Selected publications in past five years:


  1. Vokřál, I., Jirásko, R., Jedličková, V., Bártíková, H., Skálová, L., Lamka, J., Holčapek, M., Szotáková, B. The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel. Vet. Parasitol. 185 (2012) 168-174. (doi:10.1016/j.vetpar.2011.09.026)

    [Impact factor 2011: 2.579 ]

  2. V. Hanušová, I. Boušová, A. Pakostová, L. Skálová. The influence of oracin on reduction and toxicity of doxorubicin in hepatocytes and mammary epithelial cells MCF-10A. Xenobiotica 42 (2012) 571-579

    [Impact factor 2012: 1.791]

  3. Bártíková, H., Vokřál, I., Skálová, L., Kubíček, V., Firbasová, J., Briestenský, D., Lamka, J., Szotáková, B. Activity of drug metabolizing enzymes and biotransformation of selected anthelmintics in model tapeworm Hymenolepis diminuta. Parasitology 139 (2012) 809-818

    [Impact factor 2011: 2.961]

  4. Bártíková, H., Vokřál, I., Kubíček, V., Szotáková, B., Prchal, L., Lamka, J., Várady, M., Skálová, L. Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics. Vet. Parasitol. 187 (2012) 473-479 (doi:10.1016/j.vetpar.2012.02.008).

    [Impact factor 2012: 2.579]

  5. Vokřál, I., Bártíková, H., Prchal, L., Stuchlíková, L., Skálová, L., Szotáková, B., Lamka, J., Várady, M., Kubíček, V. The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics. Parasitology 139 (2012) 1309-1316

    [Impact factor 2011: 2.961]

  6. Boušová, I., Hájek, J., Dršata, J., Skálová, L. Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase. Xenobiotica 42 (2012) 872-879

    [Impact factor 2012: 1.791]

  7. Iva Boušová and Lenka Skálová. Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences. Drug Metabolism Reviews 44(4) (2012) 267–286

    [Impact factor 2012: 6.400]

  8. Vokřál, I., Jedličková, V., Jirásko, R., Stuchlíková, L., Bártíková, H., Skálová, L., Lamka, J., Holčapek, M., Szotáková, B. The metabolic fate of ivermectin in host (Ovis aries) and parasite (Haemonchus contortus). Parasitology 140 (2013) 361–367. (doi:10.1017/S0031182012001680)

    [Impact factor 2011: 2.961]

  9. Stuchlíková L, Jirásko R, Vokřál I, Lamka J, Spulák M, Holčapek M, Szotáková B, Bártíková H, Pour M, Skálová L. Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS. Anal Bioanal Chem. 405 (2013) 1705–1712

    [Impact factor 2012: 3.778]

  10. Szotáková, B., Bártíková, H., Hlaváčová, J., Boušová, I., Skálová, L. Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyl transferase and carbonyl reductase activities in rat and human. Xenobiotica 43 (2013) 679-685 (doi:10.3109/00498254.2012.756557)

    [Impact factor 2012: 1.791]

  11. Boušová I., Srbová L., Dršata J. (2012) Non-enzymatic glycation of aminotransferases and the possibilities of its modulation. In: Sharma RR (ed.), Enzyme Inhibition and Bioapplications, InTech, Rijeka, Croatia, pp. 85-114, ISBN 979-953-307-301-8

  12. Vokřál, I., Jirásko, R., Stuchlíková, L., Bártíková, H., Szotáková, B., Lamka, J., Várady, M., Skálová, L. Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics. Vet. Parasitol. 196 (2013) 373–381
    (doi: 10.1016/j.vetpar.2013.03.018)

    [Impact factor 2012: 2.381]

  13. Podlipná, R., Skálová, L., Seidlová, H., Szotáková, B., Kubíček, V., Jirásko, R., Vaněk, T., Vokřál, I. Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment. Bioresource Technology 144 (2013) 216-224
    (doi: 10.1016/j.biortech.2013.06.105)

    [Impact factor 2012: 4.750]

  14. Vyskočilová, E., Szotáková, B., Skálová, L., Bártíková, H., Hlaváčová, J., Boušová, I. Age-related changes in hepatic activity and expression of detoxification enzymes in male rats. BioMed Research International (2013), art. no. 408573

    [Impact factor 2012: 2.880]

  15. Lecová, L., Stuchliková, L., Lamka, J., Špulák, M., Várady, M., Skálová, L. Efficacy of monepantel against lower developmental stages of a multi-resistant and susceptible Haemonchus contortus isolates: an in vitro study. Helmintologia 50 (2013) 91-95
    (doi: 10.2478/s11687-013-0114-6)

