Mgr. Nela Váňová

Date and Place of Birth:
29th March 1989, Kolin, Czech Republic

Present position:
Assistant at Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Kralove, Charles University; member of Pharmaceutical Analysis Group

Contact information:
Faculty of Pharmacy in Hradec Kralove, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic
Tel. +420 495067238
E-mail: vanovan@faf.cuni.cz

ORCID iD: orcid.org/0000-0002-1827-9308

Research focus:

  • Separation techniques (HPLC/LC-MS/MS)
  • Development of analytical and bioanalytical methods for the determination of toxic and pharmaceutically active compounds
  • Oxidative stress biomarkers

Education:

  • Since 2013
    Ph.D. study in Toxicology - Faculty of Military Health Sciences in Hradec Kralove, University of Defence (Thesis: Determination of oxidative stress biomarkers by HPLC; supervisor: Assoc. Prof. PharmDr. Daniel Jun, Ph.D.)
  • 2008 – 2013
    Mgr. (equiv. MS.c.) in Pharmacy - Faculty of Pharmacy in Hradec Kralove, Charles University (Diploma Thesis: Analysis of oxidative and free radical induced DNA damage; supervisor: Assoc. Prof. PharmDr. Radim Kucera, Ph.D.)

Professional carrier:

  • Since 2018
    Assistant at Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Kralove, Charles University
  • 2017 – 2018
    Assistant at Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence
  • Since 2013
    Researcher at Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences in Hradec Kralove, University of Defence

Educational activities:

  • Since 2018 Tutor of practical training from Pharmaceutical Analysis
  • Since 2018 Consultant of Diploma Theses at Faculty of Pharmacy in Hradec Kralove
  • Since 2017 Supervisor of Student research projects at Faculty of Military Health Sciences in Hradec Kralove, University of Defence  

Grant projects:

  • Since 2018     
    SV/FVZ201807 – Determination of toxicological parameters and markers of exposure to potential chemical warfare agents (co-investigator)
  • 2015 – 2017   
    SV/FVZ201505 – Determination of selected chemical warfare agents and toxins in complex biological matrices using chromatography methods (co-investigator)
  • 2014-2016     
    SV/FVZ2018 – Development of LC-MS methods for determination of oxidative stress biomarkers for evaluation of toxicity of new potential drugs (principal investigator)

International projects:

  • Since 2015     
    Organization for the prohibition of chemical weapons (OPCW, Haag, Netherlands) – Official OPCW Biomedical Proficiency Tests on the determination of markers of exposure to chemical warfare agents

Research fellowship:

  • 2012 – 2013   
    National Research Council, Institute of Organic Synthesis and Photoreactivity  (Bologna, Italy) - Analysis of oxidative and free radical induced DNA damage – Dr. Carla Ferreri (5 months)

Publications:

Journals with impact factor (∑IF = 6.128; ØIF = 2.043)

VANOVA, Nela, Jaroslav PEJCHAL, David HERMAN, Alzbeta DLABKOVA and Daniel JUN. Oxidative stress in organophosphate poisoning: role of standard antidotal therapy. Journal of Applied Toxicology. 2018, 38(8), 1058-1070. (IF2018=2.909)

MUCKOVA, Lubica, Jaroslav PEJCHAL, Petr JOST, Nela VANOVA, David HERMAN and Daniel JUN. Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure. Drug and Chemical Toxicology. 2018, 1-5.  (IF2017=1.531)

VANOVA, Nela, Lubica MUCKOVA, Monika SCHMIDT, David HERMAN, Alzbeta DLABKOVA, Jaroslav PEJCHAL and Daniel JUN. Simultaneous determination of malondialdehyde and 3-nitrotyrosine in cultured human hepatoma cells by liquid chromatography-mass spectrometry. Biomedical Chromatography. 2018, 32(12), e4349. (IF2018=1.688)

© Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
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