PharmDr. Eva Šnejdrová, Ph.D.

Contact Information     

     E-mail: snejdrova@faf.cuni.cz
     Tel.: +420 495 067 399

ORCID ID: https://orcid.org/0000-0001-8788-5603
Researcher ID: T-1821-2017
Scopus Author ID: 6507465444

Teaching activities

Research interests

  • Synthesis, characterization, and degradation studies of PLGA-based polyesters of branched architecture
  • Formulation and characterization of drug loaded biodegradable micro and nanoparticles (Malvern Mastersizer 3000, Zetasizer nano ZS Malvern - particle size, PDI, zeta-potential; encapsulation efficiency; dissolution testing)
  • Formulation and testing of PLGA based implantable DDS of the ISFI type, solid dispersions and thin layers (melting method, solvent method, plasticization)
  • Rheological behaviour of coating dispersions, polymers, pharmaceutical semisolid excipients and preparations, plasticized polyesters (absolute rheometer Kinexus Pro+ Malvern - rotational, oscillation and creep tests)
  • Dissolution testing (USP 1, 2, 4)
  • In vitro testing of mucoadhesion by tensile tests (rheometer Kinexus Pro+Malvern, material testing machine Zwick/Roell), and "wash out" tests
  • Thermal analysis of drugs, pharmaceutical excipients, polymeric systems (DSC 200 F3 Maia Netzsch)

Collaboration

Industry

  • Teva Czech Industries s.r.o.
  • Zentiva Group, a.s.
  • ​Dr. Müller Pharma s.r.o. 
  • Contipro a.s.

Academic sphere

  • Belgorod State National Research University, Russion Union
  • University of Szeged, Institute of Pharmaceutical Technology and Regulatory Affairs, Hungary
  • Faculty of Pharmacy, Jagiellonian University, Poland
  • MBS College of Crete, Greece

Publications

Snejdrova, E., Podzimek, S., Martiska, J., Holas, O., Dittrich, M. (2020) Branched PLGA derivatives with tailored properties for drug delivery, Acta Pharmaceutica, https://doi.org/10.2478/acph-2019-0031, https://content.sciendo.com/view/journals/acph/70/1/article-p63.xml

Juraj Martiska, Eva Snejdrova, Martin Drastik, Ludmila Matysova, Milan Dittrich, Jan Loskot & Petr Jilek (2019): Terbinafine-loaded branched PLGA-based cationic nanoparticles with modifiable properties, Pharmaceutical Development and Technology, DOI: 10.1080/10837450.2019.1667387, https://www.tandfonline.com/doi/full/10.1080/10837450.2019.1667387

Siska, B., Snejdrova, E., Machac, I., Dolecek, P., Martiska, J.  (2019) Contribution to the rheological testing of pharmaceutical semisolids, Pharmaceutical Development and Technology, 24:1, 80-88, https://doi.org/10.1080/10837450.2018.1425432

Snejdrova, E., Drastik, M., Dittrich, M., Kastner, P., Nguyenova, J. (2016) Mucoadhesive plasticized system of branched poly(lactic-co-glycolic acid) with aciclovir, Drug Development and Industrial Pharmacy, 42:10, 1653-1659, http://dx.doi.org/10.3109/03639045.2016.1160109

Dittrich, M., Snejdrova, E. (2014) Cyclic Swelling as a Phenomenon Inherent to Biodegradable Polyesters. J. Pharm. Sci. 103, 3560-3566, http://onlinelibrary.wiley.com/doi/10.1002/jps.24146/full

Snejdrova, E., Drastik, M., Dittrich, M. (2013) Plasticized branched aliphatic oligoesters as potential mucoadhesive drug carriers. Int. J. Pharm., 458, 282– 286 http://dx.doi.org/10.1016/j.ijpharm.2013.10.030

Snejdrova, E., Dittrich, M. Pharmaceutically used plasticizers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 45-68. ISBN 978-953-51-0363-9. DOI: 10.5772/39190
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutically-used-plasticizers-

Snejdrova, E., Dittrich, M. Pharmaceutical applications of Plasticized Polymers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 69-90. ISBN 978-953-51-0363-9. DOI: 10.5772/36543
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutical-applications-of-plasticized-polymers

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