    [Impact factor 2012: 0.783]

  16. Králová, V., Hanušová, V., Staňková, P., Knoppová, K., Čáňová, K., Skálová, L. Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines. Anti-Cancer Drugs 24 (2013) 911-919
    (doi: 10.1097/CAD.0b013e3283648c69)

    [Impact factor 2012: 2.230]

  17. Volková, M., Forstová-Křížová, V., Skálová, L., Trejtnar, F. Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 intestinal HCT-8 cells. Phytother. Res. 27 (2013) 1889-1893
    (doi: 10.1002/ptr.4992)

    [Impact factor 2012: 2.068]

  18. Bártíková, H., Skálová, L., Dršata, J., Boušová, I.: Interaction of anthocyanins with drug-metabolizing enzymes and antioxidant enzymes. Curr. Med. Chem. 20 (2013) 4665-4679
    (doi: 10.2174/09298673113209990153)

    [Impact factor 2012: 4.405]

  19. Landa, P., Skálová, L., Boušová, I., Kutil, Z., Langhasová, L., Lou, J.D., Vaněk, T. In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb. Pak. J. Pharm. Sci. 27 (2014) 103-106 
    (PMID: 24374437)

    [Impact factor 2012: 0.947]

  20. Hanušová, V., Tomšík, P., Kriesfalusyová, L., Pakostová, A., Boušová, I., Skálová, L. In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice. Pharmacol. Rep. 65 (2013) 445-452
    (PMID: 23744429)

    [Impact factor 2012: 1.965]

  21. Matoušková, P., Bártíková, H., Boušová, I., Hanušová, V., Szotáková, B., Skálová, L. Reference genes for Real-Time PCR quantification of messenger RNAs and microRNAs in mouse model of obesity. PLoS ONE 9(1) (2014): e86033. (doi:10.1371/journal.pone.0086033)

    [Impact factor 2013: 3.530]

  22. Bártíková, H., Boušová, I., Jedličková, P., Lněničková, K., Skálová, L., Szotáková, B. Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine. Molecules 19 (2014) 14948-14960 (doi:10.3390/molecules190914948)

    [Impact factor 2013: 2.095]

  23. Prchal L., Bártíková H., Bečanová A., Jirásko R., Vokřál I., Stuchlíková L., Skálová L., Kubíček V., Lamka J., Trejtnar F., Szotáková B. Biotransformation of anthelmintics and the activity of drug metabolizing enzymes in the tapeworm Moniezia expansa. Parasitology142 (5) (2015) 648-659 (doi:10.1017/S0031182014001711)

    [Impact factor 2013: 2.350]

  24. Lecova, L., Stuchlikova, L., Prchal, L., Skalova, L. Monepantel: the most studied new anthelmintic drug of recent years. Parasitology 141 (13) (2014) 1686-1698 (doi:10.1017/S0031182014001401)

    [Impact factor 2013: 2.350]

  25. Stuchlikova, L., Jirasko, R., Vokral, I., Valat, M., Lamka, J., Szotakova, B., Holcapek, M., Skalova, L. Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus). Drug testing and analysis 6 (10) (2014) 1055 -1062 (doi:10.1002/dta.1630)

    [Impact factor 2013: 2.816]

  26. Langhansova, L., Hanusova, V., Rezek, J., Stohanslova, B., Ambroz, M., Kralova, V., Vanek, T., Lou, J.D., Yun, Z.L., Yang, J., Skalova, L. Essential oil from Myrica rubra leaves inhibits cancer cell proliferation and induces apoptosis in several human intestinal lines. INDUSTRIAL CROPS AND PRODUCTS 59 (2014) 20-26 (doi:10.1016/j.indcrop.2014.04.018)

    [Impact factor 2013: 3.208]

  27. Matoušková, P., Bártíková H., Boušová, I., Szotáková, B., Martin, J., Skorkovská, J., Hanušová, V., Tománková, V., Anzenbacherova, E., Liskova, B., Anzenbacher, P., Skálová L. Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo. Journal of Functional Foods 10 (2014) 327-335 (doi:10.1016/j.jff.2014.06.026)

    [Impact factor 2013: 4.480]

