Research focus
Education and professional carrier
Grant projects
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2014 – 2016 Grant Agency of Charles University: Study of recognition moieties of sensoric azaphthalocyanines. GAUK: 494214 (principal investigator)
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2014 – 2016 Czech Science Foundation: Development of new photosensitizers for photodynamic therapy and investigation of their mechanism of action on cellular level. GAČR: 13-27761S (co-worker)
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Since 2014: Co-worker of several other grants: Grant Agency of Charles University (GAUK: 1182313; GAUK: 1916214).
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2013 – 2017 Charles University: UNCE project Centre for investigation of toxic and protective effects of drugs on cardiovascular system.‘‘ UNCE 33/2012 (co-worker)
Professional membership
Educational activities
- 2020 Centre for Lifelong Learning (Charles University): Educational program of pedagogical skills.
- 2021 Centre for Lifelong Learning (Charles University): Management skills development program.
Awards/Prizes
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2019 - Faculty medal - The medal of the Faculty of Pharmacy for excellent scientific results and faculty development
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2019 - Bolzano Award (University Award) in biomedical disciplines category
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2018 - Josef Hlavka Award for the Best Students and Graduates
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2017 - 2nd place in the prestigious competition Sanofi Prize for Pharmacy 2017 arranged by French Embassy in the Czech Republic and Jean-Marie Lehn (laureate of Nobel Prize)
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2017 - Medal of the City of Hradec Kralove for scientific work
Research fellowship
- 2019 - Institut Charles Sadron CNRS, University of Strasbourg (Strasbourg, France) – Layer-by-layer assembly technique for capillary wall modification usable in separation aplications. Prof. Gero Decher (3 months)
- 2016 - Graz University of Technology (Graz, Austria) – The study of possibility to use azaphthalocyanine indicators in CO2 sensors. Ass. Prof. Sergey Borisov (1 month)
- 2015 - Graz University of Technology (Graz, Austria) – The application of azaphthalocyanine indicators in fluorescent sensors for metal cations. Ass. Prof. Sergey Borisov (3 months)
Publications
Journals with impact factor (∑IF = 40.545; ØIF = 5.792):
- Pavek P, Dusek J, Smutny T, Lochman L, Kucera R, Skoda J, Smutna L, Kamaraj R, Soucek P, Vrzal R, Dvorak Z. Gene Expression Profiling of 1α,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes. Molecular Nutrition and Food Research. 2022; 2200070: 1-17. (IF2021 = 6.575; AIS: 1,009)
- Horáček O, Papajová-Janetková M, Grüner B, Lochman L, Štěrbová-Kovaříková P, Vespalec R, Kučera R. The first chiral HPLC separation of dicarba-nido-undecarborate anions and their chromatographic behavior. Talanta. 2021; 222: 1-9. (IF2020 = 6.057; AIS: 0.828)
- Lochman L, Machacek M, Miletin M, Uhlířová Š, Lang K, Kirakci K, Zimcik P, Novakova V. Red-Emitting Fluorescence Sensors for Metal Cations: The Role of Counteranions and Sensing of SCN− in Biological Materials. ACS Sensors. 2019; 4 (6): 1552-1559. (IF2018 = 6.944; AIS: 1.462)
- Lochman L, Zimcik P, Klimant I, Novakova V, Borisov SM. Red-emitting CO2 sensors with tunable dynamic range based on pH-sensitive azaphthalocyanine indicators. Sensors and Actuators B: Chemical. 2017; 246: 1100-1107. (IF2016 = 5.401; AIS: 0.786)
- Lochman L, Svec J, Roh J, Kirakci K, Lang K., Zimcik P, Novakova V. Metal cation recognition in water by a tetrapyrazinoporphyrazine-based tweezer receptor. Chemistry - A European Journal. 2016; 22 (7): 2417-2426. (IF2015 = 5.771; AIS: 1.407)
- Lochman L, Svec J, Roh J, Novakova V. The role of the size of aza-crown recognition moiety in azaphthalocyanine fluorescence sensors for alkali and alkaline earth metal cations. Dyes and Pigments. 2015; 121: 178-187. (IF2014 = 3.966; AIS: 0.629)
- Novakova V, Lochman L, Zajícová I, Kopecky K, Miletin M, Lang K, Kirakci K, Zimcik P. Azaphthalocyanines: Red Fluorescent probes for Cations. Chemistry - A European Journal. 2013; 19 (16): 5025-5028. (IF2012 = 5.831; AIS: 1.478)