Assoc. Prof. Ing. Petra Matoušková, Ph.D.

Current position


  • 2003-2008 Postgraduate Studies leading to a Ph.D. degree in Microbiology (Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague)
  • 1998-2003 Biomedical Engineering (Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague)

Work experience

  • 2019 Research associate – Assoc. Prof. in Biochemistry
  • 2015-2019 Research assistant in the Department of Biochemical Sciences, Faculty of Pharmacy, Charles University
  • 2012-2014 Postdoctoral position in the Department of Biochemical Sciences, Faculty of Pharmacy, Charles University (Postdoci na UK)
  • 2012 Postdoctoral research stay in Max Planck Institute for Chemical Ecology, Jena, Germany (6 months)
  • 2010-2012 Maternity leave
  • 2008-2009 Postdoctoral position at the University of Exeter, School of Biosciences, Exeter, UK (14 months)
  • 2002-2008 Institute of Organic Chemistry and Biochemistry AS CR, Prague (research assistant as a postgraduate student in the laboratory of Biochemistry)
  • 2005-2006 DAAD fellowship: D32-CZ21/05-05 Exchange program in Max Planck Institute of Chemical Ecology, Jena, Germany (two 2-months stays as a postgraduate student)

Research interest

  • expression, function and post-transcriptional regulation of drug metabolizing and antioxidant enzymes  
  • bioinformatics - database search, alignments, phylogenetics, python scripting
  • epigenetics – microRNA interactions, DNA methylation
  • ecotoxicology


  • Introduction to applied bioinformatics
  • Xenobiochemistry
  • Practical classes in molecular biology

Grants Received

  • 2018-2020 Charles University (PRIMUS/17/SCI/4: miRNA role in the drug resistance of nematodes)
  • 2017-2019 Czech Science Foundation (17-95411Y: UDP-glycosyltransferases in Haemonchus contortus –players in drug-resistance?)
  • 2016 Internal Research project (Inclusion of new subject: Introduction to Applied Bioinformatics)

Other scientific achievements

  • 2020-2021 FaF coordinator: Erasmus+ project “Bioinformatics centre Hradec Králové” KA203-7BA9D4F2
  • 2016 Patent application: Kunke D., Matoušková P. iPSCs PCR array card - UKLFHK-160518

Other notable information

  • 2019 - present Czech Society for Parasitology membership
  • 2019 Medal of the dean of the Faculty of Pharmacy for the scientific contribution
  • 2021 Member of organising committee of 26th Helminthological Days

Summary of publication activity

> 50 papers in international peer-reviewed journals (sum of IF > 180), 684 times cited (Scopus),
h-index: 14

Publications over the last three years:

  • Dimunová D., Matoušková P., Navrátilová M., ...Szotáková B., Skálová L. Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus. (2022) Science of the Total Environment 822, 153527
  • Zajíčková M., Prchal L., Navrátilová M., Matoušková P., ...Nguyen L.T., Skálová L. Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation. (2021) Veterinary Research 52(1), pp. 143
  • Hanousková B., Vávrová G., Ambrož M., ...Skálová L., Matoušková P*. MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis. (2021) Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1864(10), 194734.          
  • Navrátilová M., Raisová Stuchlíková L., Matoušková P., ...Szotáková B., Skálová L. Proof of the environmental circulation of veterinary drug albendazole in real farm conditions. (2021) Environmental Pollution 286, 117590.                                                                                                             
  • Nguyen L.T., Zajíčková M., Mašátová E., Matoušková P., Skálová L. The ATP bioluminescence assay: a new application and optimization for viability testing in the parasitic nematode Haemonchus contortus. (2021) Veterinary Research 52(1), 124.                                                              
  • Kellerová P., Navrátilová M., Nguyen L.T., ...Skálová L., Matoušková P. UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus. (2020) Frontiers in Physiology 11, 594116.                                                                              
  • Kellerová P., Raisová Stuchlíková L., Matoušková P., ...Szotáková B., Skálová L. Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults.  (2020) Veterinary Research 51(1), 94.   
  • Zajíčková M., Nguyen L.T., Skálová L., Raisová Stuchlíková L., Matoušková P*. Anthelmintics in the future: current trends in the discovery and development of new drugs against gastrointestinal nematodes. (2020) Drug Discovery Today 25(2), pp. 430–437.                     


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