PharmDr. Eva Šnejdrová, Ph.D.

Teaching activities

• Pharmaceutical Technology I and II
• Physical Principles of Dosage Forms
• Selected Methods of Pharmaceutical Technology
• Mentor of more than 70 defended diploma thesis
• Consultant of more than 30 rigorous thesis
• Mentor and consultant of postgradual students 

Research interests

• Formulation and testing of Film Forming Systems (FFS) for local drug delivery
• Synthesis, characterization, and degradation studies of PLGA-based polyesters of branched architecture
• Formulation and characterization of drug loaded biodegradable micro and nanoparticles (Malvern Mastersizer 3000, Zetasizer nano ZS Malvern - particle size, PDI, zeta-potential; encapsulation efficiency; dissolution testing)
• Formulation and testing of PLGA based implantable DDS of the ISFI type, solid dispersions and thin layers (melting method, solvent method, plasticization)
• Rheological behaviour of coating dispersions, polymers, pharmaceutical semisolid excipients and preparations, plasticized polyesters (absolute rheometer Kinexus Pro⁺ Malvern - rotational, oscillation and creep tests)
• Dissolution testing (USP 1, 2, 4)
• In vitro testing of mucoadhesion by tensile tests (rheometer Kinexus Pro⁺Malvern, material testing machine Zwick/Roell), and "wash out" tests
• Thermal analysis of drugs, pharmaceutical excipients, polymeric systems (DSC 200 F3 Maia Netzsch)

Grants and Memberships

• Bio2Brain Consortium under the EU's H2020 Programme, EC Grant Agreement number 956977
  Study of the dynamics of gene regulation by nuclear receptors: understanding detoxification functions and contribution to the optimization of pharmacotherapy, Grant Agency of the Czech Republic, (Project ID: GA17-06841S), Project duration: 01.01.2017 - 31.12.2019

• Member of CCS's Expert Group of Rheology
  Member of Commission for Rigorosum Examination in the field of Pharmaceutical Technology
  AS Faf UK Economic Commission
  Academic Senate Faf UK 2013 – 2021 chairwoman of the Economic Committee

Collaboration

Industry

• Teva Czech Industries s.r.o.
• Zentiva Group, a.s.
• ​Dr. Müller Pharma s.r.o. 
• Contipro a.s.

Academic sphere

• Federal State Autonomous Educational Institution of Higher Education Belgorod State National Research University, Russion Union
• University of Szeged, Institute of Pharmaceutical Technology and Regulatory Affairs, Hungary
• MBS College of Crete, Greece

• Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy – Medical College Jagiellonian University, Poland

Publications

Snejdrova, E., Loskot, J., Veris, A.,Kastner, P., Andrys, R., Formulation study of PLGA in situ films for topical delivery of salicylates. Eur. J. Pharm. Sci. 2024, 199, 114282, ISSN 0939-6411, IF₂₀₂₃ 4.9; Q2, W2, https://doi.org/10.1016/j.ejpb.2024.114282

Mrštná, K., Matoušková, K., Matouš, P., Matysová, L., Švec, F., Šnejdrová, E., Krčmová, L. K.: Analysis of terbinafine in PLGA-based drug delivery systems by a fast and sensitive UHPLC-DAD method. Anal. Methods, 2023, 15, 2823-2832. IF  3.532; Q2; W2  https://doi.org/10.1039/D3AY00506B

Prokes, L.; Snejdrova, E.; Soukup, T.; Malakova, J.; Frolov, V.; Loskot, J.; Andrys, R.; Kucera, T. Allogeneic Bone Impregnated With Biodegradable Depot Delivery Systems for the Local Treatment of Joint Replacement Infections: an In Vitro Study. Molecules 2022, 27, 6487-6502 https://doi.org/10.3390/molecules27196487  IF₂₀₂₁: 4.927; Q2

Komersova, A.; Svoboda, R.; Skalicka, B.; Bartos, M.; Snejdrova, E.; MuzIkova, J.; Matzick, K. Matrix Tablets Based on Chitosan–Carrageenan Polyelectrolyte Complex: Unique Matrices for Drug Targeting in the Intestine. Pharmaceuticals 2022, 15, 980. IF 5.215 Q1 https://doi.org/10.3390/ph15080980

Snejdrova, E., Loskot, J., Martiska, J., Soukup, T., Prokes, L., Frolov, V., Kucera, T., Rifampicin-loaded PLGA nanoparticles for local treatment of musculoskeletal infections: Formulation and characterization. Journal of Drug Delivery Science and Technology 2022, 73 103435. IF 5.062, Q1 https://doi.org/10.1016/j.jddst.2022.103435

Muzikova, J.; Snejdrova, E.; Martiska, J.; Doubkova, B.; Veris, A. A Study of Compressibility, Compactability and Mucoadhesivity of Tableting Materials for Matrix Systems Based on Chitosan. Polymers 2021, 13, 3636. IF 4.329 Q1 https://doi.org/10.3390/polym13213636

Snejdrova, E., Martiska, J., Loskot, J., Paraskevopoulos, G., Kovacik, A., Regdon JR., G., Budai-Szucs, M., Palat, K., Konecna, K. PLGA based film forming systems for superficial fungal infections treatment, Eur. J. Pharm. Sci. 2021, 136, 13p. Q2, IF₂₀₂₀ 4.384, ISSN 0928-0987 https://doi.org/10.1016/j.ejps.2021.105855

Snejdrova, E., Podzimek, S., Martiska, J., Holas, O., Dittrich, M. Branched PLGA derivatives with tailored properties for drug delivery, Acta Pharmaceutica 2020, https://doi.org/10.2478/acph-2019-0031, https://content.sciendo.com/view/journals/acph/70/1/article-p63.xml

Martiska, J., Snejdrova, E., Drastik, M., Matysova, L., Dittrich, M., Loskot, J., Jilek, P. Terbinafine-loaded branched PLGA-based cationic nanoparticles with modifiable properties, Pharmaceutical Development and Technology 2019, 24, 10, 1308-1316 DOI: 10.1080/10837450.2019.1667387, https://www.tandfonline.com/doi/full/10.1080/10837450.2019.1667387

Siska, B., Snejdrova, E., Machac, I., Dolecek, P., Martiska, J.  (2019) Contribution to the rheological testing of pharmaceutical semisolids, Pharmaceutical Development and Technology, 24:1, 80-88, https://doi.org/10.1080/10837450.2018.1425432

Snejdrova, E., Dittrich, M. Pharmaceutically used plasticizers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 45-68. ISBN 978-953-51-0363-9. DOI: 10.5772/39190
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutically-used-plasticizers-

Snejdrova, E., Dittrich, M. Pharmaceutical applications of Plasticized Polymers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 69-90. ISBN 978-953-51-0363-9. DOI: 10.5772/36543
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutical-applications-of-plasticized-polymers