Assoc. Prof. PharmDr. Lukáš Červený, Ph.D.

CONTACT INFORMATION:

Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 03 Hradec Králové, Czech Republic
Tel.: +420-495067292
e-mail: cervenyl@faf.cuni.cz


ORCID: 0000-0002-1313-306X
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ONGOING RESEARCH

A member of Placenta in Health and Disease Group (Faculty of Pharmacy in Hradec Králové). For detailed information, please visit our web site.

We focus on research of:

  • the role of nucleoside transporters, nucleosides, and adenosine receptors for the growth of the trophoblast layer, i.e. the barrier between maternal and fetal circulation in the placenta
  • drug-drug interactions on intestinal drug transporters and biotransformation enzymes and their effects on intestinal drug absorption with special focus on antiviral drugs

RECENT/PAST RESEARCH AREAS

  • identification of prognostic markers of disease progress in patients with resected pancreatic cancer treated with gemcitabine
  • role of ABC and SLC transporters in placental kinetics of antiviral drugs
  • identification of virulence factors in Francisella tularensis
  • nuclear receptor-mediated transcriptional regulation of ABCB1 and CYP3A4
  • interactions of antiepileptic drugs with breast cancer resistance protein
  • tryptophan and serotonin handling in the placenta; role in the fetal programming

EMPLOYMENT HISTORY

  • since 7/2019 – Assoc. Prof. at the Department of Pharmacology and Toxicology (Faculty of Pharmacy in Hradec Králové, Charles University)
  • 11/2011 – 6/2019 – Assist. Prof. at the Department of Pharmacology and Toxicology (Faculty of Pharmacy in Hradec Králové, Charles University in Prague)
  • 7/2006 - 10/2011 – Head of the group B focused on biology, Centre of Advanced Studies (Faculty of Military Health Sciences, University of Defence)
  • 2003 - 2004 - Centre for Research of Structure and Mechanism of Action of Potential New Drugs

EDUCATION

  • 2019 – Assoc. Prof. in human and veterinary pharmacology (Faculty of Pharmacy in Hradec Králové, Charles University)
  • 2008 – PharmDr. and Ph.D. degree (program: Pharmacology and Toxicology; Faculty of Pharmacy in Hradec Králové, Charles University in Prague)
  • 2003 – Master’s degree in pharmacy (program: Pharmacy; Faculty of Pharmacy in Hradec Králové, Charles University in Prague)

FOREIGN WORK EXPERIENCE

  • 2007 - Department of Medical Countermeasures, Division of NBC-Defence, Swedish Defence Research Agency (FOI), Umea (Sweden) (1 month)
  • 2006 - Department of Medical Countermeasures, Division of NBC-Defence, Swedish Defence Research Agency (FOI), Umea (Sweden) (3 months)
  • 2004 - Department of Pathophysiology, University in Vienna (Austria) (2 months)

SCIENTIFIC EXPERIENCE (2017-2021)

  • full-text papers published in jourals with IF: 19 (3x first author, 5x corresponding author)
  • supervising consultant of Ph.D. students, who have already defended the doctoral theses: 2x
  • supervisor of Ph.D. students, who defended doctoral thesis: 2x
  • current number of Ph.D. students: 3 
  • since 2011, a guarantor of a project provided by the Charles University Grant Agency (1x), a member of research teams in projects supported by the Charles University Grant Agency (>5x), a member of research teams projects granted by the Czech Science Foundation (4x, one ongoing project), a senior scientist in ongoing junior grant provided by the Czech Health Council Grant Agency
  • a reviewer of grant applications: GAUK (> 40x), Czech Health Research Council (8x)
  • a reviewer of full-text papers in journals with/without IF: e.g. Frontiers in Pharmacology, Pharmaceutical Research, Infection and Immunity, DNA and Cell Biology, Xenobiotica, Cancers, Antimicrobial Agents and Chemotherapeutics, Phytomedicine, European Journal of Obstetrics and Gynecology, PeerJ, Journal of Drug Targeting, etc.

CUMULATIVE IMPACT FACTOR (2007 – 2022):

  • > 165 (in total 42 full-text papers in SCOPUS database), average IF = 3.96

CITATIONS (11 March 2022 in Scopus database)

  • 1104 (965 without self-citations), H-index = 19 (17 without self-citations)

TEACHING EXPERIENCE

  • pharmacology seminars (96 hours/academic year)
  • pharmacology lectures (8 hours/academic year)
  • pharmacokinetics lectures (4 hours/academic year; a guarantor of this subject)
  • pharmacokinetics exercises (10 hours/academic year)
  • modern Strategy in Pharmacotherapy lectures (6 hours/academic year; aguarantor of this subject)
  • pharmacology lectures at the MBS College of Crete (14 hours/academic year)
  • dupervision of diploma theses (> 35x)
  • an author of a chapter on drug receptors in a textbook for students of Molecular pathology (University of Defence)
  • exams in Pharmacology, Pharmacokinetics, Modern Strategy in Pharmacology
  • a member of the committee for state exams of undergraduate and postgraduate students
  • a member of the committee for diploma theses defense

PROFESSIONAL MEMBERSHIP

  • Czech Society for Experimental and Clinical Pharmacology and Toxicology
  • International Society for the Study of Xenobiotics

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