The research group focuses on a wide range of aspects concerning phthalocyanines and, in particular, azaphthalocyanines. Synthetic approaches, photophysical and photochemical behavior are studied in several applications. Within this group, the PRIMUS team was established in January 2020 as a subgroup led by Veronika Novakova. This team focuses on synthesis, photophysical study and biological evaluation of selected macrocycles requiring demanding synthesis. For the team members see section People.
News
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December 2021: a new PhD student, Mary Angelia Alfred, just joined our team. Welcome!
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July 2021: Our posdoc, great researcher and good friend Rahul Kaushik left our group because he received the Marie Curie Fellowship. We wish him all the best in his future career. Good Luck!
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February 2020: Our new postdoc Rahul Kaushik and Erasmus student Wojciech Krzemien (Poznan, Poland) have already joined our research group!
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July 2019: Our recent paper "Karlikova M, Cermakova V, Demuth J, Valer V, Miletin M, Novakova V, Zimcik P, Magnesium tetrapyrazinoporphyrazines: tuning of the pKa of red-fluorescent pH indicators, Dalton Transactions, 2019, 48, 6162-6173" was highlighted as a Hot paper and is free to access until 23rd August 2019
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July 2019: Great success of Azaphthalocyanine group on the XIII International Conference "Sytnhesis and Application od Porphyrns and Their Analogues" in Kostroma! Ivan Skvortsov was awarded for the Best Student Presentation for his project dealing with aza-analogues of subphthalocyanines, which he made during his research stay in our lab from January to June 2019. Furhter, Jan Kollár won a prize for the Best student poster with his project on water-soluble phthalocyanines for photodynamic therapy.
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for the news archives click here
Selected publications
- Cidlina A, Miletin M, Fathi-Rasekh M, Nemykin V, Zimcik P, Novakova V, OFF-ON-OFF Red-Emitting Fluorescent Indicators for a Narrow pH Window, Chemistry - A European Journal, 2017, 23, 8, 1795-1804. Highlighted in Chemistry Views and selected for Front Cover and Cover Profile
- Donzello MP, Ercolani C, Novakova V, Zimcik P, Stuzhin PA, Tetrapyrazinoporphyrazines and Their Metal Derivatives. Part I: Synthesis and Basic Structural Information, Coordination Chemistry Reviews, 2016; 309: 107-179.
- Machacek M, Demuth J, Cermak P, Vavreckova M, Hruba L, Jedlickova A, Kubat P, Simunek T, Novakova V, Zimcik P, Tetra(3,4-pyrido)porphyrazines caught in the cationic cage: toward nanomolar active photosensitizers, Journal of Medicinal Chemistry, 2016, DOI: 10.1021/acs.jmedchem.6b01140. Open Access, ACS Author Choice
- Novakova V, Lásková M, Vavřičková H, Zimcik P, Phenol Substituted Tetrapyrazinoporphyrazines: pH dependent fluorescence in basic media, Chemistry - A European Journal, 2015, 21 (41): 14382–14392.
- Makhseed S, Machacek M, Alfadly W, Tuhl A, Vinodh M, Simunek T, Novakova V, Kubat P, Rudolf E, Zimcik P, Water soluble non-aggregating phthalocyanine and in vitro studies for photodynamic therapy, Chemical Communications, 2013; 49 (95): 11149-11151.
- Novakova V, Lochman L, Zajícová I, Kopecky K, Miletin M, Lang K, Kirakci K, Zimcik P, Azaphthalocyanines: Red Fluorescent probes for Cations, Chemistry - A European Journal, 2013; 19 (16): 5025-5028.
- Novakova V, Roh J, Gela P, Kuneš J, Zimcik P. Azaphthalocyanines with fused triazolo rings: formation of sterically stressed constitutional isomers. Chemical Communications. 2012; 48 (36): 4326-4328.