Petr Pavek, PhD, Professor

Department of Pharmacology and Toxicology and Centre for Drug Development, Professor

Laboratory of Clinical and Molecular Pharmacotherapy
address: Heyrovského 1203, Hradec Kralove 500 05
phone: +420 495 067 334

Chair of Local Scientific Committee
The 25th International Symposium on Microsomes and Drug Oxidations
„Microsomes and Drug Oxidations: From Structures to Regulations and Modeling“
Prague, Czech Republic

MDO Prague

Previous Education and Emplyoment

M.Sc. 1996 – Faculty of Pharmacy, Charles University in Prague

Ph.D. 2000 – Pharmacology and Toxicology - Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University in Prague

Assistant, 2000-2008, Associate Professor 2008

Professor 2014 - present, Department of Pharmacology and Toxicology

Research Interests

Aspects of gene regulation of proteins involved in pharmacokinetics, nuclear receptors, cytochrome P450 gene regulation, pharmacokinetics (DMPK), ADME-Tox, Drug-drug and drug-food interactions, pharmacogenetics and drug development


Pharmacology and toxicology, Personalized pharmacotherapy and pharmacogenetics, Gene therapy, Biologics

Professional Memberships

  • Scientific Secretary of the Czech Society for Experimental and Clinical Pharmacology and Toxicology
  • Chair of the Section of Cellular and Molecular Pharmacology CSECPT
  • Advisory Board of Czech Scientific Foundation

Current grants

GA ČR Dynamics of nuclear receptor-mediated gene regulation:implement for the understanding of
detoxification functions and optimization of therapy GAČR 17-06841S, 2017-2019  

GA ČR Novel interventions for the treatment of triglycerides, cholesterol and bile acids diseases with
human CAR ligands 19-14497S 2019-2021       

edcmet Horizon 2020 - Metabolic effects of Endocrine Disrupting Chemicals: novel testing methods and adverse outcome Pathways (EDCMET) 2018-2023

UNGAP Horizon 2020 COST action - The European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP)


2002, 2003, 2006, 2009, 2011 – Award of the Czech Society for Experimental and Clinical Pharmacology and Toxicology - as a first author

2004 – Stasek´s Award in Oncology by Janssen Foundation

2003 – The International Pharmaceutical Federation Fellowship

2001-2003- the Czech Science Foundation POST-DOC Fellowship

2017 – Award of the Czech Medical Society of J.E. Perkynje


© Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 03 Hradec Králové, Czech Republic
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