2022
Sucha, S., Sorf, A., Svoren, M., Vagiannis, D., Ahmed, F., Visek, B., & Ceckova, M. (2022). ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia. Biomed Pharmacother, 150, 112962. doi:10.1016/j.biopha.2022.112962
2021
Sorf, A., Vagiannis, D., Ahmed, F., Hofman, J., and Ceckova, M. "Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy." Toxicol Appl Pharmacol, 2021. 434: p.115797. https://doi.org/10.1016/j.taap.2021.115797
2020
Granitzer, S., Ellinger, I., Khan, R., Gelles, K., Widhalm, R., Hengstschlager, M., Zeisler, H., Desoye, G., Tupova, L., Ceckova, M., Salzer, H., and Gundacker, C. "In Vitro Function and in Situ Localization of Multidrug Resistance-Associated Protein (Mrp)1 (Abcc1) Suggest a Protective Role against Methyl Mercury-Induced Oxidative Stress in the Human Placenta." Arch Toxicol (Sep 11 2020). https://dx.doi.org/10.1007/s00204-020-02900-5.
Tupova, L., Hirschmugl, B., Sucha, S., Pilarova, V., Szekely, V., Bakos, E., Novakova, L., Ozvegy-Laczka, C., Wadsack, C., and Ceckova, M. "Interplay of Drug Transporters P-Glycoprotein (Mdr1), Mrp1, Oatp1a2 and Oatp1b3 in Passage of Maraviroc across Human Placenta." Biomed Pharmacother 129 (Sep 2020): 110506. https://dx.doi.org/10.1016/j.biopha.2020.110506.
Karbanova, S., Sorf, A., Jiraskova, L., Lalinska, A., Ptackova, Z., Staud, F., and Cerveny, L. "S-(4-Nitrobenzyl)-6-Thioinosine (Nbmpr) Is Not a Selective Inhibitor of Equilibrative Nucleoside Transporters but Also Blocks Efflux Activity of Breast Cancer Resistance Protein." Pharm Res 37, no. 3 (Feb 21 2020): 58. https://dx.doi.org/10.1007/s11095-020-2782-5.
Sorf, A., Sucha, S., Morell, A., Novotna, E., Staud, F., Zavrelova, A., Visek, B., Wsol, V., and Ceckova, M. "Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with Cdk4/6 Inhibitors." Cancers (Basel) 12, no. 6 (Jun 16 2020). https://dx.doi.org/10.3390/cancers12061596.
2019
Hofman, J., Sorf, A., Vagiannis, D., Sucha, S., Kammerer, S., Kupper, J. H., Chen, S., Guo, L., Ceckova, M., and Staud, F. "Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human Abcg2 Drug Efflux Transporter and Cyp450 Biotransformation Enzymes." Mol Pharm 16, no. 11 (Nov 4 2019): 4436-50. https://dx.doi.org/10.1021/acs.molpharmaceut.9b00361.
Hofman, J., Sorf, A., Vagiannis, D., Sucha, S., Novotna, E., Kammerer, S., Kupper, J. H., Ceckova, M., and Staud, F. "Interactions of Alectinib with Human Atp-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance." Drug Metab Dispos 47, no. 7 (Jul 2019): 699-709. https://dx.doi.org/10.1124/dmd.119.086975.
Sorf, A., Novotna, E., Hofman, J., Morell, A., Staud, F., Wsol, V., and Ceckova, M. "Cyclin-Dependent Kinase Inhibitors Azd5438 and R547 Show Potential for Enhancing Efficacy of Daunorubicin-Based Anticancer Therapy: Interaction with Carbonyl-Reducing Enzymes and Abc Transporters." Biochem Pharmacol 163 (May 2019): 290-98. https://dx.doi.org/10.1016/j.bcp.2019.02.035.
Tupova, L., Ceckova, M., Ambrus, C., Sorf, A., Ptackova, Z., Gaborik, Z., and Staud, F. "Interactions between Maraviroc and the Abcb1, Abcg2, and Abcc2 Transporters: An Important Role in Transplacental Pharmacokinetics." Drug Metab Dispos 47, no. 9 (Sep 2019): 954-60. https://dx.doi.org/10.1124/dmd.119.087684.
2018
Sorf, A., Hofman, J., Kucera, R., Staud, F., and Ceckova, M. "Ribociclib Shows Potential for Pharmacokinetic Drug-Drug Interactions Being a Substrate of Abcb1 and Potent Inhibitor of Abcb1, Abcg2 and Cyp450 Isoforms in Vitro." Biochem Pharmacol 154 (Aug 2018): 10-17. https://dx.doi.org/10.1016/j.bcp.2018.04.013