Scientific cooperation


  • Prof. dr. Jacqueline Cloos, dr. Gerrit Jansen - Department of Hematology, Amsterdam UMC, Netherland
    • characterisation of leukemic cells resistant to FLT3 inhibitors
  • Dr. Csilla Özvegy-Laczka - Membrane Protein Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary
    • cooperation in the topic of OATP transporters, evaluation of membrane transporters associated mechanisms of resistance
  • Assoc. Prof. Dr. Christian Wadsack - Medical University of Graz, Department of Obstetrics and Gynecology, Graz, Austria
    • collaboration on placental transport and involvement of ABC as well as SLC transporters, in particular dual perfusion of human placenta and ex vivo isolated primary cell cultures
  • Assoc. Prof. Dr. Claudia Gundacker & Assoc. Prof. Dr. Isabella Ellinger – Medical University of Vienna, Vienna, Austria
    • Collaboration in the investigation of placental MRP1 transporter, transporter visualisation
  • Dr. Jocelyn Glazier & Dr. Susane Greenwood – St. Mary´s Hospital, University of Manchester, Great Britain
    • collaboration on SLC transporters in transplacental transfer of drugs

In the Czech Republic

  • prof. MUDr. Pavel Žák, Ph.D., MUDr. Benjamín Víšek & MUDr. Alžběta Zavřelová – University Hospital Hradec Králové, The 4th Department of Internal Medicine – Hematology
    • clinical part of the research, collection of  samples from patients diagnosed for acute leukemia
  • RNDr. Ondřej Souček, Ph.D. – University Hospital Hradec Králové, Department of Clinical Immunology and Allergology
    • identification of leukemia-associated immunophenotypes
  • Mgr. Marie Vajrychová, Ph.D. - Biomedical Research Center, University Hospital Hradec Králové
    • proteomic analysis 
  • Assoc. Prof. PharmDr. Jan Korábečný, Ph.D. - Biomedical Research Center, University Hospital Hradec Králové
    • synthesis of new anti-AML compounds
  • prof. MUDr. Martina Řezáčová, Ph.D. - Medical Faculty Hradec Králové, Charles University
    • analysis of apoptotic signalling pathways in drug resistance
  • Prof. MUDr. Marian Kacerovský, Ph.D. – University Hospital Hradec Králové, Department of Obstetrics and Gynecology
    • collection of placental tissue, umbilical cord and cord blood, collaboration in the topic of ABC/SLC transporters in preterm birth
  • Assoc. Prof. RNDr. Vladimír Kryštof, Ph.D. – University of Olomouc, Laboratory of Growth Regulators
    • cooperation on characterisation of new investigational drugs of cyclin-dependent kinase inhibitor group

At the Faculty of Pharmacy

  • Prof. Ing. Vladimír Wsól, Ph.D., RNDr. Eva Novotná, Ph.D. – Department of Biochemical Sciences
    • collaboration on drug resistance to anthracyclines (carbonyl reductases associated mechanisms of drug resistance) and molecular docking
  • Assoc. Prof. PharmDr. Radim Kučera, Ph.D. & Prof. PharmDr. Lucie Nováková, Ph.D. – Department of Pharmaceutical Chemistry and Drug Analysis
    • chemical analysis of the investigated drugs
  • Assoc. Prof. Jakub Hofman, Ph.D. – Department of Pharmacology and Toxicology
    • pharmacokinetic resistance and its modulation by novel targeted drugs


© Charles University, Faculty of Pharmacy in Hradec Králové, Akademika Heyrovského 1203, 500 03 Hradec Králové, Czech Republic
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