Assoc. Prof. PharmDr. Hana Sklenářová, Ph.D.

Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University
deputy head of the department and associate professor
member of Analytical Chemistry Group
Contacts:
- E-mail: Hana.Sklenarova@faf.cuni.cz
- Address: Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
- Phone: +420 495 067 453
- Fax: +420 495 067 164
ORCID ID: 0000-0003-1700-7447
Research ID: S-5533-2017
Scopus Author ID: 6603434004

Education and Employment

2018 – senior member of EFSA-CDN project (Efficiency and safety improvement of current drugs and nutraceuticals: advanced methods – new challenge)
2017 – senior member of STARSS project (Specialized Team for Advanced Research on Separation Science)
2017 – head of the doctoral study committee - Pharmaceutical Analysis
2012 – habilitation in Analytical chemistry; Thesis: Automation of extraction techniques using non-separation flow methods, Habilitation lecture: Automation in analytical chemistry
2011 – deputy head of the Department of Analytical Chemistry
2002 – senior lecturer at the Department of Analytical Chemistry
2001 – Ph.D.: Drug control, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Thesis: Application of automated flow methods in pharmaceutical analysis
2001 – rigorosis procedure, obtaining PharmDr. degree, Drug control, Faculty of Pharmacy in Hradec Králové, Charles University in Prague
2000 – junior lecturer at the Department of Analytical Chemistry
1997 – graduation from Pharmacy, obtaining Mgr. degree, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Thesis: Chromatographic separation of betaines

2016 (November, one week) - University of Balearic Islands, Palma de Mallorca, Spain.
2015 (November, two weeks) - University of Hawaii at Manoa, Honolulu, USA.
2014 (March, one week) - University of Balearic Islands, Palma de Mallorca, Spain.
2013 (September, one week) - University of Porto, Porto, Portugal.
2010 (October, one week) – University of P. J. Šafárik, Košice, Slovakia.
2008 (September, one week) – University of Bologna, Bologna, Italy.
2003 (May, one week) – University of Porto, Porto, Portugal.
2001 (March, one week) – University of Balearic Islands, Palma de Mallorca, Spain.
1999 (February, one month) – University of Graz, Austria.
1999 (September, 4 months) – University of Porto, Porto, Portugal.

Non-separation flow methods (Flow injection analysis (FIA), sequential injection analysis (SIA))
Spectrophotometric, fluorimetric, chemiluminescence detections in flow systems
Dissolution and liberation studies of pharmaceutical formulations with normal and prolonged liberation, monitoring of long-term processes
Permeation tests - automation of long-term monitoring of the interaction of biologically active substances with membrane transporters
Automation of drinking and surface water analysis – transfer of ISO procedures to the flow system
Development of sample preparation techniques – automation of extraction procedures (L-L extraction, dispersive L-L micro-extraction) using non-separation flow methods (DV-SIA – dual-valve sequential injection analysis), solid phase extraction in cartridge and bead injection formats
Sequential injection chromatography (SIC) – application of analysis of composed pharmaceutical formulations, gradient elution
Liquid chromatography (HPLC) – development of separation methods for determination, purity control and stability tests of chemical drugs in commercially available pharmaceutical formulations, determination of drugs in toxicological studies, determination of anti-oxidants in plant material

Analytical chemistry (+ e-learning)
Instrumental methods (+ e-learning)
Special methods of instrumental analysis (lectures and practical course + e-learning)
Special instrumental methods
Food analysis
Calculations in analytical chemistry
Evaluation in instrumental methods
Supervisor of bachelor, diploma, rigorosis and Ph.D. projects
Guarrantor of specialization Pharmaceutical Analysis

2017 – 2019 – Technology Agency of the Czech Republic - project Zeta - Monitoring of compounds with benefits in fruits and its processed products with respect to the human health and children nutrition
2014 – 2015 – Ministry of Education – bilateral cooperation with Argentina (Mobility project), Application of modern flow methodologies for determination of biologically active compounds in complex matrices
2012 – 2013 – Ministry of Education – bilateral cooperation with Argentina (Mobility project), Application of flow analytical methods for water quality monitoring
2011 – Ministry of Education – Innovation of subject Instrumental methods following pharmacopoeial legislation
2009 – Ministry of Education – Introduction of new practical task determination of quinine using sequential injection analysis in drinks included to Food analysis subject
2005 – Charles University – Automation of liberation tests of topical pharmaceutical formulation using Franz cell in the SIA system
2002 – Czech Science Foundation – Automation of dissolution tests using Sequential injection analysis (post-doc project)
2000 – Ministry of Education – Development of universal control program for automated flow analysis