Workshop | Program

Secondary metabolites of plants as potential drugs

Book of Abstracts

Thursday, 23 June, 2022

8:30-9:15
Registration

9:15-9:30
Opening of the Workshop by Dean of the Faculty and organizers
prof. Lucie Cahlíková, prof. Karel Šmejkal

9:30-9:45
Introduction – Presentation Research Infrastructure Efficiency and Safety Improvement of Current Drugs and Nutraceuticals: Advanced Methods – New Challenges (EFSA–CDN)

Lectures (Chair Prof. Karel Šmejkal)

9:45-10:20
HPLC-Based approaches for the analysis of naturally occurring cannabinoids
Prof. Satyajit Sarker

10:20-10:55
Phytochemical analysis of Cannabis sativa L. products on the market: what do we have on our hands today?
Prof. Stefano Dall´Acqua

10:55-11:20
Chromatographic methods for the analysis of nutraceuticals based on plant extracts and their quality control in the Czech market
Prof. Dalibor Šatínský

11:20-11:50 Cofee break

Lectures and short lectures (Chair Prof. Dalibor Šatínský)

11:50-12:25
Natural products as drug leads for neutrophilic inflammatory diseases – on-line lecture
Prof. Tsong-Long Hwang

12:25-12:40
Isolation and identification of geranylated flavonoids from Paulownia tomentosa Steud. fruit and their anti-inflammatory activities
Dr. Lenka Molčanová

12:45-13:00
Selective inhibitory effects of tropical plant extracts and compounds on diarrheagenic bacteria and intestinal cancer cells
Dr. Tomáš Kudera

13:00-14:00 Lunch break

Lectures (Chair Prof. Stefano Dall´Acqua)

14:00-14:35
Challenges of phenolic compounds analysis in herbal drugs and preparations
Prof. Franz Bucar

14:35-15:00
Recent advances in antimicrobial susceptibility testing of plant-derived volatile agents in vapour phase
Prof. Ladislav Kokoška

15:00-15:20
Progress and trends in potential utilization of natural compounds as drugs - prenylated phenolics
Prof. Karel Šmejkal

15:20-15:35
Citrus bergamia, isolation of compounds with LDLR and PCSK9 modulation properties, a food source of hypocholesterolemic agents
Dr. Stefania Sut

15:35-15:50
Study of cytostatic, cytotoxic and proapoptotic activity of Amaryllidaceae alkaloid montanine
Dr. Radim Havelek

15:50-16:05
Development and Production of LC Columns in the Chromservis Company
Ing. Jana Volková

16:05-19:00
Coffee, small refreshment accompanied by practical demonstration of HPTLC analysis of secondary metabolites and 3D print of the structure of narcissidine

16:05-19:00
Poster section

17:00-19:00
Excursion to the Garden of Medicinal plants and Greenhouse (English group, Czech group)

19:00 Closing of the first day of Workshop

Friday, 24 June, 2022

Lectures and short lectures (Chair Prof. Vincenza Andrisano)

9:00-9:35
Large scale isolation and semi-synthesis of bioactive compounds from Olea europaea
Prof. Leandros Scaltsounis

9:35-10:00
Isoquinoline alkaloids and their derivatives as a new class of antimycobacterial drugs
Prof. Lucie Cahlíková

10:00-10:20
Ambelline derivatives as selective inhibitors of liver stage malaria in vitro
Dr. Kateřina Hradiská Breiterová

10:20-10:35
Ficus species: comparison of phytochemical profile and isolation of dominant compounds
Dr. Milan Malaník

10:35-11:00 Coffee break

Lectures and short lectures (Chair. Prof. Lucie Cahlíková)

11:00-11:35
Integrated analytical methodologies for Alzheimer's disease drug discovery
Prof. Vincenza Andrisano

11:35-11:55
Alkaloids of norbelladine type from Narcissus pseudonarcissus cv. Carlton as inspiration for development of highly selective butyrylcholinesterase inhibitors
Dr. Abdullah al Mamun

11:55-12:15
Biological study of indole alkaloid from Vinca minor L. with anti-alzheimer´s potential
Dr. Rudolf Vrabec

12:15-12:35
Isolation of alkaloids from Geissospermum vellosii and their biological activity
Dr. Marcela Šafratová

12:35-12:50
Bioguided analysis of Papaver rhoeas as a source of potential biologically active alkaloids
Dr. Jaroslav Jenčo

12:50-14:00 Lunch Break

Lectures and short lectures (Chair. Prof. Franz Bucar)

14:00-14:35
Gut microbiota need to be considered for explaining the activity of herbal medicine
Prof. Rudolf Bauer

14:35-14:55
Santorini’s main food crops agricultural side-products with bioactivity potential: “Fava” and the “Santorini cherry tomato”
Dr. Konstantina Vougogiannopoulou

14:55-15:15
Alkaloids isolated from Croton linearis Jacq. leaves: their antiprotozoal potentiality.
Dr. Jesús García Díaz

15:15-15:35
Discovery of new structural features in natural products
Dr. Jana Křoustková

15:35-17:30
Coffee, small refreshment accompanied by practical demonstration of HPTLC analysis of secondary metabolites and 3D print of the structure of narcissidine

17:30-22:00
Workshop´s disscussion evening

Program change reserved.

Speakers

Confirmed speakers

Overview of poster presentations

Determination of in vitro growth-inhibitory effect of essential oils from Indian medicinal plants against respiratory tract pathogens using new broth macrodilution volatilization method
Aishwarya Chaure
Evaluation of anti-bacterial activity of semi-synthetic alkaloid derivatives from medicinal plants of the Amaryllidaceae family
Adéla Diepoltová
Susceptibility of intestinal bacteria involved in colorectal cancer pathogenesis to phytochemicals and their synthetic analogs in vitro
Barbora Fišerová
Liquid matrix volatilization methods for susceptibility testing of respiratory bacteria to volatile agents in vapour phase
Markéta Houdková
Investigation of the phytochemical and cancer chemopreventive potential of Claoxylon longifolium leaves growing in southern Thailand
Chuanchom Khuniad
Discovery of anti-coronavirus bisbenzylisoquinoline alkaloids
Michal Kořínek
Discovery of a Series, Novel Oleocanthal - Based compounds as Potent Anticancer Agents
Ioannis K. Kostakis
Investigation of selected biological activities of montanine-type alkaloids and their derivatives
Negar Maafi
Advanced chromatographic approaches in phenolic compounds profiling in archive Tokaj wines
Pavlína Moravcová
Celecoxib potentiates the in vitro anti-staphylococcal effect of oxacillin
Onyedika Emmanuel Okpala
Amaryllidaceae alkaloids as inspiration for the development of highly selective butyrylcholinesterase inhibitors: the relationship between structure, effect, and toxicity
Filip Pidaný
Nature mimicking drug design of spiro-2-oxindoles with 4H-pyran and chromen cores
Ruslan Redkin
Semi-synthetic derivatives of Amaryllidaceae alkaloid ambelline as potential lead structures for drug development
Aneta Ritomská
Exploitation of Greek medical and aromatic plants for the production of edible products
Konstantina Vougogiannopoulou
An innovative and high nutritional value cheese product, enriched with bioactive extracts of olive by-products
Konstantina Vougogiannopoulou
Production of meat products enriched with olive biophenols
Konstantina Vougogiannopoulou
Alkaloids of Dicranostigma franchetianum (Papaveraceae) and their antimycobacterial activity
Viriyanata Wijaya