Prof. RNDr. Jarmila Vinšová, Ph.D.

Head of Development of new potential drugs with antimicrobial activity research group

Address: Department of Inorganic and Organic Chemistry,
Charles University in Prague, Faculty of Pharmacy in Hradec Králové,
Heyrovského 1203, CZ- 50005 Hradec Králové, the Czech Republic

Tel: 495067343, Fax: 495067166

ORCID 0000-0002-3272-1158, Scopus Author ID: 6701677200, H index 29

Education and Degrees

  • 2011 - Professor of Pharmaceutical Chemistry at the University of Veterinary and  Pharmaceutical Sciences Brno
  • 1997 - Associate Professor of Bioorganic Chemistry - Thesis - Relationships between chemical structure and biological activity of some heterocyclic compounds. Faculty of Pharmacy in Hradec Králové, Charles University in Prague
  • 1985 - Ph.D. Thesis - Synthesis of sulphur-containing derivatives of some pyridine carboxylic acids as potential antituberculotics, Faculty of Pharmacy in Hradec Králové, Charles University in Prague
  • 1976 - RNDr. (MSc. equivalent) - Thesis - Synthesis of potential antituberculotics and antimycotics from the group of sulphur-containing pyridine derivatives. Faculty of  Pharmacy in Hradec Králové, Charles University in Prague
  • 1969-74 - Faculty of Pharmacy in Hradec Králové, Charles University in Prague 

Teaching activity

  • Guarantor of study program of Pharmacy (since 2004)
  • Senior Advisor for foreign students (since 1994)
  • ERASMUS students co-coordinator (since 1998)
  • Lecturer and guarantor of the subjects:
    • Organic Chemistry I and II, Bioorganic Chemsitry for Pharmacy in Czech and English language, Exercises in Organic Chemistry
    • Constitution of Organic Compounds for foreigner students.
  • Lecturer and guarantor of the subject Organic Chemistry for Healthcare bioanalytics - daily and distant study.
  • Supervisor of 9 Ph.D. students (7 graduated), 39 diploma-students, and 13 ERASMUS students from abroad.

Membership of the scientific societies and scientific boards

  • Member of the Scientific Council, Charles University in Prague, Faculty of Pharmacy in Hradec Králové (since 2014)
  • Czech Chemical Society (since 1976), vice-president (2010-2013)
  • Czech Pharmaceutical Society of J.E.Purkyně (since 2003)
  • Member of scientific board of Joint Meeting on Medicinal Chemistry (since 2009)
  • Head of the scientific board for PharmDr (since 2006)
  • Member of scientific board for the Ph.D. in Bioorganic Chemistry at the Faculty of Pharmacy
  • Member of scientific board for the Ph.D. in Organic Chemistry at the Institute of Chemical Technology Prague (since 2011)
  • Coordinator of Paul Ehrlich MedChem Euro-Ph.D. network at the Faculty of Pharmacy in Hradec Králové, Charles University in Prague (since 2010)


Profesional and research activity

Design and synthesis of new compounds with antimicrobial activities, especially antimycobacterial and antifungal activity. Relationships between chemical structure and biological activity, prodrug modelling of new agents active against MDR TB. Study of oxidative deamination of amino acids and peptides by using di-tert-butylbenzoquinone as pyridoxal mimics. Modelling of biological active peptides and depsipetides.

Author of 135 original papers (121 in WOS), 5 patents, 6 university textbooks, 232 posters/lectures on symposia, principal or co-investigator of 31 grant projects (4 bilateral projects, 5 European). 

Scientific grants (principal investigator)

