Publications since 2005
2023
Nawrot D. E., Bouz G., Jandourek O., Konecná K., Paterová P., Bárta P., Novák M., Kucera R., Zemanová J., Forbak M., Korduláková J., Pavlis O., Kubícková P., Dolezal M., Zitko J. Antimycobacterial pyridine carboxamides: From design to in vivo aktivity. European Journal of Medicinal Chemistry. 2023; 258: 115617. (IF 2022 = 6.7)
Moravcová M., Lomozová Z., Kucera R., Mercolini L., Mladenka P. 3-Hydroxyflavone is a mildly active and safe cobalt chelator while cobalt markedly enhances baicalein toxicity toward erythrocytes. RSC Advances. 2023; 13(43): 29242-29251. (IF 2022 = 3.9)
Novak M., Vajrychova M., Koutsilieri S., Sismanoglou D. C., Kobrlova T., Prchal L., Svobodova B., Korabecny J., Zarybnicky T., Raisova-Stuchlikova L., Skalova L., Lauschke V. M., Kucera R., Soukup O. Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation. ACS Chemical Biology. 2023; 18(9): 1993-2002. (IF 2022 = 4.0)
Abad C., Karahoda R., Orbisova A., Kastner P., Heblik D., Kucera R., Portillo R., Staud F. Pathological shifts in tryptophan metabolism in human term placenta exposed to LPS or poly I:C. Biology of Reproduction. 2023; ioad181. (IF 2022 = 3.6)
Moravcová M., Hrubsa M., Lomozová Z., Catapano M.C., Argento R., Jirkovský E., Kucera R., Mercolini L., Mladenka P. A Complex Methodological Approach for the Screening of Efficient and Safe Cobalt Chelators. Medicinal Chemistry. 2023; 19(5): 495-507. (IF2022 = 2.3)
Plachká K., Pilařová V., Horáček O., Gazárková T., Kočová Vlčková H., Kučera R., Nováková L. Columns in analytical-scale supercritical fluid chromatography: From traditional to unconventional chemistries. Journal of Separation Science. 2023; 46(5): e2300431. (IF2022 = 3.1)
Khalikova M., Jireš J., Horáček O., Douša M., Kučera R., Nováková L. What is the role of current mass spectrometry in pharmaceutical analysis? Mass Spectrometry Reviews. 2023; 1-50. (IF2022 = 6.7)
Portillo A., Dhaubhadel U., Horáček O., Sung Y-S., Armstrong D.W. Investigating chirality in quorum sensing by analysis of Burkholderia cepacia and Vibrio fischeri with comprehensive chiral LC-MS/MS and GC-MS/MS methods. FEMS Microbiology Letters. 2023; 370: fnad011. (IF2022 = 2.1)
Dhaubhadel U., Portillo A., Horáček O., Sung Y-S., Armstrong D.W. Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa. PLoS One. 2023; 18(3): e0283657. (IF2022 = 3.7)
Horáček O., Dhaubhadel U., Holub J., Grüner B., Armstrong D.W., Kučera R. Employment of chiral columns with superficially porous particles in chiral separations of cobalt bis (dicarbollide) and nido-7,8-C2 B9 H12 (1-) derivatives. Chirality. 2023; 35(12): 937-951.
(IF2022 = 1.7)
Kerda M., Šlechta P., Jand'ourek O., Konečná K., Hatoková P., Paterová P., Zitko J. N-Pyrazinylhydroxybenzamides as biologically active compounds: a hit-expansion study and antimicrobial evaluation. Future Medicinal Chemistry. 2023; 15(19). (IF2022 = 4.2)
Hatokova P., Sestak V., Bavlovic Piskackova H., Melnikova I., Roh J., Sterbova-Kovarikova P. The UHPLC-UV method applied for the forced degradation study of ixazomib and HRMS identification of its degradation products. Journal of Pharmaceutical and Biomedical Analysis. 2023; 225: 115220. (IF2022 = 3.4)
Novak M, Svobodova B, Konecny J, Kuratkova A, Nevosadova L, Prchal L, Korabecny J, Lauschke VM, Soukup O, Kučera R. UHPLC-Orbitrap study of the first phase tacrine in vitro metabolites and related Alzheimer's drug candidates using human liver microsomesJ. Journal of Pharmaceutical and Biomedical Analysis. 2023; 224: 115154. (IF2022 = 3.4)
Bouz G, Šlechta P, Jand'ourek O, Konečná K, Paterová P, Bárta P, Novák M, Kučera R, Dal NK, Fenaroli F, Zemanová J, Forbak M, Korduláková J, Pavliš O, Kubíčková P, Doležal M, Zitko J. Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid. ACS Infection diseases. 2023; 9(1): 79-96. (IF2022 = 5.1)
Horáček O., Portillo A.E., Dhaubhadel U., Sung Y., Readel E.R., Kučera R., Armstrong D.W. Comprehensive chiral GC-MS/MS and LC-MS/MS methods for identification and determination of N-acyl homoserine lactones. Talanta. 2023; 253: 123957. (IF2022 = 6.1)
2022
Horáček O., Nováková L., Tüzün E., Grüner B., Švec F., Kučera R. Advanced Tool for Chiral Separations of Anionic and Zwitterionic (Metalla)carboranes: Supercritical Fluid Chromatography. Analytical Chemistry. 2022; 94: 17551-17558. (IF2022 = 7.4)
Lomozová Z, Hrubša M, Conte PF, Papastefanaki E, Moravcová M, Catapano MC, Proietti Silvestri I, Karlíčková J, Kučera R, Macáková K, Mladěnka P. The effect of flavonoids on the reduction of cupric ions, the copper-driven Fenton reaction and copper-triggered haemolysis. Food Chemistry. 2022; 394: 133461. (IF2022 = 8.8)
Kostelansky F, Miletin M, Havlinova Z, Szotakova B, Libra A, Kucera R, Novakova V, Zimcik P. Thermal stabilisation of the short DNA duplexes by acridine-4-carboxamide derivatives. Nucleic Acids Research. 2022; ;50(18): 10212-10229. (IF2022 = 14.9)
Demuth J, Kantor M, Kucera R, Miletin M, Novakova V. Comparison of Quenching Efficiencies in Long Triple-Labeled and Double-Labeled TaqMan Oligodeoxynucleotide Probes. Bioconjugate Chemistry. 2022; 33(5): 788-794. (IF2022 = 4.7)
Juhás M., Bachtíková A., Nawrot D.E., Hatoková P., Pallabothula V.S.K., Diepoltová A., Janďourek O., Bárta P., Konečná K., Paterová P., Šesták V., Zitko J. Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole. Pharmaceuticals. 2022; 15(5): 580. (IF2022 = 4.6)
Horáček O., Marvalová J., Štilcová K., Holub J., Grüner B., Kučera R. Reversed-phase chromatography as an effective tool for the chiral separation of anionic and zwitterionic carboranes using polysaccharide-based chiral selectors. Journal of Chromatography A. 2022; 1672 : 463051. (IF2022 = 4.1)
