PharmDr. Jana Karlíčková, Ph.D.

Education and employment

• 2002 – up till now: teaching assistant and research fellow  at the Department of Pharmaceutical Botany and Ecology, FaF UK in HK
• 2002 Ph.D.: Charles University in Prague, Faculty of Pharmacy in Hradec Králové, subject Toxicology of natural products
• 1999 – 2002: teaching assistant and research fellow at the Department of Pharmaceutical Botany and Ecology, FaF UK in HK
• 1996: master study (M.Sc. in Pharmacy) - Faculty of Pharmacy in Hradec Králové, Charles University in Prague
• 1991: graduation from the Grammar school of Jiří Orten in Kutná Hora

Research fellowship

• a short-term research fellowship at the Department of Pharmacognosy and Botany, Faculty of Pharmacy in Bratislava, Slovakia (2003)
• 3 months fellowship at the University of Sassari (Department of Natural and Land Sciences, Italy, June-September, 2017)

Membership in scientific and professional organisations

• Member of the Committee for Defence of Diploma Thesis
• Member of the Committee for the State Rigorous Exam on subject Toxicology of Natural Products
• Member of the Czech Pharmaceutical Society of J. E. Purkyně, Section of Natural Substances
• Member of the Committee for Medicinal Plants of Ministry of Health

Publications

• Currently the author of 19 publications (average IF in impacted publications: 3.0)
• ORCID No.: 0000-0002-8536-9645
• Scopus Author ID: 23568098400
• Reseacher ID: T-3474-2017

2019

• Macáková K, Catapano MC, Tvrdý V, Klimková K, Karlíčková J & Mladěnka P. Hematoxylin assay of cupric chelation can give false positive results. J Trace Elem Med Biol 52: 29-36  (2019)

2018

• Tvrdý V, Catapano MC, Rawlik T, Karlíčková J, Biedermann D, Křen V, Mladěnka P, Valentová K. Interaction of isolated silymarin flavonolignans with iron and copper. J Inorg Biochem 189: 115-123 (2018)

• Applová L, Veljovic E, Muratovic S, Karlíčková J, Macáková K, Završnik D, Saso L, Duric K, Hrdina R, Mladěnka P. 9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug antagonizing the effect of thromboxane A2, Med Chem 14(2): 200-209 (2018)
• Mladěnka P, Applová L, Patočka J, Costa VM, Remiao F, Pourová J, Mladěnka A, Karlíčková J, Jahodář L, Vopršalová M, Varner KJ & Štěrba M. TOX-OER and CARDIOTOX Hradec Králové researchers and collaborators. Comprehensive review of cardiovascular toxicity of drugs and related agents. Med Res Rev 38(4):1332-1403 (2018)
• Catapano MC, Karlíčková J, Tvrdý V, Sharma S,  Prasad AK,  Saso L,  Chhillar AK, Kuneš J,  Pour M,  Parmard, VS & Mladěnka P. Mono and Dihydroxy Coumarin Derivatives: Copper Chelation and Reduction Ability. J Trace Elem Med Biol 46, 88-95 (2018)
• Catapano MC, Tvrdý V, Karlíčková J, Mercolini L & Mladěnka P. A simple, cheap but reliable method for evaluation of zinc chelating properties. Biorg Chem 77:287-292 (2018)

2017

• Applová L., Karlíčková J., Říha M., Filipský T., Macáková K., Spilková J., Mladěnka P. The isoflavonoid tectorigenin has better antiplatelet potential than acetylsalicylic acid. Phytomedicine 35:11-7 (2017)
• Catapano MC, Tvrdý V, Karlíčková J, Migkos T, Valentová K, Křen V, Mladěnka P. The Stoichiometry of Isoquercitrin Complex with Iron or Copper Is Highly Dependent on Experimental Conditions. Nutrients 9, 1193 (2017)

2016

• Karlíčková J., Říha M., Filipský T., Macáková K., Hrdina R. & Mladěnka P. Antiplatelet effects of flavonoids mediated by inhibition of arachidonic acid based pathway. Planta Med 82(01/02):76-83 (2016)

2015

• Filipský T., Říha M., Macáková K., Anzenbacherová E., Karlíčková J. & Mladěnka P.: Antioxidant Effects of Coumarins Include Direct Radical Scavenging, Metal Chelation and Inhibition of Ros-Producing Enzymes. Curr Top Med Chem 15(5): 415-31 (2015)
• Karlíčková J., Macáková K., Říha M., Pinheiro L.M.T., Filipský T., Horňasová V., Hrdina R. & Mladěnka P. Isoflavones Reduce Copper with Minimal Impact on Iron In Vitro. Oxid Med Cell Longev (2015): 2015; 2015: article ID 437381 

2014

• Říha M., Karlíčková J., Filipský T., Macáková K., Rocha L., Bovicelli P., Proietti Silvestri I., Saso L., Jahodář L., Hrdina R. & Mladěnka P.: In vitro evaluation of copper-chelating properties of flavonoids. RSC Advances 4 (62): 32628 - 32638 (2014)

< 2013

• Říha M., Karlíčková J., Filipský T., Macáková K., Hrdina R. & Mladěnka P.: Novel method for rapid copper chelation assessment confirmed low affinity of D-penicillamine for copper in comparison with trientine and 8-hydroxyquinolines. Journal of Inorganic Biochemistry 123, 80-87 (2013)
• Macáková K., Řeháková Z., Mladěnka P., Karlíčková J., Filipský T., Říha M., Prasad A. D., Parmar V. S., Jahodář L., Pávek P., Hrdina R., Saso L.: In vitro platelet antiaggregatory properties of 4-methylcoumarins. Biochimie; 94(12), 2681-6 (2012)
• Řeháková Z., Karlíčková J., Jahodář L.: Sunflower (Helianthus annuus L.) – substances and their biological activity, Chemické listy 102, 116 – 123 (2008)
• Karlíčková J.: Expektorancia přírodního původu – díl druhý, Praktické lékárenství 4 (5), 238-240 (2008)
• Karlíčková J.: Terapeutické účinky Salvia officinalis, Praktické lékárenství 3 (1), 33-34 (2007)
• Karlíčková J.: Nové poznatky o účincích Rhodococcum vitis-idaea, Praktické lékárenství 3 (6), 296-298 (2007)
• Klečáková – Karlíčková J., Jahodář L.: Xanthium spinosum L. – a phytochemical study, Česká a slovenská farmacie 54 (3), 141-144 (2005)
• Klečáková J., Chobot V., Jahodář L., Laakso I., Víchová P.: Antiradical activity of petals of Philadelphus coronarius L., Central European Journal of Public Health 12 (Supplement), S39-S40 (2004)
• Jahodář L., Klečáková J.: Toxicita hvězdnicovitých s přihlédnutím k farmaceuticky významným druhům, Chemické listy 93, 320-326 (1999)
• Klečáková J., Jahodář L.: Adverse and toxic effects of plants, Folia pharmaceutica XXIV, 55-78 (1999)
• Lamka J., Vondřejc M., Klečáková J.: Efficacy of flubendazole against Muellerius capillaris in mouflon. Veterinární medicína 41 (11), 347 – 350 (1996)