  • 2012-2015 - Ministry of Health IGA NT 13346: Design and enzyme targeting of antibacterial active compounds against multidrug resistant strains
  • 2010-2011 - Bilateral project Kontakt Czech Republic - Slovenia: Development of novel antituberculosis agents and prodrugs effective against multidrug resistant tuberculosis
  • 2009-2011 - Ministry of Health IGA NS 10367-3: Evaluation and development of new perspective antimycobacterial drugs and prodrugs active against multidrug resistant strains.
  • 2008-2009 - Bilateral project Kontakt Czech Republic - Slovenia: Synthesis of New Antibacterial Active Compounds.
  • 2006-2009 - Ministry of Education - Development project: Increasing levels of teaching in English for teachers at the Faculty of Pharmacy Charles University
  • 2006-2007 - Bilateral project Kontakt Czech Republic – Slovenia: New approach to antibacterial active molecules.
  • 2003 - FRVŠ G4/2994: Student research activities in the field of potential antituberculotics
  • 2002 - FRVŠ G4/2261: The scientific work of students in the field of peptide chemistry and depsipeptides
  • 2001-2003 - GAČR 203/01/042: Oxidative deamination of peptides – a new approach to  depsipeptide synthesis
  • 1998-2000 - GAUK 24/1998BCH/FaF: Modelling of biologically active depsipeptides
  • 1998 - FRVŠ PG 98385: XVth EFMC International Symposium on Medicinal Chemistry - Expanding of research and development - presentation
  • 1995-1997 - GAČR 203/95/1483: Relations between chemical structure and biological activity in the group of short peptides and depsipeptides
  • 1993-1995 - GAUK 55/1995: Modelling of biologically active spirocyclic
  • 1993 - FRVŠ 0032 2: Modelling of biologically active cyclic dipeptides

European Grants (Co-Investigator)

  • TEAB - European project (CZ.1.07/2.3.00/20.0235)
  • FAFIS - European project (CZ.1.07/2.2.00/28.0194)
  • Postdoc I (CZ.1.07/2.3.00/30.0022)
  • Postdoc II UK ECOP (CZ.1.07/2.3.00/30.0061)
  • Pre-seed II UK (CZ.1.05/3.1.00/14.0299)


  • Kutschy P., Vinšová J., Berkeš D., Török M.: Základy farmaceutickej Chémie. Košice 2004, ISBN 80-7097-544-X
  • Hrabálek A., Klimešová V., Kuneš J., Palát K., Pour M., Waisser K., Vinšová J.: Soubor otázek k přijímacím zkouškám na Farmaceutickou fakultu v Hradci Králové z Chemie. Hradec Králové 2001, ISBN 80-238-6793-S
  • Hrabálek A., Kubicová L., Kuneš J., Pour M., Vinšová J.: Laboratorní cvičení z organické chemie pro farmaceuty, Karolinum Praha 1999
  • Hrabálek A., Kuneš J., Klimešová V., Macháček M., Opletal L., Palát K., Roman M., Vinšová J.: Chemická laboratorní technika pro farmaceuty. Karolinum Praha 1997
  • Vinšová J.: Laboratory manual for organic chemistry. Charles University, Karolinum Praha 1995
  • Čeladník M., Waisser K., Vinšová J., Hrabálek A.: Laboratorní cvičení z organické chemie. SPN Praha, 1990


book-development-new-mdr-tuberculosis.jpgVinšová J., Krátký M.: Development of New MDR-Tuberculosis Drugs. Nova Biomedical. New York 2010. ISBN 978-1-6168-233-0 (100 pages)


book-drug-resistant-tubersulosis.jpgVinšová J., Krátký M.: Drug-Resistant Tuberculosis: Causes, Diagnosis and Treatments (Editors: Shui Ngụy and Zhou K'ung) (Chapter 2 - Tuberculosis — The Development of New MDR-TB Drugs). Nova Biomedical, New York, 2009, ISBN 978-1-60876-055-8.

book-antioxidant-polymers.jpgJ. Vinšová, E. Vavříková: Antioxidant Polymers by Chitosan Modification (chapter in book: Antioxidant polymers, Synthesis, Properties and Applications, Editors: G. Cirillo and F. Iemma). Wiley, Sp Scrivener, 2012, page 115-151, ISBN 978-1-118-20854-0.


Publications (since 2005)


  • Houngbedji N.H., Štěpánková Š., Pflégr V., Svrčková K., Švarcová M., Vinšová J., Krátký M. Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study. Pharmaceuticals 2023, 16, 172. [ISSN 1424-8247, IF2020= 5.863] Q1,
  • Al-Otaibi J.S., Mary Y.S.; Mary Y.S., Krátký M., Vinsova J., Gamberini M.C. SERS spectroscopy for the therapeutic N-butyl-2-isonicotinoylhydrazine-1-carboxamide in silver nanocolloids at different concentrations: Experimental and DFT investigations. Journal of Molecular Structure 2023, 134905 [ISSN 0022-2860, IF2021 = 3.841].
  • Kratky M., Sramel P., Bodo P., Soltesova Prnova M., Kovacikova L., Majekova M., Vinsova J.*, Milan Stefek M.* Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group. Europ. J. Med. Chem. 2023, 246, 114922 [ISSN 0223-5234, IF2021= 6.514]