Pavek P., Dusek J., Smutny T., Lochman L., Kucera R., Skoda J., Smutna L., Kamaraj R., Soucek P., Vrzal R., Dvorak Z. Gene Expression Profiling of 1α,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes. Molecular Nutrition and Food Research. 2022; 2200070: 1-17. (IF2022 = 5.2)
El Anwar S., Pazderová L., Bavol D., Bakardjiev M., Ruzickova Z., Horáček O., Fojt L., Kucera R., Gruner B. Structurally rigidified cobalt bis(dicarbollide) derivatives, a chiral platform for labelling of biomolecules and new materials. Chemical Communications, 2022, 58, 2572–2575. (IF2022 = 4.9)
Bavlovič Piskáčková H, Nemeškalová A, Sýkora D, Kučera R, Pedersen-Bjergaard, S, Najmanová V, Štěrbová-Kovaříková P, Kuchař M. Advanced microextraction techniques for the analysis of amphetamines in human breast milk and their comparison with conventional methods. Journal of Pharmaceutical and Biomedical Analysis. 2022; 210: 114549. (IF2022 = 3.4)
2021
Demuth J, Gallego L, Kozlikova M, Machacek M, Kucera R, Torres T, Martinez-Diaz MV, Novakova V. Subphthalocyanines as Efficient Photosensitizers with Nanomolar Photodynamic Activity against Cancer Cells. Journal Medicinal Chemistry. 2021: 64(23): 17436-17447. (IF2021=8.039)
Lomozová Z, Tvrdý V, Hrubša M, Catapano MC, Macáková K, Biedermann D, Kučera R, Křen V, Mladěnka P, Valentová K. Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo. Antioxidants (Basel). 2021;10(5): 679. (IF2021=7.675)
Vanova N., Hojná A., Pejchal J., Herman D., Malinak D., Prchalova E., Musilek K., Zdarova-Karasova J. Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study. Journal of Pharmaceutical Sciences. 2021; 110(4): 1842-1852. (IF2020=3.534)
Lomozová Z, Catapano MC, Hrubša M, Karlíčková J, Macáková K, Kučera R, Mladěnka P. Chelation of Iron and Copper by Quercetin B-Ring Methyl Metabolites, Isorhamnetin and Tamarixetin, and Their Effect on Metal-Based Fenton Chemistry. Journal of Agricultural and Food Chemistry. 2021; 69(21): 5926-5937. (IF2021=5.895)
Kollárová-Brázdová P., Lenčová-Popelová O., Karabanovich G., Kocúrová-Lengvarská J., Kubeš J., Váňová N., Mazurová Y., Adamcová M., Jirkovská A., Holečková M., Šimůnek T., Štěrbová-Kovaříková P., Roh J., Štěrba M. Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo. Clinical Science. 2021; 135(15): 1897-1914. (IF2020=6.124)
Mžik M., Váňová N., Kriegelstein M., Hroch M. Differential adsorption of an analyte and its D4, D5 and 13C6 labeled analogues combined with instrument-specific carry-over issues: The Achilles' heel of ibrutinib TDM. Journal of Pharmaceutical and Biomedical Analysis. 2021, 206. (IF2020=3.935)
Dlabkova A., Herman D., Cechova L., Hroch M., Vanova N., Zdarova-Karasova J. 3‐Quinuclidinyl benzilate (agent BZ) toxicokinetics in rats. Basic & Clinical Pharmacology & Toxicology. 2021; 129(3): 246-255. (IF2020=4.048)
Jirkovská A., Karabanovich G., Kubeš J., Skalická V., Melnikova I., Korábečný J., Kučera T., Jirkovský E., Nováková L., Bavlovič Piskáčková H., Škoda J., Štěrba M., Austin C.A., Šimůnek T., Roh J. Structure-activity relationship study of dexrazoxane analogues reveals ICRF-193 as the most potent bisdioxopiperazine against anthracycline toxicity to cardiomyocytes due to its strong topoisomerase IIβ interactions. Journal of Medicinal Chemistry. 2021; 64(7): 3997-4019. (IF2020=6.18)
Jirkovský E., Jirkovská A., Bavlovič Piskáčková H., Skalická V., Pokorná Z., Karabanovich G., Brázdová P., Kubeš J., Lenčová-Popelová O., Mazurová Y., Adamcová M., Lyon A.R., Roh J., Šimůnek T., Štěrbová-Kovaříková P., Štěrba M. Clinically translatable prevention of anthracycline cardiotoxicity by dexrazoxane is mediated by topoisomerase IIβ and not metal chelation. Circulation: Heart Failure. 2021; (IF2020=8.790)
Bavlovič Piskáčková H., Jansová H., Kubeš J., Karabanovich G., Váňová N., Kollárová-Brázdová P., Melnikova J., Jirkovská A., Lenčová-Popelová O., Chládek J., Roh J., Šimůnek T., Štěrba M., Štěrbová-Kovaříková P., Development of water-soluble pro-drugs of bisdioxopiperazine topoisomerase IIβ inhibitor ICRF 193 as potential cardioprotective agents against anthracycline cardiotoxicity. Scientific reports. 2021; 11: 4456. (IF2020=3.998)
Bavlovič Piskáčková H., Kollárová-Brázdová P., Kučera R., Macháček M., Pedersen-Bjergaard S., Štěrbová-Kovaříková P., The electromembrane extraction of pharmaceutical compounds from animal tissues. Anal. Chim. Acta. 2021; 1177. (IF2020=6.558)
Halaskova M., Rahali A., Almeida-Marrero V., Machacek M., Kučera R., Jamoussi B., Torres, T., Novakova V., de la Escosura A., Zimcik P. Peripherally Crowded Cationic Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy. ACS Medicical Chemistry Letters. 2021; 12: 502-507. (IF2020=4.345)
Bavlovič Piskáčková H., Øiestad E.L., Váňová N., Lengvarská J., Štěrbová-Kovaříková P., Pedersen-Bjergaard S. Electromembrane extraction of anthracyclines from plasma: Comparison with conventional extraction techniques. Talanta. 2021; 223: 1-10. (IF2020=6.057)
Horáček O., Papajová-Janetková M., Grüner B., Lochman L., Štěrbová-Kovaříková P., Vespalec R., Kučera R. The first chiral HPLC separation of dicarba-nido-undecarborate anions and their chromatographic behavior. Talanta. 2021; 222: 121652. (IF2020=6.057)
Kučera R., Scensna A., Miletin M., Zimcik P. The chromatographic behaviour of new double-labelled oligodeoxynucleotide probes containing azaphthalocyanine dye as a quencher with respect to evaluation of their purity. Biomedical Chromatography. 2021; 35: e5033. (IF2020=1.902)
2020
Herman D., Dlabková A., Váňová N., Prchal l., Vajrychová M., Doležal R., Bzonek P., Jun D. OPCW biomedical proficiency test v laboratoři analytické chemie Katedry toxikologie a vojenské farmacie. Military Medical Science Letters. 2020; 89(3): 126-141.
