Research funding

Development of new potential drugs with antimicrobial activity

Ongoing

  • 2019-2021 Czech Science Foundation (GA ČR)20-19638Y
  • 2017-0219 Czech Science Foundation (GA ČR): GJ17-27514Y

Past (since 2010)

  • 2012-2015 - Ministry of Health IGA NT 13346: Design and enzyme targeting of antibacterial active compounds against multidrug resistant strains. (principle investigator Vinšová J.)
  • 2012-2015 - FAFIS - European project (CZ.1.07/2.2.00/28.0194)
  • 2012-2015 – TEAB – European project (CZ. 1.07/2.3.00/20.0235)
  • 2010-2011 - Bilateral project “Kontakt” Czech Republic - Slovenia: Development of novel antituberculosis agents and prodrugs effective against multidrug resistant tuberculosis. (principle investigator Vinšová J.)
  • 2009-2011 - Ministry of Health IGA NS 10367-3: Evaluation and development of new perspective antimycobacterial drugs and prodrugs active against multidrug resistant strains. (principle investigator Vinšová J.)

Student projects

  • 2010-2012 - GAUK 27610: Synthesis of novel salicylanilide prodrugs with potential antibacterial and antifungal activity. (investigators: Krátký M., Rychtarčíková Z.)
  • 2012 - FRVŠ 665/G6 Synthesis of antimicrobial active anilide/salicylanilide derivatives (investigators Kozic J., Krátký M.)

Development of new antituberculosis drugs

Ongoing

Past (since 2010)

  • 2015-2017: Project GAUK (361215) - Synthesis of potential antituberculotics and their in vitro and in vivo evaluation (Syntéza potenciálních antituberkulotik a jejich hodnocení in vitro a in vivo)
  • 2014-2016: Czech Science Foundation 14-08423S - Structure-activity-toxicity relationships studies in the group of small-molecule compounds with antimycobacterial activity
  • 2012-2015: EU project "Pre-Seed" Reg. No. CZ.1.05/3.1.00/13.0284
  • 2014-2015: EU project "Pre-Seed II" Reg. No. CZ.1.05/3.1.00/14.0299
  • 2010-2012: Charles University project 55610/2010  "Synthesis and properties of selenium analogues of sulphur antituberculotics"
  • 2010 - Ministry of education project FRVS 534/2010/F6/a
  • 2005 - 2011: Ministry of education project 1M6138896301 "Centre for new antivirals and antineoplastics"
  • 2005 - 2011: Ministry of education project MSM 0021620822 "Research of new drugs"

Synthesis of dexrazoxane analogues and iron chelators

Ongoing projects

Past (since 2010)

  • Charles University in Prague: "Centre for research of toxic and protective effects of drugs on cardiovascular system" (2012-2017)
  • Czech Science Foundation (GA ČR): 13-15008S - New potential cardioprotective agents: study of structure-activity relationships in various types of myocardial injury (2013 - 2017)
  • 2009-2012: Czech Science Foundation (Grant 305/09/0416) "Myocardial damage induced by anticancer drugs and ischemia-reperfusion : new possibilities of pharmacologicla cardioprotection"

 

 

 

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