Research Funding

Ongoing

Czech Science Foundation

  • 20-14581Y "Transcriptomic, proteomic and functional analysis of carbonyl reductases in parasitic nematode Haemonchus contortus"
  • 18-08452S “Anthelmintics in plants – interactions with polyphenols biosynthesis and antioxidant defence”
  • 18-07724S "Circulation of anthelmintics in environment- does it contribute to drug resistance development in helminths?"
  • 18-09946S "Metabolism of terpenes and mechanisms of their toxic effects in human liver"
  • 18-07281Y "In vitro and ex vivo models to study drug-drug interactions of antiviral drugs on intestinal transporters"

Charles University Research Funding

  • START/MED/065 "Novel therapeutic approaches to the treatment of hepatic diseases" (2021-2023)
  • START/SCI/052 "Anthelmintics in the environment – detection, consequences, a possible solution" (2021-2023)
  • GAUK No. 1302120 "The investigation of biotransformation of reactive sesquiterpenes and their effect on the proteome of human hepatic cells" (2020-2023)
  • GAUK No. 1136120 "Monitoring of anthelmintic drugs in the environment" (2020-2023)
  • GAUK No. 1171620 „Efflux transporters of Haemonchus contortus and their role in resistance development“ (2020-2022)
  • GAUK No. 1568519 "Metabolic pathways of new potential anthelmintics in Haemonchus contortus and its host" (2019-2022)
  • UNCE18/SCI/012 "Centre of research of hosts-parasites interactions" 

European Union, European Structural and Investment Funds

  • Efficiency and Safety Improvement of Current Drugs and Nutraceuticals: Advanced Methods – New Challenges (EFSA–CDN);
    Project No: CZ.02.1.01/0.0/0.0/16_019/0000841; within the Operation Program Research, Development and Education (OP RDE), PA 1, IP 1, SO 1; OP RDE call: No. 02_16_019 Excellent Research

 

Past

Czech Science Foundation

  • 17-11954Y “UDP-glycosyltransferases in Haemonchus contortus –players in drug-resistance?”
  • No. 524/00/0514 “Biotransformation enzymes and metabolism of xenobiotics in ruminants”
  • No. 524/03/1361 “Benzimidazole anthelmintics and induction of biotransformation enzymes in farm animals“ 
  • No. 524/06/1345 “Biotransformation enzymes of ruminants and their parasites - significance for therapy of parasitoses and anthelmintic resistance”
  • No. 524/07/0611 “Dicrocoeliosis in farm animals - defence mechanisms of lancet fluke against anthelmintics”
  • No. 524/09/P121 “Modification of enzymes metabolizing xenobiotics during ageing”
  • No. P502/10/0217 “Drug-resistance development in helminths – possible mechanisms and defence”
  • No. P503/15-05325S “Anthelmintics in plants – uptake, biotransformation and transcriptional response“
  • No. P303/12/G163 “Centre of drug - dietary supplement interactions and nutrigenetics”

Charles University Research Funding

  • PRIMUS/17/SCI/4 “Úloha mikroRNA v lékové rezistenci hlístic”

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