Montesdeoca-Esponda S., Torres-Pardon M.E., Novak M., Krchova L., Sosa-Ferrera Z., Santana-Rodriguez JJ. Occurrence of benzotriazole UV stabilizers in coastal fishes. Journal of Environmental Management. 2020; 269: 1-8. (IF2019=5.647)
Godyn J., Gucwa D., Kobrlova T., Novak M., Soukup O., Malawska B., Bajda M. Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability. Talanta. 2020; 217: 1-14. (IF2019=5.339)
Abad C., Karahoda R., Kastner P., Portillo R., Horackova H., Kučera R., Nachtigal P., Staud F. Profiling of Tryptophan Metabolic Pathways in the Rat Fetoplacental Unit during Gestation. International Journal of Molecular Sciences. 2020; 21: 7578. (IF2019=4.556)
Karahoda R., Abad C., Horackova H., Kastner P., Zaugg J., Cerveny L., Kucera R., Albrecht Ch., Staud F. Dynamics of Tryptophan Metabolic Pathways in Human Placenta and Placental-Derived Cells: Effect of Gestation Age and Trophoblast Differentiation. Frontiers in Cell and Developmental Biology. 2020; 8: 1-15. (IF2019=5.186)
Kollar J., Machacek M., Halaskova M., Lenco J., Kucera R., Demuth J., Rohlickova M., Hasonova K., Miletin M., Novakova V., Zimcik P. Cationic Versus Anionic Phthalocyanines for Photodynamic Therapy: What a Difference the Charge Makes. Journal of Medicinal Chemistry. 2020; 63: 7616-7632. (IF2019=6.205)
Kollárová-Brázdová P., Jirkovská A., Karabanovich G., Pokorná Z., Bavlovič Piskáčková H., Jirkovský E., Kubeš J., Lenčová-Popelová O., Mazurová Y., Adamcová M., Skalická V., Štěrbová-Kovaříková P., Roh J., Šimůnek T., Štěrba M. Investigation of structure-activity relationships of dexrazoxane analogs reveals topoisomerase IIβ interaction as a prerequisite for effective protection against anthracycline cardiotoxicity. Journal of Pharmacology and Experimental Therapeutics. 2020; 373: 402-415. (IF2019=3.561)
Karahoda R., Horackova H., Kastner P., Matthios A., Cerveny L., Kucera R., Kacerovsky M., Tebbens J. D., Bonnin A., Abad C., Staud F. Serotonin homeostasis in the materno-foetal interface at term: Role of transporters (SERT/SLC6A4 and OCT3/SLC22A3) and monoamine oxidase A (MAO-A) in uptake and degradation of serotonin by human and rat term placenta. Acta Physiologica. 2020; 229(4): 1-16. (IF2019=5.542)
Juhás M., Kučerová M., Horáček O., Janďourek O., Kubíček V., Konečná K., Kučera R., Bárta P., Janoušek J., Paterová P., Kuneš J., Doležal M., Zitko J. N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents-The Synthesis and Biological Evaluation of Enantiomers. Molecules. 2020; 25(7): 1-29. (IF2019=3.267)
Demuth J., Miletin M., Kucera R., Ruzicka A., Havlinova Z., Libra A., Novakova V., Zimcik P. Self-assembly of azaphthalocyanine-oligodeoxynucleotide conjugates into J-dimers: towards biomolecular logic gates. Organic Chemistry Frontiers. 2020; 7: 445-456. (IF2019=5.155)
Herman D., Dlabkova A., Cechova L., Vanova N., Misik J., Jun D., Zdarova-Karasova J. Simple validated method of LC–MS/MS determination of BZ agent in rat plasma samples. Drug Testing and Analysis. 2020; 1-8. (IF2019=2.903)
2019
Maly O., Zajak J., Hyspler R., Turek Z., Astapenko D., Jun D., Vanova N., Kohout A., Radochova V., Kotek J., Paral J. Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection. Annals of Translational Medicine. 2019; 7(23): 774-774. (IF2019=3.297)
Valis M., Herman D., Vanova N., Masopust J., Vysata O., Pavelek Z., Hort J., Klimova B., Kuca K., Misik J., Zdarova-Karasova J. The concentration of memantine in the cerebrospinal fluid of patients with Alzheimer´ s disease and its consequence to oxidative stress biomarkers. Frontiers in Pharmacology. 2019; 10(943): 1-8. (IF2019=4.225)
Lochman L., Machacek M., Miletin M., Uhlířová Š., Lang K., Kirakci K., Zimcik P., Novakova V. Red-Emitting Fluorescence Sensors for Metal Cations: The Role of Counteranions and Sensing of SCN− in Biological Materials. ACS Sensors. 2019; 4(6): 1552-1559. (IF2019=7.333)
Kollar J., Machacek M., Jancarova A., Kubat P., Kucera R., Miletin M., Novakova V., Zimcik P. Effect of bovine serum albumin on the photodynamic activity of sulfonated tetrapyrazinoporphyrazine. Dyes and Pigments. 2019; 162: 358-366. (IF2019= 4.613)
Reimerová P., Stariat J., Bavlovič Piskáčková H., Jansová H., Roh J., Kalinowski D.S., Macháček M., Šimůnek T., Richardson D.R., Štěrbová-Kovaříková P. Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials. Analytical and Bioanalytical Chemistry. 2019; 411(11): 2383-2394. (IF2019=3.637)
Reimerová P., Jirkovská A., Bavlovič Piskáčkova H., Karabanovich G., Roh J., Šimůnek T., Štěrbová-Kovaříková P. UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study. Scientific Reports. 2019; 9(1); 4524: 1-12. (IF2019=3.998)
Patents
Kapkowski, M.; Ludynia, M.; Polański, J.; Rudnicka, M.; Dzida, M.; Balin, K.; Doležal, M.; Kastner, P. Kompozycja poprawiająca penetrację substancji biologicznie aktywnych przez powierzchnie organów roślinnych. Zgloszenie patentowe, P.430248; 02-07-2019
Kapkowski, M.; Ludynia, M.; Polański, J.; Rudnicka, M.; Dzida, M.; Balin, K.; Doležal, M.; Kastner, P. Směs usnadňující penetraci biologicky aktivních látek povrchem do rostlinných orgánů. Přihláška českého patentu PV 2019-614; 02-10-2019
2018
