PharmDr. Eva Šnejdrová, Ph.D.

Teaching activities

• Pharmaceutical Technology I and II
• Physical Principles of Dosage Forms
• Selected Methods of Pharmaceutical Technology
• Mentor of more than 60 defended diploma thesis
• Consultant of more than 30 rigorous thesis

Research interests

• Synthesis, characterization, and degradation studies of PLGA-based polyesters of branched architecture
• Formulation and characterization of drug loaded biodegradable micro and nanoparticles (Malvern Mastersizer 3000, Zetasizer nano ZS Malvern - particle size, PDI, zeta-potential; encapsulation efficiency; dissolution testing)
• Formulation and testing of PLGA based implantable DDS of the ISFI type, solid dispersions and thin layers (melting method, solvent method, plasticization)
• Rheological behaviour of coating dispersions, polymers, pharmaceutical semisolid excipients and preparations, plasticized polyesters (absolute rheometer Kinexus Pro⁺ Malvern - rotational, oscillation and creep tests)
• Dissolution testing (USP 1, 2, 4)
• In vitro testing of mucoadhesion by tensile tests (rheometer Kinexus Pro⁺Malvern, material testing machine Zwick/Roell), and "wash out" tests
• Thermal analysis of drugs, pharmaceutical excipients, polymeric systems (DSC 200 F3 Maia Netzsch)

Collaboration

Industry

• Teva Czech Industries s.r.o.
• Zentiva Group, a.s.
• ​Dr. Müller Pharma s.r.o. 
• Contipro a.s.

Academic sphere

• Belgorod State National Research University, Russion Union
• University of Szeged, Institute of Pharmaceutical Technology and Regulatory Affairs, Hungary
• Faculty of Pharmacy, Jagiellonian University, Poland
• MBS College of Crete, Greece

Publications

Muzikova, J.; Snejdrova, E.; Martiska, J.; Doubkova, B.; Veris, A. A Study of Compressibility, Compactability and Mucoadhesivity of Tableting Materials for Matrix Systems Based on Chitosan. Polymers 2021, 13, 3636. IF 4.329 Q1 https://doi.org/10.3390/polym13213636

Snejdrova, E., Martiska, J., Loskot, J., Paraskevopoulos, G., Kovacik, A., Regdon JR., G., Budai-Szucs, M., Palat, K., Konecna, K. PLGA based film forming systems for superficial fungal infections treatment, Eur. J. Pharm. Sci. 2021, 136, 13p. Q2, IF₂₀₂₀ 4.384, ISSN 0928-0987 https://doi.org/10.1016/j.ejps.2021.105855

Snejdrova, E., Podzimek, S., Martiska, J., Holas, O., Dittrich, M. (2020) Branched PLGA derivatives with tailored properties for drug delivery, Acta Pharmaceutica, https://doi.org/10.2478/acph-2019-0031, https://content.sciendo.com/view/journals/acph/70/1/article-p63.xml

Martiska, J., Snejdrova, E., Drastik, M., Matysova, L., Dittrich, M., Loskot, J., Jilek, P. Terbinafine-loaded branched PLGA-based cationic nanoparticles with modifiable properties, Pharmaceutical Development and Technology 2019, 24, 10, 1308-1316 DOI: 10.1080/10837450.2019.1667387, https://www.tandfonline.com/doi/full/10.1080/10837450.2019.1667387

Siska, B., Snejdrova, E., Machac, I., Dolecek, P., Martiska, J.  (2019) Contribution to the rheological testing of pharmaceutical semisolids, Pharmaceutical Development and Technology, 24:1, 80-88, https://doi.org/10.1080/10837450.2018.1425432

Snejdrova, E., Drastik, M., Dittrich, M., Kastner, P., Nguyenova, J. (2016) Mucoadhesive plasticized system of branched poly(lactic-co-glycolic acid) with aciclovir, Drug Development and Industrial Pharmacy, 42:10, 1653-1659, http://dx.doi.org/10.3109/03639045.2016.1160109

Dittrich, M., Snejdrova, E. (2014) Cyclic Swelling as a Phenomenon Inherent to Biodegradable Polyesters. J. Pharm. Sci. 103, 3560-3566, http://onlinelibrary.wiley.com/doi/10.1002/jps.24146/full

Snejdrova, E., Drastik, M., Dittrich, M. (2013) Plasticized branched aliphatic oligoesters as potential mucoadhesive drug carriers. Int. J. Pharm., 458, 282– 286 http://dx.doi.org/10.1016/j.ijpharm.2013.10.030

Snejdrova, E., Dittrich, M. Pharmaceutically used plasticizers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 45-68. ISBN 978-953-51-0363-9. DOI: 10.5772/39190
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutically-used-plasticizers-

Snejdrova, E., Dittrich, M. Pharmaceutical applications of Plasticized Polymers. In: Recent Advances in Plasticizers. M. LUQMAN (ed.), 2012, 69-90. ISBN 978-953-51-0363-9. DOI: 10.5772/36543
https://www.intechopen.com/books/recent-advances-in-plasticizers/pharmaceutical-applications-of-plasticized-polymers