Pharmaceutical Analysis Group



The research focus is on the whole area of pharmaceutical analysis and closely corresponds to the current WHO requirements for quality assurance, safety and efficacy of pharmaceuticals. The main focus is on analytical and bioanalytical studies related to the research and development of new drugs.

In this area, particular attention is paid to the development and validation of methods for the analytical evaluation of new active substances and medicinal products. In the field of bioanalytical studies, the attention is paid to the development of new achiral and chiral approaches for the determination of potential drugs and their metabolites in different biological matrices. The development of these methods has a direct link to the study of the effects of these substances on the organism, which is being carried out in the framework of preclinical studies at collaborating institutes. Different separation techniques (HPLC, UHPLC, GC and CE) in combination with different detection techniques (in particular MS, UV and fluorescence) are used for the analysis.

      The main areas of interest are:

  • Development of modern, highly sensitive bioanalytical methods for the de-Logo_Final.jpg
    termination of drugs, potential drugs, metabolites and endogenous substances in relevant biological material and application of the methods to interdisciplinary studies of their fate in the organism.
  • Chiral separation
  • Miniaturized sample preparation techniques prior to chromatographic analysis
  • Development of analytical methods for the study of oxidative stress markers
  • Evaluation of the purity and stability of drugs, excipients and pharmaceuticals using rapid separation methods 

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