Jansová H., Kubeš J., Reimerová P., Štěrbová-Kovaříková P., Roh J., Šimůnek T. 2,6-Dihydroxybenzaldehyde Analogues of the Iron Chelator Salicylaldehyde Isonicotinoyl Hydrazone: Increased Hydrolytic Stability and Cytoprotective Activity against Oxidative Stress. Chemical Research in Toxicology. 2018; 31(11): 1151-1163. (IF2018=3.274)
Hrušková K., Potůčková E., Opálka L., Hergeselová T., Hašková P., Kovaříková P., Šimůnek T., Vávrová K. Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities. Chemical Research in Toxicology. 2018; 31(6): 435-446. (IF2018=3.274)
Sorf A., Hofman J., Kučera R., Staud F., Ceckova M. Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro. Biochemical Pharmacology. 2018; 154: 10-17. (IF2018=4.825)
Demuth J., Kučera R., Kopecky K., Havlinova Z., Libra A., Novakova V., Miletin M., Zimcik P. Efficient Synthesis of a Wide-Range Absorbing Azaphthalocyanine Dark Quencher and Its Application to Dual-Labeled Oligonucleotide Probes for Quantitative Real-Time Polymerase Chain Reactions. Chemistry-A European Journal. 2018; 24(38): 9658-9666. (IF2018=5.160)
Jirkovsky E., Jirkovska A., Bures J., Chladek J., Lencova O., Stariat J., Pokorna Z., Karabanovich G., Roh J., Brazdova P., Simunek T., Kovarikova P., Sterba M. Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart. Journal of Pharmacology and Experimental Therapeutics. 2018, 364 (3) 433-446. (IF2018=3.615)
2017
Bouz G., Juhás M., Niklová P., Jamďourek O., Paterová P., Janoušek J., Tůmová L., Kovalíková Z., Kastner P., Doležal M., Zitko J. Ureidopyrazine Derivatives: Synthesis and Biological Evaluation as Anti-Infectives and Abiotic Elicitors. Molecules. 2017; 23(10); 1797: 1-16. (IF2017=3.098) DOI: 10.3390/molecules22101797
Květina J., Tacheci I., Nobilis M., Kopáčová M., Kuneš M., Bureš J. The Importance of Wireless Capsule Endoscopy for Research into the Intestin Absorption Window of 5-Aminosalicylic Acid in Experimental Pig. Current Pharmaceutical Design. 2017; 23(12):1873-1876,
(IF2017 = 2.611) DOI: 10.2174/1381612822666161201145247
Nejedly T., Klimes J. A model of natural degradation of 17-alpha-ethinylestradiol in surface water and identification of degradation products by GC-MS. Environmental science and pollution Research. 2017; 24: 23196-23206 (IF2017=2.800)
Bures J., Jirkovska A., Sestak V., Jansova H., Karabanovich G., Roh J., Sterba M., Simunek T., Kovarikova P. Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite. Toxicology. 2017; 392:1-10. (IF2017=3.265)
Kastner P., Pilařová P., Nejedlý T., Macháček M., Klimeš J. Stability Indicating Method for Determination of Sodium Picosulfate in Pharmaceutical Preparation – Comparison of HPLC, UHPLC and HTLC, Current Pharmaceutical Analysis, 2017; 13(3): 250-255 (IF2017 = 0.859) DOI: 10.2174/1573412912666160518145632
2016
Lenčová-Popelová O., Jansová H., Jirkovský E., Bureš J., Jirkovská-Vávrová A., Mazurová Y., Reimerová P., Vostatková L., Adamcová M., Hroch M., Pokorná Z., Kovaříková P. Šimůnek T, Štěrba M. Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings? Toxicology. 2016; 372:52-63. (IF2016=3.528)
Hašková P., Jansová H., Bureš J., Macháček M., Jirkovská A., Franz K.J., Kovaříková P., Šimůnek T. Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. Toxicology. 2016; 371:17-28. (IF2016=3.528)
Snejdrova E., Drastik M ., Dittrich M., Kastner P., Nguyenova J. Mucoadhesive plasticized system of branched poly(lactic-co-glycolic acid) with aciclovir. Drug Development and Industrial Pharmacy. 2016; 42; 1653-9 (IF2016=2.429)
Tycova A., Vido M., Kovarikova P., Foret F. Interface-free capillary electrophoresis-mass spectrometry system with nanospray ionization-Analysis of dexrazoxane in blood plasma, Journal of Chromatography A. 2016; 1466: 173-179. (IF2016=3.981)
Hrušková K., Potůčková E., Hergeselová T., Liptáková L., Hašková P., Mingas P., Kovaříková P., Šimůnek T., Vávrová K. Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications, European Journal of Medicinal Chemistry. 2016; 120:97-110 (IF2016=4.519)
Jansová H., Bureš J., Macháček M., Hašková P., Jirkovská A., Roh J., Wang Q., Franz K.J., Kovaříková P., Šimůnek T. Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products, Toxicology. 2016; 350-352:15-24 (IF2016=3.528)
Macháček, M., Kollár, J., Miletin M., Kučera R., Kubat, P., Šimůnek T., Nováková V., Zimčík P. Anionic hexadeca-carboxylate tetrapyrazinoporphyrazine: synthesis and in vitro photodynamic studies of a water-soluble, non-aggregating photosensitizer, RSC Advances. 2016; 6(12): 10064-10077. (IF2016= 3.108)
Sestak V., Roh J., Klepalova L., Kovarikova P. A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor, Journal of Pharmaceutical and Biomedical Analysis. 2016; 124: 365-73 (IF2016=3.255)
Klivický M., Klimeš J., Kučera R. Solid-Phase Extraction of Ibuprofen from Pharmaceuticals via Ligand Exchange Using Zirconium Dioxide, Current Analytical Chemistry. 2016; 12(6): 523-528. (IF2016 = 1.306)
Hofman, J., Kučera, R., Neumanova, Z., Klimeš, J., Ceckova, M., Staud, F. Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs), Xenobiotica. 2016; 46(5): 416-423. (IF2016= 1.932)
2015
Kastner P., Burdová K., Pilařová P. HPLC method for stability evaluation of pharmaceutical preparations containing sodium picosulfate, Česká a slovenská farmacie. 2015; 64: 215.