  28. Ambrož, M., Boušová, I., Skarka, A., Hanušová, V., Králová, V., Matoušková, P. Szotáková, B. Skálová, L. The influence of sesquiterpenes from Myrica rubra on the antiproliferative and pro-oxidative effects of doxorubicin and its accumulation in cancer cells. Molecules 20 (8) (2015) 15343-15358. (doi:10.3390/molecules200815343)

    [Impact factor 2014: 2.146]

  29. Stuchlíková, L., Matoušková, P., Bártíková, H., Vokřál, I., Lamka, J., Štolcová, T., Pětníková, H., Szotáková, B., Kubíček, V., Skálová, L. Monepantel induces hepatic cytochromes P450 in sheep in vitro and in vivo. Chem.-Biol. Interact. 227 (2015) 63-68. (doi:10.1016/j.cbi.2014.12.025)

    [Impact factor 2014: 2.577]

  30. Bousova, I., Bartikova, H., Matouskova, P., Lnenickova, K., Zappe, L., Valentova, K., Szotakova, B., Martin, J., Skalova, L. Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice. Nutrition Res. (2015) 901-909. (doi:10.1016/j.nutres.2015.08.002)

    [Impact factor 2014: 2.472]

  31. Lecova, L., Ruzickova, M., Laing, R., Vogel, H., Szotakova, B., Prchal, L., Lamka, J., Vokral, I., Skalova, L., Matouskova, P. Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus. Mol. Biochem. Parasitol. 201 (2) (2015) 123-127. (doi:10.1016/j.molbiopara.2015.08.001)

    [Impact factor 2014: 1.787]

  32. Bartikova, H., Skalova, L., Valentova, K., Matouskova, P., Szotakova, B., Martin, J., Kvita, V., Bousova, I. Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo. Acta Pharm. 65 (1) (2015) 65-73. (doi:10.1515/acph-2015-0007)

    [Impact factor 2014: 0.912]

  33. Matouskova, P., Bartikova, H., Bousova, I., Levorova, L., Szotakova, B., Skalova, L. Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice. Drug Metab. Dispos. 43 (2) (2015) 258-265. (doi:10.1124/dmd.114.061176)

    [Impact factor 2014: 3.252]

  34. Bártíková, H., Skálová, L., Stuchlíková, L., Vokřál, I., Vaněk, T., Podlipná, R. Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment. Drug Metabolism Reviews 47 (2015) 374-387. (doi:10.3109/03602532.2015.1076437)

    [Impact factor 2014: 5.356]

  35. Bártíková, H., Podlipná, R., Skálová, L. Veterinary drugs in environment and their toxicity to plants. Chemosphere 144 (2016) 2290-2301. (doi:10.1016/j.chemosphere.2015.10.137)

    [Impact factor 2014: 3.340]

  36. Ambrož, M., Hanušová, V., Skarka, A., Boušová, I., Králová, V., Langhasová, L., Skálová, L. Essential oil from Myrica rubra leaves potentiated antiproliferative and pro-oxidative effect of doxorubicin and its accumulation in intestinal cancer cells. Planta Medica 82 (1-2) (2016) 89-96. (doi: 10.1055/s-0035-1558083)

    [Impact factor 2014: 2.152]

  37. Prchal, L., Vokřál, I., Kašný, M., Rejšková, L., Zajíčková, M., Lamka, J., Skálová, L., Lecová, L., Szotáková, B. Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna). Xenobiotica, 46(2) (2016) 132–140. (doi: 10.3109/00498254.2015.1060370)

    [Impact factor 2015: 1.723]

  38. Stuchlíková, L., Lecová, L., Jirásko, R., Lamka, J., Vokřál, I., Szotáková, B., Holčapek, M., V., Skálová, L. Comparison of biotransformation and efficacy of aminoacetonitrile anthelmintics in vitro. Drug Testing and Analysis 8 (2016) 214-220. (doi: 10.1002/dta.1806).

    [Impact factor 2015: 2.859]

  39. Prchal, L., Podlipná, R., Lamka, J., Dědková, T., Skálová, L., Vokřál, I., Lecová, L., Szotáková, B. Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination. Environmental Science and Pollution Research 3(13) (2016) 13015-22. (doi: 10.1007/s11356-016-6472-0).

    [Impact factor 2015: 2.760]

  40. Stuchlíková, L., Jirásko, R., Skálová, L., Pavlík, F., Szotáková, B., Holčapek, M., Podlipná, R. Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia). Chemosphere 157 (2016) 10-17. (doi:10.1016/j.chemosphere.2016.05.015)

    [Impact factor 2014: 3.698]

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