  • Jamelah S. Al-Otaibi, Sheena Mary Y., Shyma Mary Y., Krátký M., Vinsova J., Gamberini M.C.  Concetration dependent SERS study of a bioactive methylsulfonyl derivative. Journal of Molecular Liquids. 2022, 367, 120557. [ISSN 0167-7322, IF2021 = 6.633].
  • Krátký M., Novotná E., Stolaříková J., Švarcová M., Vinšová J. Substituted N-phenylitaconamides as inhibitors of mycobacteria and mycobacterial isocitrate lyase, Eur. J. Pharm. Sci. 2022, 171, 106252. [ISSN 0928-0987, IF2021 = 5.112]
  • Bősze S.E., Horváth L.B., Krátký M., Pflégr V., Méhes E.L., Gyulai G., Kohut G., Babiczky A., Biri-Kovács B., Baranyai Z.E., Vinšová J. Host cell targeting of novel antimycobacterial 4-aminosalicylic acid derivatives with tuftsin carrier peptides. European Journal of Pharmaceutics and Biopharmaceutics 2022, 174, 111-130. [ISSN: 0939-6411, IF2020= 5.571]
  • Pflégr V., Stolaříková J., Vinšová J., Krátký M. Synthesis and antimycobacterial activity of isoniazid derivatives tethered with aliphatic amines.  Curr. Top. Med. Chem, 2022, 22, 2695-2706. [IF2021 =3.570]. https://doi.10.2174/1568026622666220805152811
  • Pflégr V., Štěpánková Š., Svrčková K., Švarcová M., Vinšová J., Krátký M. 5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study. Pharmaceuticals 2022, 15, 400. [ISSN 1424-8247, IF2020= 5.863]