Suchá L., Kolenič M., Kratochvíl J., Pour M., Nobilis M., Čermáková E., Řezáčová M., Tomšík P. Novel derivatives of benfluron and dimefluron: synthesis and anticancer activity. Letters in Drug Design&Discovery. 2015; 12(10): 787-801. (IF2014= 0.770)
Šesták V., Stariat J., Cermanová J., Potůčková E., Chládek J., Roh J., Bureš J., Jansová H., Průša P., Stěrba M., Mičuda S., Šimůnek T., Kalinowski D. S., Richardson D.R., Kovaříková R. Novel and Potent Anti-Tumor and Anti-Metastatic Di-2-Pyridylketone Thiosemicarbazones Demonstrate Marked Differences in Pharmacology Between the First and Second Generation Lead Agents, Oncotarget. 2015; 6(40): 42411-42428 (IF2015= 5.008)
Potůčková E., Roh J., Macháček M., Sahni S., Stariat J., Šesták V., Jansová H., Hašková P., Jirkovská A., Vávrová K., Kovaříková P., Kalinowski D. S., Richardson D. R., Šimůnek T. In vitro characterization of the pharmacological properties of the anti-cancer chelator, Bp4eT, and ts phase I metabolites, PLoS ONE. 2015; 10(10): e0139929. doi:10.1371/journal.pone.0139929 (IF2015=3.007)
Cihalova, D., Ceckova, M., Kučera, R., Klimeš, J., Staud, F. Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro. Biochemical Pharmacology. 2015; 98(3): 465-472. (IF2015= 5.091)
Vachova, L., Machacek, M., Kučera, R., Demuth, J.; Cermak, P., Kopecky, K., Miletin, M., Jedlickova, A., Simunek, T., Novakova, V., Zimcik, P. Heteroatom-substituted tetra(3,4-pyrido)porphyrazines: a stride toward near- infrared-absorbing macrocycles. Organic & Biomolecular Chemistry. 2015; 13(20): 5608-5612. (IF2015=3.559)
Macháček, M., Cidlina A., Nováková V., Švec J., Rudof E., Miletin M., Kučera R., Šimůnek T., Zimčík P. Far-Red-Absorbing Cationic Phthalocyanine Photosensitizers: Synthesis and Evaluation of the Photodynamic Anticancer Activity and the Mode of Cell Death Induction. Journal of Medicinal Chemistry. 2015; 58(4): 1736-1749. (IF2015= 5.589)
Bureš J., Jansová H., Stariat J., Filipský T., Mladěnka P., Šimůnek T., Kučera R., Klimeš J., Wang Q., Franz K.J., Kovaříková P. LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). Journal of Pharmaceutical and Biomedical Analysis. 2015; 105(1): 55-63. (IF2014= 2.979)
Servusova-Vanaskova, B., Jandourek, O., Paterova, P., Kordulakova, J., Plevakova, M., Kubicek, V., Kučera, R., Garaj, V., Naesens, L., Kunes, J., Dolezal, M., Zitko, J. Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation. Medchemcomm. 2015; 6(7): 1311-1317. (IF2015= 2.319)
2014
Potůčková E., Hrušková K., Bureš J., Kovaříková P., Špirková I.A., Pravdíková K., Kolbabová L., Hergeselová T., Hašková .P, Jansová H, Macháček M., Jirkovská A., Richardson V., Lane D.J., Kalinowski D.S., Richardson D.R., Vávrová K., Šimůnek T. Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties. PLoS One. 2014, 9(11): e112059. (IF2014= 3.234)
Cermanova J., Kadova Z., Dolezelova E., Zagorova M., Safka V., Hroch M., Laho T., Holeckova M., Mokry J., Kovarikova P., Bures J., Sterba M., Micuda S. Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats. Shock. 2014, 42(4):372-79. (IF2014= 3.045)
Kučera R., Kovaříková P., Pasáková-Vrbatová .I, Slaninová J., Klimeš J. Zirconia-a stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography. Journal of Separation Science. 2014, 37(9-10):1089-93. (IF2014= 2.737)
Servusová-Vanasková, B., Paterová, P., Mandikova, J., Plevakova, M., Kubicek, V., Kučera, R., Kunes, J., Dolezal, M., Zitko, J. Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation. Bioorganic & Medicinal Chemistry Letters. 2014; 24(2): 450-453. (IF2014= 2.420)
Stariat J., Suprunová V., Roh J., Šesták V., Eisner T., Filipský T., Mladěnka P., Nobilis M., Šimůnek T., Klimeš J., Kalinowski D.S., Richardson D.R., Kovaříková P. Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats. Biomedical Chromatography. 2014; 28(5): 621-629.. (IF2014= 1.723)
Česlová L., Holčapek M., Nobilis M. Identification of combined conjugation of nabumetone phase I metabolites with glucuronic acid and glycine in minipig biotransformation using coupling high-performance liquid chromatography with electrospray ionization mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis. 2014; 88: 221-224. (IF2014=2.979)
2013
Hofman J., Kucera R., Cihalova D., Klimes J., Ceckova M., Staud F. Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1), Plos one. 2013; 8(10). (IF2013=3.534)
Škarydová L., Nobilis M., Wsól V. Role of carbonyl reducing enzymes in the phase I biotransformation of the NSAID nabumetone in vitro, Xenobiotica. 2013; 43(4):346-354. (IF2013=2.101)
Zitko, J., Servusová, B., Paterová, P., Mandikova, J., Kubicek, V., Kučera, R., Hrabcova, V., Kunes, J., Soukup, O., Dolezal, M., Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides, Molecules. 2013; 18(12): 14807-14825. (IF2013=2.095)
Smetanová L., Štětinová V., Kholová D., Kuneš M., Nobilis M., Svoboda Z., Květina J. Transintestinal transport mechanisms of 5-aminosalicylic acid (in situ rat intestine perfusion, Caco-2 cells) and Biopharmaceutics Classification System, General Physiology and Biophysics. 2013; 32(3):361-369. (IF2013=0.875)
Nobilis M., Mikušek J., Szotáková B., Jirásko R., Holčapek M., Chamseddin C., Jira Th., Kučera R., Kuneš J., Pour M. Analytical power of LLE-HPLC-PDA-MS/MS in drug metabolism studies: Identification of new nabumetobe metabolites, Journal of Pharmaceutical and Biomedical Analysis. 2013; 80:164-172. (IF2013=2.829)
Pilařová P., Kastner P., Nejedlý T., Klimeš J. Development and validation of rapid UHPLC method for determination of aciclovir, its impurities and preservatives in topical cream, Analytical Methods. 2013; 5(10):2610-14. (IF2013= 1.938)
