Previous Education and Emplyoment
M.Sc. 1996 – Faculty of Pharmacy, Charles University in Prague
Ph.D. 2000 – Pharmacology and Toxicology - Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University in Prague
Assistant, 2000-2008, Associate Professor 2008
Professor 2014 - present, Department of Pharmacology and Toxicology
Research Interests
Aspects of gene regulation of proteins involved in pharmacokinetics, nuclear receptors, cytochrome P450 gene regulation, pharmacokinetics (DMPK), ADME-Tox, Drug-drug and drug-food interactions, pharmacogenetics and drug development
Teaching
Pharmacology and toxicology, Personalized pharmacotherapy and pharmacogenetics, Gene therapy, Biologics
Professional Memberships
- Scientific Secretary of the Czech Society for Experimental and Clinical Pharmacology and Toxicology
- Chair of the Section of Cellular and Molecular Pharmacology CSECPT
- Advisory Board of Czech Scientific Foundation
Current grants
Dynamics of nuclear receptor-mediated gene regulation:implement for the understanding of
detoxification functions and optimization of therapy GAČR 17-06841S, 2017-2019
Novel interventions for the treatment of triglycerides, cholesterol and bile acids diseases with
human CAR ligands 19-14497S 2019-2021
Horizon 2020 - Metabolic effects of Endocrine Disrupting Chemicals: novel testing methods and adverse outcome Pathways (EDCMET) 2018-2023
Horizon 2020 COST action - The European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP)
Awards/Prizes/Fellowships
2002, 2003, 2006, 2009, 2011 – Award of the Czech Society for Experimental and Clinical Pharmacology and Toxicology - as a first author
2004 – Stasek´s Award in Oncology by Janssen Foundation
2003 – The International Pharmaceutical Federation Fellowship
2001-2003- the Czech Science Foundation POST-DOC Fellowship
2017 – Award of the Czech Medical Society of J.E. Perkynje
Publications