Equipment and methods

Group of pathology and pharmacology of cardiovascular system

 

In vivo

Current mice models:mice.jpg

  • Transgenic overexpressing human Endoglin mice
  • Transgenic Leiden apolipoprotein E3 deficient mice

 

In vitro

Types of cells:cells.jpg

  • Human umbilical vein endothelial cells
  • Human aortic endothelial cells
  • Human coronary artery endothelial cells (healthy and from diabetes mellitus type II patients)
  • Hepatic stellate cells 
  • Liver sinusoidal endothelial cells
  • THP-monocytes

Methods

 

  • Histology and microscopy

  • Light and fluorescence immunohistochemistry

  • Western blot analysis and ELISA analysis

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  • Wire Myograph - functional analysis of blood vessels

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  • Flow cytometry and in vitro study

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