Department of Pharmacology and Toxicology and Centre for Drug Development, Professor
Laboratory of Clinical and Molecular Pharmacotherapy
e-mail: Pavek@faf.cuni.cz
address: Heyrovského 1203, Hradec Kralove 500 05
phone: +420 495 067 334
New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM
Článek v magazínu UK Forum.: Farmaceutická fakulta UK má výzkumný projekt za půl miliardy korun
M.Sc. 1996 – Faculty of Pharmacy, Charles University in Prague
Ph.D. 2000 – Pharmacology and Toxicology - Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University in Prague
Assistant, 2000-2008, Associate Professor 2008
Professor 2014 - present, Department of Pharmacology and Toxicology
Aspects of gene regulation of proteins involved in pharmacokinetics, nuclear receptors, cytochrome P450 gene regulation, pharmacokinetics (DMPK), ADME-Tox, Drug-drug and drug-food interactions, pharmacogenetics and drug development
Pharmacology and toxicology, Personalized pharmacotherapy and pharmacogenetics, Gene therapy, Biologics
Dynamics of nuclear receptor-mediated gene regulation:implement for the understanding of
detoxification functions and optimization of therapy GAČR 17-06841S, 2017-2019
Novel interventions for the treatment of triglycerides, cholesterol and bile acids diseases with
human CAR ligands 19-14497S 2019-2021
Horizon 2020 - Metabolic effects of Endocrine Disrupting Chemicals: novel testing methods and adverse outcome Pathways (EDCMET) 2018-2023
Horizon 2020 COST action - The European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP)
2024 – Česká hlava /Prize LOREM
2002, 2003, 2006, 2009, 2011 – Award of the Czech Society for Experimental and Clinical Pharmacology and Toxicology - as a first author
2004 – Stasek´s Award in Oncology by Janssen Foundation
2003 – The International Pharmaceutical Federation Fellowship
2001-2003- the Czech Science Foundation POST-DOC Fellowship
2017 – Award of the Czech Medical Society of J.E. Perkynje