Mgr. Zuzana Lomozová

Research focus

  • Interactions of natural compounds with biogenic metals
  • In vitro screening of novel iron/copper/zinc/cobalt chelators (comparison of chelating activity at different pHs, assessment of the abilities of these compounds to inhibit Fenton chemistry leading to highly reactive oxygen species and tissue derangement)

Education

  • 2014-2019: Charles University, Faculty of Pharmacy, (Master degree), Thesis: Interactions of tamarixetin and isorhamnetin with copper.
  • from 2019: a postgraduate study at Charles University, Faculty of Pharmacy, Department of Pharmacognosy and Pharmaceutical Botany in the study programme: Pharmacognosy and Nutraceuticals. Doctoral Thesis theme: Interactions of natural phenolic compounds with biogenic metals.

Employment

  • from 2022: Charles University, Faculty of Pharmacy in Hradec Králové, Department of Pharmacognosy and Pharmaceutical Botany

Teaching activities

  • Pharmacognosy (practicals)

Research fellowships

  • 2021 research fellowship at the Department of Pharmacology, University of Pécs (3 months)

Publications

2021

LOMOZOVÁ Z, CATAPANO M C, HRUBŠA M, KARLÍČKOVÁ J, MACÁKOVÁ K, KUČERA R, MLADĚNKA P: Chelation of Iron and Copper by Quercetin B-Ring Methyl Metabolites, Isorhamnetin and Tamarixetin, and Their Effect on Metal-Based Fenton Chemistry. J. Agric. Food Chem. 2021, 69(21), 5926–5937, DOI: 10.1021/acs.jafc.1c01729. /IF2019 4.2/

LOMOZOVÁ Z, TVRDÝ V, HRUBŠA M, CATAPANO M C, MACÁKOVÁ K, BIEDERMANN D, KUČERA R, KŘEN V, MLADĚNKA P, VALENTOVÁ K: Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo. Antioxidants 2021, 10(5), 679, DOI: 10.3390/antiox10050679. /IF2019=5.0/

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