  • Pflégr V., Maixnerová J., Stolaříková J., Pál A., Korduláková J., Trejtnar F., Vinšová J., Krátký M. Design and Synthesis of Highly Active Antimycobacterial Mutual Esters of 2-(2-Isonicotinoylhydrazineylidene)propanoic Acid. Pharmaceuticals 2021, 14, 1229 [ISSN 1424-8247, IF2020= 5.863]
  • Krátký M., Konečná K., Janoušek J., Janďourek O., Maixnerová J., Kalivodová S., Trejtnar F., Vinšová J. Sulfonamide-salicylaldehyde imines active against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci. Future Med. Chem. 2021, 13(22),1945-1962. [ISSN (print): 1756-8919, (online): 1756-8927, IF2020 = 3.808].doi: 10.4155/fmc-2021-0169
  • Krátký M., Vu Q. A., Štěpánková Š., Maruca A., Silva T. B., Pflégr V., Ambrož M., Rocca R., Vorčáková K., Alcaro S., Borges F., Vinšová J. Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study. Bioorg. Chem. 2021, 116, 105301 [ISSN 0968-0896, IF2020 = 5.275].
  • Ghada Bouz G., Bouz S., Janďourek O., Konečná K., Bárta P., Vinšová J., Doležal M., Zitko J. Synthesis, Biological Evaluation, and In Silico Modelling of N-substituted Quinoxaline-2-carboxamides. Pharmaceuticals 2021, 14, 768. [ISSN 1424-8247, IF2020= 5.863]
  • Pflégr V., Horváth L., Stolaříková J., Pál A., Korduláková J., Bősze S., Vinšová J., Krátký M. Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity. Europ. J. Med. Chem. 2021, 223(5), 113668. [ISSN 0223-5234, IF2020= 6.514]
  • Krátký M., Konečná K., Brablíková M., Janoušek J., Pflégr V., Maixnerová J., Trejtnar F., Vinšová J. Iodinated 1,2-diacylhydrazines, benzohydrazide-hydrazones and their analogues as dual antimicrobial and cytotoxic agents. Bioorg. Med. Chem. 2021, 41, 116209. [ISSN: 0968-0896 , IF2020 = 3.641]
  • Baranyai, Z., Biri-Kovács B., Krátký M., Szeder B., Debreczeni M.L., Budai J., Kovács B., Horváth L., Pári E., Németh Z., Cervenak L., Zsila F., Méhes E., Kiss E., Vinšová J., Bosze, S. Cellular internalization and inhibition capacity of new anti-glioma peptide conjugates: Physicochemical characterization and evaluation on various monolayer- and 3D spheroid-based in vitro platforms. J. Med. Chem. 2021, 64, 6, 2982–3005 [ISSN 0022-2623, IF2020 = 7.446].
  • Veena S. Kumar, Y.Shyma Mary, Krátký M., Vinsova J., Baraldi C., Roxy M.S., Gamberini M.C. Spectroscopic investigations, concentration dependent SERS, and molecular docking studies of a hydroxybenzylidene derivative Journal of Biomolecular Structure and Dynamics 2021, [ISSN 0739-1102, IF2018 = 3,31]
  • Y.Sheena Mary, Y.Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. DFT, molecular docking and SERS (concentration and solvent dependant) investigations of a methylisoxazole derivative with potential antimicrobial activity. Journal of Molecular Structure 2021, 1232, 130034 [ISSN 0022-2860, IF2020 = 3.196].
  • Krátký M., Svrčková K, Vu Q. A., Štěpánková Š., Vinšová J. Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase. Molecules 2021, 26, 989[ISSN 1420-3049,IF2020 = 4.411].
  • Y. Sheena Mary, Y. Shyma Mary, Armaković S., Armaković S.J, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. Concentration and solvent dependent SERS, DFT, MD simulations and molecular docking studies of a thio xothiazolidine derivative with antimicrobial properties. Journal of Molecular Liquids, 2021, 329, 115582 [ISSN 0167-7322, IF2020 = 6.165].
  • Krátký M., Konečná K., Brokešová K., Maixnerová J., Trejtnar  F., Vinšová J. Optimizing the structure of (salicylideneamino)benzoic acids: Towards selective antifungal and anti-staphylococcal agents, Eur. J. Pharm. Sci. 2021, 159, 105732 [ISSN 0928-0987, IF2020 = 4.384].
  • Y. Sheena Mary, Y.Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. Concentration dependent SERS, DFT and molecular docking studies of a ureido derivative with antitubercular properties. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 249, 2021, 119329 [ISSN 1386-1425, IF2019= 3.232].
  • Y. Sheena Mary, Y. Shyma Mary, Krátký M., Vinsova J., Baraldi C., Gamberini M.C. DFT, SERS-concentration and solvent dependent and docking studies of a bioactive benzenesulfonamide derivative Journal of Molecular Structure  2021, 1228, 129680. [ISSN 0022-2860, IF2020 = 3.196].
  • Gamberinia M. C., Y.Shyma Mary, Y.Sheena Mary, Krátký M., Vinsova J., Baraldi C. Spectroscopic investigations, concentration dependent SERS, and molecular docking studies of a benzoic acid derivative. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2021, 248(5), 119265 [ISSN 1386-1425, IF2020 = 4.098].


  • Krátký M., Baranyai Z., Štěpánková Š., Svrčková K., Švarcová M., Stolaříková J., Horváth L., Bősze S., Vinšová J. N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1- carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity. Molecules 2020, 25, 2268; https.//  [ISSN 1420-3049, IF2020 = 4.411].
  • Ambrożkiewicz W., Kučerová-Chlupáčová M., Janďourek O., Konečná K., Paterová P., Bárta P., Vinšová J., Doležal M., Zitko J. 5-Alkylamino-N-Phenylpyrazine-2-Carboxamides: Design, Preparation, And Antimycobacterial Evaluation. Molecules 2020, 25, 1561;  [ISSN 1420-3049, IF2020 = 4.411].
  • Krátký M., Konečná K., Janoušek J., Brablíková M., Janďourek O., Trejtnar F., Stolaříková J., Vinšová J. 4-Aminobenzoic acid derivatives: Converting folate precursor to antimicrobial and cytotoxic agents. Biomolecules 2020, 10, 9, 1-21. doi:10.3390/biom10010009. [IF2020= 4,879].
  • Krátký M., Jaklová K., Štěpánková Š., Svrčková K., Pflégr V., Vinšová J. N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors. Curr. Top. Med. Chem. 2020, 20(23), 2094-2105. [IF2020 =3.295]
  • Krátký M., Štěpánková Š., Brablíková M., Svrčková K. Švarcová M., Vinšová J. Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors. Curr. Top. Med. Chem. . 2020, 20, (23), 2106-2117. [IF2020 =3.295].


