Workgroup of biological and medical sciences
Research group of pathology and pharmacology of cardiovascular system is focusing on the atherogenesis and endothelial dysfunction study in experimental animal models. The main methodological approaches are histology, immunohistochemistry (light and fluorescence microscopy), Western blot analysis, RT-PCR and functional analysis of blood vessels by means of DMT myograph.
The main object of research of the group of microbiology and immunology is testing of antimicrobial activity in vitro and implementation of new, valid and reproducible methods for the study of antimicrobial compound-microbe interaction. Another object of research is focused on extracellular vesicles secretion of the yeast Candida albicans and relationship of these vesicles to mechanisms of pathogenesis. For studies, these methodological approaches are used: light microscopy (fluorescent, confocal laser scanning microscopy), cultivation (aerobic, anaerobic, microaerophilic), spectrophotometric evaluation of microbial count and metabolic activity, isolation, concentration and purification of microbial proteins.
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