Opletalová V., Kastner P., Kučerová-Chlupáčová M., Palát K. Study of hydrophobic properties of biologically active open analogues of flavonoids, Journal of Molecular Graphics & Modelling. 2013; 39:61–64. (IF2013= 2.022)
Cahlikova L., Locarek M., Benesova N., Kucera R., Chlebek J., Novak Z., Opletal L. Isolation and Cholinesterase Inhibitory Activity of Narcissus Extracts and Amaryllidaceae Alkaloid, Natural Product Communications. 2013; 8(6):781-785. (IF2013= 0.924)
Pilařová P. Kastner P., Klimeš J. Determination of Amphetamine and Methamphetamine And Their 4-Hydroxy Derivatives by HPLC with Fluorescence Detection, Chemické Listy. 2013; 107(1): 58-61. (IF2013 = 0,196)
Stariat J., Kovaříková P., Kučera R., Klimeš J., Kalinowski D.S, Richardson D.R, Ketola R.A. Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry, Analytical and Bioanalytical Chemistry. 2013; 405(5):1651-61. (IF2013= 3.578)
Kovaříková P., Pasaková-Vrbatová I., Vávrová A., Stariat J., Klimeš J., Simunek T. Development of LC–MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium, Journal of Pharmaceutical and Biomedical Analysis .2013; 76(1): 243-51. (IF2012= 2.829)
Štěrba M., Popelová O., Vávrová A., Jirkovský E., Kovaříková P., Geršl V., Šimůnek T. Oxidative stress, redox signaling and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection, Antioxidants & Redox Signaling. 2013;18(8): 899-929. (IF2013: 7.667)
2012
Kalafut P., Kučera R., Klimeš J. The Retention Behavior of Acidic, Basic and Neutral Pharmaceuticals on the Deactivated Polybutadiene Zirconia Phase, Current Analytical Chemistry. 2012; 8(4): 574-582. (IF2012: 1.558)
Kalafut P., Kučera R., Klimeš J. The influence of a carbon layer deposited on a zirconia surface on the retention of polar analytes in an organic rich mobile phase , Journal of Chromatography A. 2012; 1232 : 242-247. (IF2012: 4.612)
Cahlíková L., Kučera R., Hošťálková, A.,Klimeš J., Opletal L. Identification of Pavinane Alkaloids in the Genera Argemone and Eschscholzia by GC-MS Natural Product Communications. 2012; 7(10): 1279-1281. (IF2012: 0.956)
Cahlíková L., Benešová N., Macáková K., Kučera R., Hrstka V., Klimeš J., Jahodář L., Opletal L. Alkaloids from some amaryllidaceae species and their cholinesterase activity, Natural Product Communications. 2012; 7(5): 571-574. (IF2012: 0.956)
Novakova V., Kobak R.Z.U., Kučera R., Kopecky K., Miletin M., Krepsová V., Ivincová J., Zimcik P. The effect of the number of carbohydrate moieties on the azaphthalocyanine properties, Dalton Transactions. 2012; 41: 10596-10604. (IF2012: 3.806)
Macková E., Hrušková K., Bendová P., Vávrová A., Jansová H., Hašková P., Kovaříková P., Vávrová K., Šimůnek T. Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action, Chemico-Biological Interactions. 2012; 197: 69-79. (IF2012: 2.967)
Stariat J., Šesták V., Vávrová K., Nobilis M., Kollárová Z., Klimeš J., Kalinowski D.S., Richardson D.R., Kovaříková P. LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT, Analytical and Bioanalytical Chemistry. 2012; 403(1): 309-321. (IF2012= 3.659)
Hroch M., Havlinova Z., Nobilis M., et al. HPLC determination of arginases inhibitor N-(omega)-hydroxy-nor-L-arginine using core-shell particle column and LC-MS/MS identification of principal metabolite in rat plasma, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences.2012; (880): 90-99. (IF2012: 2.487)
2011
Kučera R., Kovaříková P., Klivický M., Klimeš J. The retention behaviour of polar compounds on zirconia based stationary phases under hydrophilic interaction liquid chromatography conditions, Journal of Chromatography A. 2011; 1218(39): 6981-6986. (IF2011: 4.531)
Kopecky K., Novakova V., Miletin M., Kučera R., Zimcik P. Synthesis of new azaphthalocyanine dark quencher and evaluation of its quenching efficiency with different fluorophores, Tetrahedron. 2011; 67(33): 5956-5963. (IF2011: 3.025)
Zítko J., Doležal M., Svobodová M., Vejsová M., Kuneš J., Kučera R., Jílek P. Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides, Bioorganic & Medicinal Chemisty. 2011; 19(4): 1471-1476. (IF2011: 2.921)
Vávrová K., Kovaříková P., Školová B., Líbalová M., Roh J., Čáp R., Holý A., Hrabálek A. Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP, Pharmaceutical Research. 2011; 28(12): 3105-3115. (IF2011: 4.093)
Hašková P., Koubková L., Vávrová A., Macková E., Hrušková K., Kovaříková P., Vávrová K., Šimůnek T. Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity, Toxicology. 2011; 289(2-3): 122-131. (IF2011: 3.681)
Pasáková I., Gladziszová M., Charvátová J., Stariat J., Klimeš J., Kovaříková P. Use of different stationary phases for separation of isoniazid, its metabolites and vitamin B6 forms, Journal of Separation Science. 2011; 34(12): 1357-1365. (IF2011: 2.733)
Hrušková K., Kovaříková P., Bendová P., Hašková P., Macková E., Stariat J., Vávrová A., Vávrová K., Šimůnek T. Synthesis and initial in vitro evaluations of novel antioxidant aroylhydrazone iron chelators with increased stability against plasma hydrolysis, Chemical Research in Toxicology. 2011; 24(3): 290-302. (IF2011: 3.779)
Hašková P., Kovaříková P., Koubková L., Vávrová A., Macková E., Šimůnek T. Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autooxidation and cardiotoxicity, Free Radical Biology and Medicine. 2011; 50(4): 537-549. (IF2011: 5.423)
Kovaříková P., Stariat J., Klimeš J., Hrušková K., Vávrová K. Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case, Journal of Chromatography A. 2011; 1218(3): 416-426. (IF2011: 4.531)