  • Krátký M., Štěpánková Š., Houngbedji Neto-Honorius, Vosátka R., Vorčáková K., Vinšová J. 2-Hydroxy-N-phenylbenzamides and their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase. Biomolecules 2019, 9, 698; doi:10.3390/biom9110698, [IF2019= 4,082]]
  • Krátký M., Janďourek O., Baranyai Zs., Novotná E., Stolaříková J., Bősze S., Vinšová J. Phenolic N-monosubstituted carbamates: Antitubercular and toxicity evaluation of multi-targeting compounds. Europ. J. Med. Chem. 2019, 181, 111578 [ISSN 0223-5234, IF2019= 5.572].


  • Krátký M., Vorčáková K., Vinšová J., Štěpánková Š. Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase, Bioorganic Chemistry. 2018, 80, 668-673 [ISSN 0968-0896, IF2017 = 3.929].
  • Zitko J., Janďourek O., Paterová P., Navrátilová L., Kuneš J., Vinšová J., Doležal M. Design, synthesis and antimycobacterial activity of hybrid molecules combining pyrazinamide with 4-phenylthiazol-2-amine scaffold. MedChemComm, 2018. 9(4), 685-696. [ISSN 2040-2503], IF2017 = 2.342, doi:
  • Pospíšilová Š., Michnová H., Pauk K., Vinšová J., Imramovský A., Čížek A., Jampílek J. In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. Bioorg. Med. Chem. Letters 2018, 28, 2184-2188. [ISSN 0960-894X, IF2017 = 2.442]
  • Vosátka R., Krátký M., Švarcová M., Janoušek J., Stolaříková J., Madacki J., Husza  S., Mikušová K., Korduláková J.,Trejtnar F., Vinšová J. New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action. Europ. J. Med. Chem. 2018,151, 824-835. [ISSN 0223-5234, IF2017 = 4,816]
  • Vosátka R., Krátký M., Vinšová J. Triclosan and its derivatives as antimycobacterial active agents Eur. J. Pharm. Sci. 2018, 114, 318–331. [ISSN 0928-0987, IF2016 = 3.466].


  • Krátký M., Bősze S., Baranyai Zs., Stolaříková J., Vinšová J. Synthesis and biological evolution of hydrazones derived from 4-(trifluoromethyl)benzohydrazide. Bioorg. Med. Chem. Lett. 2017, 27,5185-5189. [ISSN 0960-894X, IF2017 = 2.442]. doi: 10.1016/j.bmcl.2017.10.050
  • Krátký M., Dzurková M., Janoušek O., Konečná K., Trejtnar F., Stolaříková J., Vinšová J. Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity. Molecules 2017, 22, 1573 [ISSN 1420-3049, IF2017 = 3.098]. doi:10.3390/molecules22091573
  • Krátký M., Stolaříková J., Vinšová J. Antimicrobial activity of rhodanine-3-acetic acid derivatives. Bioorg. Med. Chem. 2017, 25(6), 1839–1845 [ISSN 0968-0896, IF2017 = 2.881].
  • Baranyai Zs, Krátký M., Vosátka M., Szabó N., Senoner Sz., Dávid S., Stolaříková J., Vinšová J., Bősze S. In vitro biological evaluation of new antimycobacterial salicylanilide-tuftsin conjugates. Europ. J. Med. Chem. 2017, 133, 152-173 [ISSN 0223-5234, IF2017 = 4.816].
  • Krátký M., Stolaříková J., Vinšová J. Novel Sulfamethoxazole Ureas and Oxalamides as Potential Antimicobacterial Agents. Molecules 2017, 22(4), 535 [ISSN 1420-3049, IF2017 = 3.098]. doi:10.3390/molecules22040535
  • Krátký M., Vinšová J., Štěpánková Š., Vorčáková K., Navrátilová L., Trejtnar F., Stolaříková J. Novel Fluorophenylalanine Derivatives: Synthesis and Investigation of Their Biological Activity. Bioorganic Chemistry 2017, 71, 244 - 256 [ISSN: 0045-2068, IF2017 = 3.929].
  • Paraskevopoulos G., Monteiro S., Vosátka R., Krátký M., Navrátilová L., Trejtnar F., Stolaříková J., Vinšová J. Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. Bioorg. Med. Chem. 2017, 25(4), 1524-1532 [ISSN 0968-0896, IF2017 = 2.881]. 


