Research Funding

Azaphthalocyanine group

Ongoing

2025-2027 Grant Agency of Charles University: Low-symmetrical Si(IV) Phthalocyanines for Photodynamic Therapy of Cancer (432925)
2025-2027 Grant Agency of Charles University: Fluorescent J-dimers of Phthalocyanines (414725)

team members of the project Czech Science Foundation: Photoactive, supramolecular, and biocompatible materials suitable for antimicrobial photodynamic therapy (26-22222K) and the project New Technologies for Translational Research in Pharmaceutical Sciences (NETPHARM, CZ.02.01.01/00/22_008/0004607) co funded by the European Union.

Past

2024-2025 ERC-CZ: SPs-HEAT - Smart Photosenzitizers: Highly-Effective, Activatable and Aptamer-Targeted (LL2318)
2023-2025 Czech Science Foundation: J-Dimers of Phthalocyanines (23-06177S)
2023-2025 Grant Agency of Charles University: Employment of supramolecular interactions for influencing the photophysical properties of (aza)phthalocyanines (170223)
2023-2025 Grant Agency of Charles University: Synthesis and study of phthalocyanine analogues forming J-dimers (230723)
2021-2023 Czech Science Foundation: Non-metal complexes of porphyrazinoids for design of novel perspective photosensitizers and
fluorescence sensors (21-14919J)
2020-2023 Charles University - PRIMUS: Study of phthalocyanines for photodynamic therapy of cancer and bioimaging (PRIMUS/20/SCI/013)
2023 Grant Agency of Charles University: Novel selective approaches to low symmetry phthalocyanines (232523)
2020-2022 Czech Science Foundation: Supramolecular approach for improvement of photodynamic activity of photosensitizers (20-09212S)
2018-2021 Technology Agency of the Czech Republic: IVD PROBES (TH03010251)
2018-2020 Grant Agency of Charles University: Synthesis of modifiers increasing melting temperature of oligonucleotide probes (GAUK: 994218)
2017-2019 Czech Science Foundation: Azaphthalocyanines – dark quenchers in DNA hybridization probes (GAČR: 17-19094S)
2017-2019 Grant Agency of Charles University: Azaphthalocyanines as a universal quenchers of fluorescence in oligodeoxynucleotide probes (GAUK: 1168217)
2016-2018 Grant Agency of Charles University: Synthesis of anionic phthalocyanines as potential photodynamic active photosensitizers (GAUK: 1060216)
2012-2017 Charles University: UNCE project “Centre for investigation of toxic and protective effects of drugs on cardiovascular system” (UNCE 33/2012).
2014-2016 Czech Science Foundation (postdoc): Red-emitting Fluorescence Sensors Based on Azaphthalocyanine Structure: Study of Aza-Crown Recognition Moiety (GAČR: 14-02165P)
2013-2016 Czech Science Foundation: Development of new photosensitizers for photodynamic therapy and investigation of their mechanism of action on cellular level (GAČR: 13-27761S)
2014-2016 Grant Agency of Charles University: Study of recognition moieties of sensoric azaphthalocyanines (GAUK: 494214)
2014-2016 Grant Agency of Charles University: Study of the novel phthalocyanine and azaphthalocyanine photosensitizers for photodynamic therapy of tumors on cellular and molecular level (GAUK: 1916214)
2013-2015 Grant Agency of Charles University: Influence of structural factors on intramolecular charge transfer in azaphthalocyanines (GAUK 1182313).
2012-2015 Postdoci II UK CZ.1.07/2.3.00/30.0061
2011-2013 Czech Science Foundation: Red emitting photoinduced charge transfer sensors from the group of azaphthalocyanines(GAČR: P207/11/1200).
2012-2013 Pre-seed activity of UK: "IA05 Molekuly k přímé modifikaci DNA sond pro zvýšení citlivosti molekulárně biologických detekčních a diagnostických metod" (CZ.1.05/3.1.00/13.0284)
2010-2012 Grant Agency of Charles University: Phthalocyanine and azaphthalocyanine conjugates for photodynamic therapy prepared via click chemistry (GAUK 57810/2010).
2010-2012 Grant Agency of Charles University: Synthesis of phthalocyanine dyes and study of their use in quenching of fluorescence (GAUK 68110/2010)
2009-2012 Ministry of Industry and Trade: Inovation of real-time PCR probes (FR-TI1/112)
2011 Fond rozvoje vysokých škol: Inovace praktických cvičení předmětu Farmaceutická chemie - molekulové modely (295/2011 F6a)
2005-2011 Ministry of Education, Youth and Sports: Institutional research plan „Research of new drug structures” (MSM0021620822).
2008-2010 Grant Agency of the Academy of Sciences of the Czech Republic: Synthesis and evaluation of azaphthalocyanine derivatives as fluorescence quenchers (GAAV: KJB401100801)
2007-2009 Czech Science Foundation: Azaphthalocyanines - a new group of photosensitizers for PDT (GAČR: 203/07/P445).
2008 Fond rozvoje vysokých škol: Inovace syntetických úloh v praktických cvičeních předmětů Farmaceutická chemie a Technologie syntetických léčiv (688/2008 F6a).
2007-2009 Grant Agency of Charles University: Synthesis of asymmetric derivatives of tetrapyrazinoporphyrazines and their usage as "dark quenchers" (GAUK: 41107/B/2007)
2005-2007 Grant Agency of Charles University: Synthesis of unsymmetrical cationic azaphthalocyanines as photosensitizers in PDT (GAUK: 3317/2005).
2006 Fond rozvoje vysokých škol: Inovace praktické výuky předmětů Farmaceutická chemie a Přírodní a chemická léčiva (1540/2006 F6a).
2006 Fond rozvoje vysokých škol: Základní principy fotodynamické terapie v pregraduální výuce (1762/2006 G3).