Nobilis M., Vybiralova Z., Szotakova B., et al. High-performance liquid chromatographic determination of tiapride and its phase I metabolite in blood plasma using tandem UV photodiode-array and fluorescence detection, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences.2011; 879(32): 3845-3852.(IF2011: 2.888)
Jirasko R., Holcapek M., Nobilis M. Identification of phase I and phase II metabolites of benfluron and dimefluron in rat urine using high-performance liquid chromatography/tandem mass spectrometry, Rapid Communications in Mass Spectrometry. 2011; 25(15): 2153-2162. (IF2011: 2.790)
2010
Kopecky K., Novakova V., Miletin M., Kučera R., Zimcik P. Solid-Phase Synthesis of Azaphthalocyanine-Oligonucleotide Conjugates and Their Evaluation As New Dark Quenchers of Fluorescence, Bioconjugate Chemistry. 2010; 21(10): 1872-1879. (IF2010: 5.002)
Bendová P., Macková E., Hašková P., Vávrová A., Jirkovský E., Šterba M., Popelová O., Kalinowski D.S, Kovaříková P., Vávrová K., Richardson D.R, Šimůnek T. Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury, Chemical Research in Toxicology. 2010; 23(6): 1105-1114. (IF2010: 4.140)
Stariat J., Kovaříková P., Klimeš J., Kalinowski D.S., Richardson D.R. Development of an LC-MS/MS method for analysis of interconvertible Z/E Isomers of novel anti-cancer agent, Bp4eT, Analytical and Bioanalytical Chemistry. 2010; 397(1): 161-171. (IF2010: 3.841)
Mokry M., Klimes J., Pechova J. HPLC analysis of syrup containing nimesulide and its hydrolytic degradation product, Chemical Papers. 2010; (64): 405-408. (IF2010: 0.754)
Senel P., Tichotova L., Votruba I., Nobilis. M., et al. Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives, Bioorganic & Medicinal Chemistry. 2010; 18(5): 1988-2000. (IF2010: 2.978)
2009
Kalafut P., Kučera R., Klimeš J., Sochor J. An innovative approach to the analysis of 3-[4-(2-methylpropyl)phenyl]propanoic acid as an impurity of ibuprofen on a carbon-coated zirconia stationary phase, Journal of Pharmaceutical and Biomedical Analysis. 2009; 49(5): 1150- 1156. (IF2009: 2.453)
Žižkovský V., Kučera R., Klimeš J., Holásková P. Dohnal J. RP-ZrO2 stationary phase as an alternative to separate of doxazosin impurities, Chromatographia. 2009; 70(1-2): 185-189. (IF2009: 1.098)
Pasáková I., Kovaříková P., Kučera R., Klimeš J., Sochor J., Hrábalek A. Development and validation of an LC-ESI-MS ion-trap method for analysis of impurities in Transkarbam 12, a novel transdermal accelerant, Chromatographia. 2009; 96(9-10): 977 – 983. (IF2009: 1.098)
Novotný J., Kovaříková P., Novotný M., Janušová B., Hrabálek A., Vávrová K. Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: Effects of linking chain length, chirality and polyfluorination, Pharmaceutical Research. 2009; 26(4): 811 – 821. (IF2009: 3.933)
Stariat J., Kovaříková P., Klimeš J., Lovejoy D.B., Kalinowski D.S., Richardson D.R. HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents, Journal of Chromatography . 2009; 877(3): 316 – 322. (IF2009: 2.777)
Krizova V., Nobilis M., Pruskova L., et al. Pharmacokinetics of flubendazole and its metabolites in lambs and adult sheep (Ovis aries), Journal Of Veterinary Pharmacology And Therapeutics. 2009; 32(6): 606-612. (IF2009: 1.408)
2008
Žižkovský V., Kučera R., Klimeš J., Dohnal J. Titania-based stationary phase in separation of ondansetron and its related compounds, Journal of Chromatography A. 2008; 1189(1-2): 83-91. (IF2008: 3.756)
Kovaříková P., Vávrová K., Tomalová K., Schöngut M., Hrušková K., Hašková P. Klimeš J. HPLC-DAD and MS/MS analysis of novel drug candidates from the group of aromatic hydrazones revealing the presence of geometric isomers, Journal of Pharmaceutical and Biomedical Analysis. 2008; 48(2): 295 - 302. (IF2008: 2.629)
Mrkvičková Z., Kovaříková P., Balíková S., Klimeš J. Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations, Journal of Pharmaceutical and Biomedical Analysi. 2008; 48(2): 310 - 314. (IF2008: 2.629)
Kovaříková P., Mrkvičková Z., Klimeš J. Investigation of the stability of aromatic hydrazones in plasma and related biological material, Journal of Pharmaceutical and Biomedical Analysis. 2008; 47(2): 360 – 370. (IF2008: 2.629)
Nobilis M., Vybiralova Z., Krizova V., et al. Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection Application to pharmacokinetic studies in sheep, Journal of Chromatography B-Analytical Technologies in The Biomedical and Life Sciences. 2008; 876(1): 89-96. (IF2008: 2.500)
Kubicek V., Soukupova M., Nobilis M., et al. LC with Fluorimetric Detection for Sensitive Analysis of Reduced Flubendazole in Biological Samples, Chromatographia. 2008; 68( 9-10): 865-867. (IF2008: 1.312)
Holcapek M., Kolarova L., Nobilis M. High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites, Analytical and Bioanalytical Chemistry. 2008; 391(1): 59-78.. (IF2008: 3.328)
Cvilink V., Kubicek V., Nobilis M., et al. Biotransfonnation of flubendazole and selected model xenobiotics in Haemonchus contortus, Veterinary Parasitology. 2008; 151(2-4): 242-248. (IF2008: 2.039)
Pilarova P., Kastner P., Klimes J. Isolation and Identification of Amphetamines in Urine by Thin-Layer Chromatography, Jpc-Journal of Planar Chromatography-Modern Tlc. 2008; 21(6): 465-468. (IF2008: 0.982)
2007
Zerzaňová A., Žižkovský V., Kučera, R., Klimeš J., Jesenský I., Dohnal J., Barrón D. Using of HPLC coupled with coulometric detector for the determination of biotin in pharmaceuticals, Journal of Pharmaceutical and Biomedical Analysis. 2007; 45(5): 730-735. (IF2007: 2.761)
Žižkovský V., Kučera R., Klimeš J., Dohnal J. Potential employment of non-silica-based stationary phases in pharmaceutical analysis, Journal of Pharmaceutical and Biomedical Analysis. 2007; 44(5): 1048-1055. (IF2007: 2.761)