  • Krátký M.*, Štěpánková Š., Vorčáková K., Vinšová J. Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors. Bioorganic Chemistry 2016, 68, 23-29  [ISSN 0045-2068, IF2016 = 3.231].
  • Kozic J.*, Novák Z., Římal V., Profant V., Kuneš J., Vinšová J. Conformations, equilibrium thermodynamics and rotational barriers of secondary thiobenzanilides. Tetrahedron, 2016, 72, 2072-2083 [ISSN: 0040-4020, IF2016 = 2.651]. doi:10.1016/j.tet.2016.02.035
  • Krátký M.*, Vinšová J. Salicylanilide N-monosubstituted carbamates: Synthesis and in vitro antimicrobial activity. Bioorg. Med. Chem. 201624(6), 1322-1330.   [ISSN 0968-0896, IF20156= 2.930].
  • Krátký M.*, Štěpánková Š., Vorčáková K., Švarcová M, Vinšová J. Novel Cholinesterases Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamate, Molecules, 201621, 191-201. [ISSN 1420-3049, IF2016 = 2.861].
  • Krátký M.*, Vinšová J. Sulphur-Containing Heterocycles as Antimycobacterial Agents: Recent Advances in Thiophene and Thiadiazole Derivatives, Current Topics in Medicinal Chemistry, 201616(26), 2921-2952 [ISSN 1389-4501, IF2016 = 2.561]. DOI: 10.2174/1568026616666160506131118


  • Krátký M., Štěpánková Š, Vorčáková K., Vinšová J.* Salicylanilide Diethyl Phosphates as Cholinesterases Inhibitors. Bioorg. Med. Chem. 2015, 58, 48-52. [ISSN 0968-0896, IF2015 = 2.923].
  • Zadrazilova I., Pospisilova S., Pauk K., Imramovsky A., Vinsova J., Cizek A., Jampilek J.* In vitro bactericidal activity of 4- and 5-chloro-2-hydroxy-N-[1-oxo-1-(phenylamino)alkan-2-yl]benzamides against MRSA, BioMed Research International, 2015 Article 349534[ISSN 2314-6133, IF2014 = 1.579].
  • Krátký M., Bősze S., Baranyai Zs., Szabó I., Stolaříková J., Paraskevopoulos G., Vinšová J.* Synthesis and In Vitro Biological Evaluation of 2-(Phenylcarbamoyl)phenyl 4-Substituted Benzoates. Bioorg. Med. Chem. 201524(4), 868–875.  [ISSN 0968-0896, IF2015 = 2.793].
  • Švarcová M., Krátký M., Vinšová J*. Investigation of potential inhibitors of chorismate-utilizing enzymes Curr. Med. Chem. 2015, 22(11), 1383-1399 [ISSN 0929-8673, IF2015 = 3.853].
  • Krátký M.*, Mandíková J., Trejtnar F., Buchta V., Stolaříková J., Vinšová J. Synthesis and antimicrobial activity of novel sulfamethoxazole ureas and 2,4,5- imidazolidin-2,4,5-triones. Chemical Papers,  2015, 69(8), 1108-1117. [ISSN 0366-6352, IF2015 = 1.326].
  • Zadrazilova I., Masarikova M., Pospisilova S., Imramovsky A., Ferriz J.M., Vinsova J., Cizek J., Jampilek J.* Salicylanilide carbamates: Promising antibacterial agents with high in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA), Eur. J. Pharm. Sci., 2015, 77, 197-207. [ISSN 0928-0987, IF2015 = 3.350].
  • Baranyai Z., Krátký M., Vinšová J., Szabó N., Senoner Z., Horváti K., Stolaříková J., Dávid S., Bősze S.* Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates. Europ. J. Med. Chem. 2015101, 692-704. [ISSN 0223-5234, IF2015 = 3.447].
  • Paraskevopoulos G., Krátký M., Mandíková J., Trejtnar F., Stolaříková J., Pávek P., Besra G.,Vinšová J.* Novel derivatives of nitro-substituted salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. Bioorg. Med. Chem. 2015, 23, 7292-7301 [ISSN 0968-0896, IF2015 = 2.923].











© Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
Website information | Powered by Kentico