN 978-1-6168-233-0.

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