Malakova J., Nobilis M., Svoboda Z., Lisa M., Holcapek M., Kvetina J., Klimes J., Palicka V. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples, Journal Of Chromatography B-Analytical Technologies In The Biomedical And Life Sciences. 2007; 853(1-2): 265-274. (IF2007: 2.935)
Nobilis M., Pour M., Senel P., et al. Metabolic profiling of a potential antifungal drug, 3-(4-bromophenyl)-5-acetoxymethyl-2,5-dihydrofuran-2-one, in mouse urine using high-performance liquid chromatography with UV photodiode-array and mass spectrometric detection, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2007; 853(1-2): 10-19. (IF2007: 2.935)
Nobilis M., Jira T., Lisa M., et al. Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection, Journal of Chromatography A .2007; 1149 (1): 112-120. (IF2007: 3.641)
Slanar O., Nobilis M., Kvetina J., et al. Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T, European Journal of Clinical Pharmacology. 2007; 63(4): 419-421. (IF2007: 2.177)
Slanar O., Nobilis M., Kvetina J., et al. Miotic action of tramadol is determined by CYP2D6 genotype, Physiological Research. 2007; 56(1): 129-136. (IF2007: 1.505)
Mrkvičková Z., Kovaříková P., Klimeš J., Kalinowski D., Richardson D.R. Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity, Journal of Pharmaceutical and Biomedical Analysis. 2007; 43(4): 1343 - 1351. (IF2007: 2.761)
2006
Garcés A., Zerzaňová A., Kučera, R., Barrón, D., Barbosa, J. Determination of a series of quinolones in pig plasma using solid-phase extraction and liquid chromatography coupled with mass spectrometric detection. Application to pharmacokinetic studies, Journal of Chromatography A. 2006; 1137(1): 22-29. (IF2006: 3.554)
Mrkvičková Z., Kovaříková P., Klimeš J., Doležal M. Determination of the lipophilicity of potential antituberculotic compounds by RP-TLC, Journal of Planar Chromatography. 2006; 19(112): 422 - 426. (IF2006: 1.153)
Kovaříková P., Klimeš J., Štěrba M., Popelová O., Geršl V., Poňk, P. HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study, Journal of Chromatography B. 2006; 838(2): 107 - 112. (IF2006: 2.647)
Kovaříková P., Mokrý M., Klimeš J., Vávrová K. HPLC study on stability of pyridoxal isonicotinoyl hydrazone, Journal of Pharmaceutical and Biomedical Analysis. 2006; 40(1): 105 - 112. (IF2006: 2.032)
Pasakova I., Klimes J., Sochor J., Hrabalek A. Optimization of HPLC chromatographic conditions for determination of Transkarbam 12 and its degradation products, Journal of Pharmaceutical and Biomedical Analysis.2006; 42(1): 136-142. (IF2006: 2.032)
Pasakova I., Sochor J., Klimes J.,Hrabalek A. Preliminary pharmaceutico-analytical evaluation of Transkarbam 12 using liquid chromatography, Journal of Separation Science. 2006; 29(11): 1595-1599. (IF2006: 2.535)
Kresta J., Kastner P., Klimes J., Klimesova J. Reversed-phase thin-layer chromatographic determination of the lipophilicity of potential antituberculotic compounds, Jpc-Journal of Planar Chromatography-Modern Tlc. 2006; 18(106): 450-454. (IF2006: 1.153)
Zerzanova A., Cisar P., Klimes J. Comparison of different stationary phases for bioanalytical studies of biologically active compounds, Journal of Separation Science.2006; (29): 2126–2135. (IF2006: 2.535)
Nobilis M., Vybiralova Z., Sladkova K., et al. High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma, Journal of Chromatography A.2006; 1119 (1-2): 299-308. (IF2006: 3.554)
2005
R. Kučera, V. Žižkovský, J. Sochor, J. Klimeš, J. Dohnal. Utilization of zirconia stationary phase as a tool in drug control, Journal of Separation Science. 2005; 28: 1307-1314. (IF2005: 1.829)
R. Kučera, J. Sochor, J. Klimeš, J. Dohnal. Use of the zirconia-based stationary phase for separation of ibuprofen and its impurities, Journal of Pharmaceutical and Biomedical Analysis. 2005; 38: 609-618. (IF2005: 1.889)
Kučera R., Nobilis M., Skálová L., Szotáková B., Císař P., Jira Th., Klimeš J., Wsól V. Use of chiral reversed-phase liquid chromatography for the evaluation of stereoselectivity in the karbonyl reduction of potential benzo(c)fluorene antineoplastics benfluron in various species, Journal of Pharmaceutical and Biomedical Analysis. 2005; 37: 1049-1057. (IF2005: 1.889)
Kovaříková P., Klimeš J., Štěrba M. Popelová O., Mokrý M., Geršl V., Poňka P. Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study, Journal of Separation Science. 2005; 28(12): 1300 - 1306. (IF2005: 1.829)
Hanysova L., Vaclavkova M., Dohnal J., Klimes J.Stability of ramipril in the solvents of different pH, Journal of Pharmaceutical and Biomedical Analysis. 2005; (37): 1179–1183. (IF2005: 1.889)
Cisar P., Nobilis M., Vybiralova Z., et al. Disposition study of a new potential antineoplastic agent dimefluron in rats using high-performance liquid chromatography with ultraviolet and mass spectrometric detection, Journal of Pharmaceutical and Biomedical Analysis.2005; 37(5): 1059-107. (IF2005: 1.889)
Hanysova L., Mokry M., Kastner P., et al. HPLC evaluation of diclofenac in the various forms of therapeutic preparations, Chemical Papers. 2005; 59(2): 103-108. (IF2005: 0.409)
Hanysova L., Kastner P., Klimes J. Degradation products and impurities of paracetamol from viewpoint of analytical detection, Chemicke Listy. 2005; 99(9): 647-652. (IF2005: 0.445)
Vybiralova Z., Nobilis M., Zoulova J., et al. High-performance liquid chromatographic determination of ciprofloxacin in plasma samples, Journal of Pharmaceutical and Biomedical Analysis. 2005; 37(5): 851-858. (IF2005: 1.889)