Assoc. Prof. PharmDr. Hana Sklenářová, Ph.D.

Education and Employment

• 2018 – senior member of EFSA-CDN project (Efficiency and safety improvement of current drugs and nutraceuticals: advanced methods – new challenge)
• 2017 – senior member of STARSS project (Specialized Team for Advanced Research on Separation Science)
• 2017 – head of the doctoral study committee - Pharmaceutical Analysis
• 2012 – habilitation in Analytical chemistry; Thesis: Automation of extraction techniques using non-separation flow methods, Habilitation lecture: Automation in analytical chemistry
• 2011 – deputy head of the Department of Analytical Chemistry
• 2002 – senior lecturer at the Department of Analytical Chemistry
• 2001 – Ph.D.: Drug control, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Thesis: Application of automated flow methods in pharmaceutical analysis
• 2001 – rigorosis procedure, obtaining PharmDr. degree, Drug control, Faculty of Pharmacy in Hradec Králové, Charles University in Prague
• 2000 – junior lecturer at the Department of Analytical Chemistry
• 1997 – graduation from Pharmacy, obtaining Mgr. degree, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Thesis: Chromatographic separation of betaines

Research fellowships

• 2016 (November, one week) - University of Balearic Islands, Palma de Mallorca, Spain.
• 2015 (November, two weeks) - University of Hawaii at Manoa, Honolulu, USA.
• 2014 (March, one week) - University of Balearic Islands, Palma de Mallorca, Spain.
• 2013 (September, one week) - University of Porto, Porto, Portugal.
• 2010 (October, one week) – University of P. J. Šafárik, Košice, Slovakia.
• 2008 (September, one week) – University of Bologna, Bologna, Italy.
• 2003 (May, one week) – University of Porto, Porto, Portugal.
• 2001 (March, one week) – University of Balearic Islands, Palma de Mallorca, Spain.
• 1999 (February, one month) – University of Graz, Austria.
• 1999 (September, 4 months) – University of Porto, Porto, Portugal.

Research Interests

• Non-separation flow methods (Flow injection analysis (FIA), sequential injection analysis (SIA))
• Spectrophotometric, fluorimetric, chemiluminescence detections in flow systems
• Dissolution and liberation studies of pharmaceutical formulations with normal and prolonged liberation, monitoring of long-term processes
• Permeation tests - automation of long-term monitoring of the interaction of biologically active substances with membrane transporters
• Automation of drinking and surface water analysis – transfer of ISO procedures to the flow system
• Development of sample preparation techniques – automation of extraction procedures (L-L extraction, dispersive L-L micro-extraction) using non-separation flow methods (DV-SIA – dual-valve sequential injection analysis), solid phase extraction in cartridge and bead injection formats
• Sequential injection chromatography (SIC) – application of analysis of composed pharmaceutical formulations, gradient elution
• Liquid chromatography (HPLC) – development of separation methods for determination, purity control and stability tests of chemical drugs in commercially available pharmaceutical formulations, determination of drugs in toxicological studies, determination of anti-oxidants in plant material

Teaching

• Analytical chemistry (+ e-learning)
• Instrumental methods (+ e-learning)
• Special methods of instrumental analysis (lectures and practical course + e-learning)
• Special instrumental methods
• Food analysis
• Calculations in analytical chemistry
• Evaluation in instrumental methods
• Supervisor of bachelor, diploma, rigorosis and Ph.D. projects
• Guarrantor of specialization Pharmaceutical Analysis

Professional Membership

• Member of Editorial board of Journal of Analytical Methods in Chemistry

Grants Received

• 2017 – 2019 – Technology Agency of the Czech Republic - project Zeta - Monitoring of compounds with benefits in fruits and its processed products with respect to the human health and children nutrition
• 2014 – 2015 – Ministry of Education – bilateral cooperation with Argentina (Mobility project), Application of modern flow methodologies for determination of biologically active compounds in complex matrices
• 2012 – 2013 – Ministry of Education – bilateral cooperation with Argentina (Mobility project), Application of flow analytical methods for water quality monitoring
• 2011 – Ministry of Education – Innovation of subject Instrumental methods following pharmacopoeial legislation
• 2009 – Ministry of Education – Introduction of new practical task determination of quinine using sequential injection analysis in drinks included to Food analysis subject
• 2005 – Charles University – Automation of liberation tests of topical pharmaceutical formulation using Franz cell in the SIA system
• 2002 – Czech Science Foundation – Automation of dissolution tests using Sequential injection analysis (post-doc project)
• 2000 – Ministry of Education – Development of universal control program for automated flow analysis

Awards/Prizes

• 1998 – one-year scholarship of the Josef Hlávka Foundation
• 1996 – award of Josef Hlávka Foundation